Lupeol
Description References- Product Name
- Lupeol
- CAS No.
- 545-47-1
- Chemical Name
- Lupeol
- Synonyms
- Lupe;LUPEOL;Lupenol;Lupinol;Clerodol;B-VISCOL;MONOGYNOL;NSC 90487;LUPEOL(P);Lupeol-RM
- CBNumber
- CB3429132
- Molecular Formula
- C30H50O
- Formula Weight
- 426.73
- MOL File
- 545-47-1.mol
Lupeol Property
- Melting point:
- 215°
- alpha
- D20 +27.2° (c = 4.8 in chloroform)
- Boiling point:
- 482.1°C (rough estimate)
- Density
- 0.9457
- refractive index
- 1.4910 (estimate)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 15.19±0.70(Predicted)
- color
- White to Off-White
- optical activity
- +26.420 (c 3.51, CHCl3)
- InChIKey
- MQYXUWHLBZFQQO-QGTGJCAVSA-N
- LogP
- 10.460 (est)
- CAS DataBase Reference
- 545-47-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Lupeol(545-47-1)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 2
- RTECS
- OK5763000
- HS Code
- 29061990
- Hazardous Substances Data
- 545-47-1(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- L5632
- Product name
- Lupeol
- Purity
- ≥94%
- Packaging
- 25mg
- Price
- $131
- Updated
- 2024/03/01
- Product number
- 18692
- Product name
- Lupeol
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $183
- Updated
- 2024/03/01
- Product number
- 11215
- Product name
- Lupeol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 11215
- Product name
- Lupeol
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $50
- Updated
- 2024/03/01
- Product number
- L5632
- Product name
- Lupeol
- Purity
- ≥94%
- Packaging
- 100mg
- Price
- $391
- Updated
- 2024/03/01
Lupeol Chemical Properties,Usage,Production
Description
Lupeol is a kind of novel anti-inflammatory and anti-cancer dietary triterpene that can be found in white cabbage, green pepper, strawberry, olive, mangoes and grapes. In recent years, much progress has been made on the application of this molecule for clinical treatment of various kind of disorders. On the one hand, it has been extensively studied that it is capable of inhibiting inflammation under both in vitro and in animal models. Studies have shown that Lupeol is a multi-target agent during its anti-inflammation effect, targeting on many key molecular pathways involving nuclear factor kappa B (NFκB), cFLIP, Fas, Kras, phosphatidylinositol-3-kinase (PI3K)/Akt and Wnt/β-catenin. On the other hand, Lupeol has strong anti-tumor effect during treatment of various cancer types such as prostate, skin, pancreatic and breast cancer. The anti-tumor effect might be related to its potential to modulate important signaling pathways such as nuclear factor kappa B (NFκB) and the phosphatidylinositol 3-kinase [PI3K] /Akt (protein kinase B pathway), which are crucial during tumorigenesis.
References
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764818/
https://en.wikipedia.org/wiki/Lupeol
Chemical Properties
White powder
Uses
antineoplastic
Uses
Lupeol was used as reference standard in method development and validation of lupeol from Vernonia Cinerea using HPLC method. It has been used as a standard for the identification and quantification of triterpenoids in blueberry cuticular wax by GC.
Uses
Abundant plant triterpene. Occurs in the skin of lupin seeds, in circle, in the latex of fig trees and of rubber plants. It was detected in cocoons of Bombyx mori.
Definition
ChEBI: A pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in m ny edible fruits and vegetables.
General Description
Lupeol is a novel anti-cancer and anti-inflammatory dietary triterpene. They help in stabilizing phospholipid bilayers in plant cell membranes. In general, this group contains 28-29 carbons along with carbon-carbon double bonds, usually one in the sterol nucleus and at times a second in the alkyl side chain.
target
Caspase | PARP | GSK-3 | Akt | PI3K | Wnt/β-catenin | c-Myc | IL Receptor | Bcl-2/Bax | NF-kB | ROS | TNF-α | STAT
Lupeol Preparation Products And Raw materials
Raw materials
Preparation Products
Lupeol Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
View Lastest Price from Lupeol manufacturers
- Product
- Lupeol 545-47-1
- Price
- US $79.00-38.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-11-18
- Product
- Lupeol 545-47-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500
- Release date
- 2023-08-02
- Product
- Lupeol 545-47-1
- Price
- US $93571.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2021-06-08