Methoxyamine Hydrochloride

Methoxyamine hydrochloride Application

Product Name: Methoxyamine Hydrochloride
CAS No.: 593-56-6
Chemical Name: Methoxyamine Hydrochloride
Synonyms: METHOXYAMINE HYDROCHLORIDE;O-METHYLHYDROXYLAMINE HYDROCHLORIDE;MAH;METHOXYLAMINE HYDROCHLORIDE;METHYLHYDROXYLAMINE HYDROCHLORIDE;O-METHOXYAMINE HCL;O-METHYLHYDROXYLAMINE HCL;METHOXYAMINE HCL;O-METHYLHYDROXYLAMMONIUM CHLORIDE;O-METHYLHYDROXYAMINE HYDROCHLORIDE
CBNumber: CB3439014
Molecular Formula: CH5NO.ClH
Formula Weight: 83.52
MOL File: 593-56-6.mol

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Methoxyamine Hydrochloride Property

Melting point:: 151-154 °C(lit.)
Boiling point:: 105-110°C
Density: 1.1 g/mL at 25 °C
refractive index: n20/D 1.4021
storage temp.: Sealed in dry,Room Temperature
solubility: alcohol: soluble(lit.)
form: Crystalline Powder
color: White to very faint yellow
Water Solubility: SOLUBLE
Sensitive: Hygroscopic
Merck: 14,5989
BRN: 3589723
InChIKey: XNXVOSBNFZWHBV-UHFFFAOYSA-N
CAS DataBase Reference: 593-56-6(CAS DataBase Reference)
EPA Substance Registry System: O-Methylhydroxylamine hydrochloride (593-56-6)

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Safety

Hazard Codes: C,Xi,N
Risk Statements: 34-36/37/38-50-43-20/21/22-37-35
Safety Statements: 3-24-26-36/37/39-45-61-24/25-27
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
RTECS: NC3980000
F: 3-10
Hazard Note: Corrosive/Hygroscopic
TSCA: Yes
HS Code: 2928 00 90
HazardClass: 8
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 225517
Product name: Methoxylamine hydrochloride solution
Purity: 25-30 wt. % in H2O
Packaging: 25g
Price: $71.4
Updated: 2023/06/20

Sigma-Aldrich

Product number: 225517
Product name: Methoxylamine hydrochloride solution
Purity: 25-30 wt. % in H2O
Packaging: 100g
Price: $150
Updated: 2023/06/20

Sigma-Aldrich

Product number: 89803
Product name: Methoxyamine hydrochloride
Purity: for GC derivatization, LiChropur?, 97.5-102.5% (AT)
Packaging: 1G
Price: $41.7
Updated: 2022/05/15

Sigma-Aldrich

Product number: 89803
Product name: Methoxyamine hydrochloride
Purity: for GC derivatization, LiChropur?, 97.5-102.5% (AT)
Packaging: 5G
Price: $140
Updated: 2022/05/15

TCI Chemical

Product number: M0343
Product name: O-Methylhydroxylamine Hydrochloride
Purity: >97.0%(N)(T)
Packaging: 25g
Price: $48
Updated: 2024/03/01

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Methoxyamine Hydrochloride Chemical Properties,Usage,Production

Methoxyamine hydrochloride

Methoxyamine hydrochloride (also known as O-methylhydroxylamine hydrochloride; Methoxyamine; Methoxyamine hydrochloride (OMHA), is an important medicine, pesticide intermediates. Its major applications are as follows:

it can be used for color photography and film printing.
it is used as a reducing agent in organic synthesis industry for preparation of oximes.
the field of medicine: it can be used for the synthesis of second-generation cephalosporins antibiotics cefuroxime (ester), neopropene, norethindine and hydroxyurea.
the field of pesticides: the synthesis of new efficient, low-toxicity bactericidal metominostrobin.
It is mainly produced by sodium nitrite method in our country.

The similar compound of methoxyamine hydrochloride, the ethoxylamine hydrochloride is mainly used for the production of herbicides, oxycarbazone, diltiazem and other herbicides.

Application

Used as a methoxyamine reagent, also used in the production of the side chain of Cefuroxime and other new drugs
Used for pesticide synthesis.
Use for pharmaceuticals production
Used for the preparation of O-methyloxime together with aldehydes or ketones.

