Uses
ChemicalBook > CAS DataBase List > N-Boc-N-methylethylenediamine

N-Boc-N-methylethylenediamine

Uses
Product Name
N-Boc-N-methylethylenediamine
CAS No.
121492-06-6
Chemical Name
N-Boc-N-methylethylenediamine
Synonyms
N-Boc-(2-Aminoethyl)-N-methylamine;tert-butyl 2-aminoethyl(methyl)carbamate;BOC,ME-EDA;CAS:121492-06-6;BUTTPARK 90\06-19;BOC-N-METHYLETHYLENEDIAMINE;N-(2-AMinoethyl)-N-Methylca;N-BOC-N-METHYLETHYLENEDIAMINE;1-BOC-1-METHYL-ETHYLENEDIAMINE;N-Boc-N-methyl-1,2-diaminoethane
CBNumber
CB3424935
Molecular Formula
C8H18N2O2
Formula Weight
174.24
MOL File
121492-06-6.mol
More
Less

N-Boc-N-methylethylenediamine Property

Melting point:
248-251 °C (decomp)
Boiling point:
79°C/0.4mmHg(lit.)
Density 
0.975 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.447
Flash point:
>100 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
9.44±0.10(Predicted)
form 
Liquid
color 
Clear colorless to pale yellow
BRN 
3588326
InChI
InChI=1S/C8H18N2O2/c1-8(2,3)12-7(11)10(4)6-5-9/h5-6,9H2,1-4H3
InChIKey
QYJVBVKFXDHFPQ-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)N(CCN)C
CAS DataBase Reference
121492-06-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
2734
WGK Germany 
3
HazardClass 
8
PackingGroup 
Ⅲ
HS Code 
2924190090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
15567
Product name
N-Boc-N-methylethylenediamine
Purity
≥97.0% (GC)
Packaging
1ml
Price
$130
Updated
2023/06/20
Sigma-Aldrich
Product number
15567
Product name
N-Boc-N-methylethylenediamine
Purity
≥97.0% (GC)
Packaging
5ml
Price
$181
Updated
2022/05/15
TCI Chemical
Product number
B4277
Product name
N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine
Purity
>95.0%(GC)(T)
Packaging
1mL
Price
$44
Updated
2025/07/31
TCI Chemical
Product number
B4277
Product name
N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine
Purity
>95.0%(GC)(T)
Packaging
5mL
Price
$132
Updated
2025/07/31
Usbiological
Product number
265320
Product name
Boc-N-methylethylenediamine
Packaging
1g
Price
$350
Updated
2021/12/16
More
Less

N-Boc-N-methylethylenediamine Chemical Properties,Usage,Production

Uses

N-Boc-N-methylethylenediamine is a compound useful in organic synthesis and other chemical processes.

Chemical Properties

Liquid

Uses

Mono-protected building block.

reaction suitability

reagent type: cross-linking reagent

Synthesis

24424-99-5

109-81-9

121492-06-6

Step 1: N-methylethylenediamine (11.8 mL, 134.9 mmol) was dissolved in acetonitrile (300 mL) and cooled to -30 °C. Subsequently, triethylamine (TEA, 7.46 mL, 53.9 mmol) was added to this solution, followed by dropwise addition of di-tert-butyl dicarbonate (Boc2O, 9.81 g, 45 mmol) in acetonitrile solution. The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the insoluble material was removed by Celite filtration. The filtrate was purified by silica gel column chromatography (elution gradient: 1:50→1:20→1:10 ethyl acetate/hexane) to afford tert-butyl N-(2-aminoethyl)-N-methylcarbamate (CXVIII) as a yellow oil (5.2 g, 29.9 mmol, 66% yield). The product was confirmed by electrospray ionization mass spectrometry (ESIMS) with molecular formula C8H18N2O2, m/z 175 (M + H).

