5-BROMO-3-HYDROXY (1H)INDAZOLE

Product Name: 5-BROMO-3-HYDROXY (1H)INDAZOLE
CAS No.: 7364-27-4
Chemical Name: 5-BROMO-3-HYDROXY (1H)INDAZOLE
Synonyms: 5-Bromo-1H-indazol-3-ol;5-Bromoindazol-3(2H)-one;5-BROMO-3-HYDROXYINDAZOLE;5-BROMO-3-HYDROXY (1H)INDAZOLE;5-BROMO-1,2-DIHYDRO-INDAZOL-3-ONE;5-broMo-1,2-dihydro-3H-Indazol-3-one;3H-Indazol-3-one, 5-broMo-1,2-dihydro-
CBNumber: CB3439478
Molecular Formula: C7H5BrN2O
Formula Weight: 213.03
MOL File: 7364-27-4.mol

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5-BROMO-3-HYDROXY (1H)INDAZOLE Property

Boiling point:: 268.4±19.0 °C(Predicted)
Density: 1.728±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: solid
pka: 11.02±0.20(Predicted)
Appearance: Light brown to brown Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: B696348
Product name: 5-Bromo-1h-indazol-3-ol
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144410
Product name: 5-Bromo-1H-indazol-3-ol
Packaging: 250mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144410
Product name: 5-Bromo-1H-indazol-3-ol
Packaging: 500mg
Price: $105
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144410
Product name: 5-Bromo-1H-indazol-3-ol
Packaging: 1g
Price: $180
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0366726
Product name: 5-BROMO-1H-INDAZOL-3-OL
Purity: 95.00%
Packaging: 250MG
Price: $196.35
Updated: 2021/12/16

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5-BROMO-3-HYDROXY (1H)INDAZOLE Chemical Properties,Usage,Production

Chemical Properties

White to yellow to gray to brown Solid

Uses

5-BROMO-3-HYDROXY (1H)INDAZOLE is a potential pharmaceutical intermediate, commonly used in the preparation of various drugs and biologically active compounds.

Synthesis

57381-59-6

7364-27-4

Part B: Methyl 5-bromo-2-fluorobenzoate (1.02 g, 4.2 mmol) was dissolved in 8 mL of ethanol and hydrazine monohydrate (4.0 mL, 80 mmol) was added. The reaction mixture was placed in a Biotage microwave reactor and stirred at 100 °C for 30 min. The reaction was found to be incomplete by LCMS, so the mixture was concentrated and fresh ethanol (6 mL) and hydrazine monohydrate (6 mL) were added. The reaction mixture was again placed in a microwave reactor and stirred at 100 °C for 30 min. Upon completion of the reaction, the mixture was concentrated to dryness to afford the target product 5-bromo-1H-indazol-3-ol (801 mg, 89% yield). HPLC-MS analysis results: t R = 1.21 min (UV 254 nm); mass calculated value C7H5BrN2O 212.0/214.0, measured value LCMS m/z 213.1/215.1 (M + H ).

References

[1] Patent: WO2010/54279, 2010, A1. Location in patent: Page/Page column 109-110
[2] Patent: WO2017/46318, 2017, A1. Location in patent: Page/Page column 54; 55
[3] Patent: WO2015/150565, 2015, A1. Location in patent: Page/Page column 75; 76

5-BROMO-3-HYDROXY (1H)INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-3-HYDROXY (1H)INDAZOLE Suppliers

China 82 Germany 1 India 1 United Kingdom 3 United States 9 Global 96

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
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Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
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Advantage: 64

Spectrum Chemical Manufacturing Corp.

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Wuhan TCASChem Technology Co., Ltd.

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NovoChemy Ltd.

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SynAsst Chemical.

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Country: China
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Shanghai Devinchem Ltd

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Email: sales@devinchem.com
Country: China
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Shanghai Meishui Chemical Technology Co., Ltd

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Fax: 021-33250306
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Bide Pharmatech Ltd.

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Country: China
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Advantage: 60

Shanghai YuYuan Pharmaceutical Co., Ltd.

Tel: 13052276172
Fax: 13052276172
Email: product@yuyuanpharm.com
Country: China
ProdList: 493
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View Lastest Price from 5-BROMO-3-HYDROXY (1H)INDAZOLE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-3-HYDROXY (1H)INDAZOLE 7364-27-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-3-HYDROXY (1H)INDAZOLE 7364-27-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 5-BROMO-3-HYDROXY (1H)INDAZOLE 7364-27-4
Price: US $1.00/g
Min. Order: 1g
Purity: 95%~99%
Supply Ability: per week 100kg
Release date: 2019-09-10

7364-27-4, 5-BROMO-3-HYDROXY (1H)INDAZOLERelated Search:

5-BROMO-1H-INDAZOL-3-AMINE 1H-Indazole-7-carboxamide(9CI) 3-BROMO-4-FLUORO (1H)INDAZOLE 1-METHYL-5-NITRO-1H-INDAZOLE 6-Bromo-1H-indazol-3-ol 2H-INDAZOLE, 5-CHLORO-2-METHYL- 5-NITRO INDAZOLE CARBOXALDEHYDE 3-Bromo-5-chloro-1H-indazole 3-IODO-6-METHOXY-1H-INDAZOLE 5-CHLORO-3-IODO-1H-INDAZOLE 6-(TRIFLUOROMETHYL)-1H-INDAZOLE 3-METHYL-5-NITRO-1H-INDAZOLE 4-Fluoro-3-iodo-1H-indazole 5-Chloro-1-methyl-1H-indazole 3,5-DICHLORO (1H)INDAZOLE 4-METHOXY (1H)INDAZOLE METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE 5-Bromoindazole

3H-Indazol-3-one, 5-broMo-1,2-dihydro-

5-broMo-1,2-dihydro-3H-Indazol-3-one

5-BROMO-3-HYDROXY (1H)INDAZOLE

5-BROMO-1,2-DIHYDRO-INDAZOL-3-ONE

5-BROMO-3-HYDROXYINDAZOLE

5-Bromo-1H-indazol-3-ol

5-Bromoindazol-3(2H)-one

7364-27-4