Description

Methoxamine hydrochloride, also known as methoxamine hydrochloride, O-methyl hydroxylamine hydrochloride. It is a white crystalline powder, and its fusing point is 149 ~ 152 DEG C, soluble in water, dissolved in alcohol, insoluble in ether and toluene, etc., and the solution is in acid. Methoxamine hydrochloride is an important chemical and medicine intermediate, can be used for the development and printing of color photography and film, and is widely used in the synthesis of medicine, functional dye, low-toxin farm chemicals, and new herbicides. Methoxamine hydrochloride is mainly used in the synthesis of s-generation cephalosporin product cephalofruxin in medical, and sulfamethoxazole; alkynes promise are bright, the synthesis of hydroxyurea, etc.; Agricultural chemicals aspect is then mainly used in the kresoxim-methyl of synthesizing efficient low toxicity.

Chemical Properties

White to very faintly yellow crystalline powder

Uses

antineoplastic, hydroxymethyltransferase inhibitor

Uses

Methoxylamine is a methoxime derivative used as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry

Uses

Methoxylamine hydrochloride is used as a reagent in the preparation of O-methyl oximes from aldehydes. It is orally bioavailable small molecule inhibitor with potential adjuvant activity. It is also used as internal standard for prostaglandin assays by gas chromatography-mass spectrometry.

General Description

Off-white crystals.

Air & Water Reactions

Water soluble.

Reactivity Profile

In aqueous solution, Methoxyammonium chloride behaves as an acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Fire Hazard

Flash point data for Methoxyammonium chloride are not available. Methoxyammonium chloride is probably combustible.

Purification Methods

Crystallise the hydrochloride from absolute EtOH or EtOH by addition of diethyl ether. [Kovach et al. J Am Chem Soc 107 7360 1985, Beilstein 1 IV 1252.]

Methoxyamine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-NITRO-PYRIDIN-3-YLAMINE PYRIDINE-2,3,6-TRIAMINE

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Methoxyamine Hydrochloride Suppliers

Americas 1 Belgium 5 Canada 4 China 539 Europe 3 France 1 Germany 10 India 28 Japan 10 Slovakia 1 Switzerland 3 The Netherlands 1 Ukraine 1 United Kingdom 16 United States 64 Global 687

TCI Chemicals (India) Pvt. Ltd.

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View Lastest Price from Methoxyamine Hydrochloride manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Methoxyammonium chloride 593-56-6
Price: US $35.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-05-29

Apeloa production Co.,Limited

Product: O-Methoxyamine HCl 593-56-6
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000
Release date: 2024-06-20

hebei hongtan Biotechnology Co., Ltd

Product: Methoxyammonium chloride 593-56-6
Price: US $30.00/kg
Min. Order: 1000kg
Purity: 98%
Supply Ability: 2000kg
Release date: 2024-05-17

593-56-6, Methoxyamine HydrochlorideRelated Search:

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Methoxyamine Hydrochloride (OMHA)

Methoxylamine solution hydrochloride

O-Methylhydroxylamine hydrochloride, Methoxylamine hydrochloride, O-Methoxyamine HCl

O-Methylhydroxylamine hydrochloride, Methoxylamine hydrochloride

O-Methylhydroxylamine hydrochloride ,99%

O-Methylhydroxylamine·hydrochloric acid

O-Methoxylamine Hydrochloride

O-Methylhydroxylamine hydrochloride, 30% aqueous solution

Methoxyamine Hydrochloride Methoxylamine Hydrochloride

amine hydrochL

Methoxyammoniumchlorid

methoxyammonium chloride

METHOXYAMINE HCL

METHOXYAMINE HYDROCHLORIDE

METHOXYLAMINE HYDROCHLORIDE

METHYOXYAMINE HCL

METHYLHYDROXYLAMINE HYDROCHLORIDE

Hydroxylamine,O-methyl-,hydrochloride

methyloxyammoniumchloride

o-methyl-hydroxylaminhydrochloride

Methoxylamine hydrochloride or O-methylhydrolamine

O-METHOXYAMINE HCL

METHOXYLAMINE HYDROCHLORIDE, 25-30 WT. % SOLUTION IN WATER

O-MethoxylamineHydrochloride99%

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Methoxylaminehydrochloride,25-30%aq.soln.

Methoxyamine hydrochloride, (Aminooxy)methane hydrochloride

O-METHYLHYDROXYLAMMONIUM CHLORIDE FOR SY

MethoxyaMine hydrochloride 98%

O-Methylhydroxylamine hydrochloride, 99%, for synthesis

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Relugolix Impurity 86

Methoxyamine hydrochloride H3C-O HCI

593-56-6