References

[1] Patent: US2008/318957, 2008, A1. Location in patent: Page/Page column 72; 73
[2] Journal of Medicinal Chemistry, 2000, vol. 43, # 16, p. 3093 - 3102

N-Boc-N-methylethylenediamine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-Boc-N-methylethylenediamine Suppliers

Americas 1 Canada 2 China 176 Europe 1 Germany 5 India 7 Japan 1 Switzerland 3 United Kingdom 14 United States 40 Global 250
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
More
Less

View Lastest Price from N-Boc-N-methylethylenediamine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
N-Boc-N-methylethylenediamine 121492-06-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-13
Career Henan Chemical Co
Product
N-Boc-N-methylethylenediamine 121492-06-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-09

121492-06-6, N-Boc-N-methylethylenediamineRelated Search:

2-Butoxyethanol tert-Butyl peroxybenzoate Urethane Diethylene glycol monobutyl ether Diisobutyl phthalate N-METHYLETHYLENEDIAMINE tert-Butyl carbazate tert-Butyl acetate 4-Aminobenzoic acid N,N-Dimethylethylenediamine Methyl anthranilate 2-(2-Aminoethylamino)ethanol tert-Butyl 4-aminobenzoate N,N,N',N'-Tetramethylethylenediamine N-(1-Naphthyl)ethylenediamine dihydrochloride Butyl acrylate Thiophanate-methyl tert-Butanol

  • TERT-BUTYL N-(2-AMINOETHYL)-N-METHYLCARBAMATE
  • N-T-BUTYLOXYCARBONYL-N-METHYL-ETHYLENEDIAMINE
  • N-TERT-BUTYLOXYCARBONYL-N-METHYL-ETHYLENEDIAMINE
  • N-BOC-N-METHYLETHYLENEDIAMINE
  • N-(2-AMINOETHYL)-N-METHYL CARBAMIC ACID TERT-BUTYL ESTER
  • N-(2-AMINOETHYL)-N-BOC-METHYLAMINE
  • BOC,ME-EDA
  • BOC-N-METHYLETHYLENEDIAMINE
  • BUTTPARK 90\06-19
  • (2-AMINO-ETHYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER
  • 1-BOC-1-METHYL-ETHYLENEDIAMINE
  • N-(2-Aminoethyl)-N-methyl carbamic acid tert-butyl
  • N-Boc-(2-Aminoethyl)-N-methylamine
  • Carbamic acid, N-(2-aminoethyl)-N-methyl-, 1,1-dimethylethyl ester
  • N-Boc-N-methylethylenediamine ,98%
  • tert-butyl 2-aminoethyl(methyl)carbamate
  • tert-butyl (2-aminoethyl)methylcarbamate(SALTDATA: FREE)
  • 2-(N-Boc-N-methylamino)ethylamine
  • 1-BOC-1-methyl-ethylenediamine-HCl
  • 2-Methylpropan-2-yl N-(2-AMinoethyl)-N-MethylcarbaMate
  • N-(2-AMinoethyl)-N-Methylca
  • N-(2-AMinoethyl)-N-Methyl-carbaMic Acid 1,1-DiMethylethyl Ester
  • N-(2-AMinoethyl)-N-Methyl-N-(tert-butoxycarbonyl)aMine
  • N-(tert-Butoxycarbonyl)-N-methylethane-1,2-diamine, tert-Butyl (2-aminoethyl)methylcarbamate
  • N-Methylethane-1,2-diamine, N-BOC protected
  • N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine
  • N1-BOC-N1-METHYL-1,2-ETHYLENEDIAMINE
  • Boc-N-methylethylenediamine≥ 98% (GC)
  • N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine &gt
  • N-(tert-Butoxycarbonyl)-N-methyl-1,2-diaminoethane
  • N-Boc-N-methyl-1,2-diaminoethane
  • N-Boc-N-methyl-1,2-ethylenediamine
  • N-Boc-N-methylethylenediamine USP/EP/BP
  • N-Boc-N-methylethylenediamine 121492-06-6
  • 2-Methyl-2-propanyl (2-aminoethyl)methylcarbamate
  • CAS:121492-06-6
  • <i>N</i>-Boc-<i>N</i>-methylethylenediamine
  • 121492-06-6
  • Building Blocks
  • Nitrogen Compounds
  • Organic Building Blocks
  • Protected Amines
  • Bifunctional Linkers
  • Building Blocks
  • Chemical Biology
  • Chemical Synthesis
  • Linkers and Crosslinkers
  • Nitrogen Compounds
  • Organic Building Blocks
  • Protected Amines
  • Small molecule