LUPENONE

Product Name: LUPENONE
CAS No.: 1617-70-5
Chemical Name: LUPENONE
Synonyms: LUPENONE;-en-3-one;Lup-20(29);Aids082905;Aids-082905;LUPENONE(RG);18-LUPEN-3-ONE;Lup-20(29)-en-3-one;Lupa-20(30)-ene-3-one;5α-Lup-20(29)-en-3-one
CBNumber: CB3447619
Molecular Formula: C30H48O
Formula Weight: 424.7
MOL File: 1617-70-5.mol

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LUPENONE Property

Melting point:: 165-167°C
Boiling point:: 485.7±14.0 °C(Predicted)
Density: 1.115 g/cm3(Temp: 18 °C)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: White
LogP: 10.400 (est)

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Safety

Hazard Codes: Xi
HS Code: 29142990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R205265
Product name: LUP-20(29)-EN-3-ONE
Purity: AldrichCPR
Packaging: 1MG
Price: $113
Updated: 2025/07/31

Usbiological

Product number: 453973
Product name: Lupenone
Packaging: 2.5mg
Price: $496
Updated: 2021/12/16

TRC

Product number: L474840
Product name: Lupenone
Packaging: 10mg
Price: $595
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594672
Product name: Lupenone
Packaging: 10mg
Price: $513.4
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb105776
Product name: Lupenone
Purity: >98%,Standard References Grade
Packaging: 20mg
Price: $569.5
Updated: 2021/12/16

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LUPENONE Chemical Properties,Usage,Production

Chemical Properties

White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dandelion, bamboo leaves and Adenophora australis.

Uses

Lupenone is a lupane triterpenoid with antioxidant and anticholinesterase activity. It also a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor.

Definition

ChEBI: A natural product found in Cupania cinerea.

in vivo

Lupenone (6, 12, 24 mg/kg/day, gavage for 6 weeks) improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/ CTGF-related fibrosis^[2].

Animal Model:	Spontaneous type 2 diabetic nephropathy db/db mouse models^[1]
Dosage:	6, 12, 24 mg/kg
Administration:	i.g.
Result:	Maintained the fasting blood glucose. Reduced glycosylated hemoglobin, insulin, and 24 h proteinuria levels. Regulated changes in biochemical indicators

IC 50

Trypanosoma

LUPENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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LUPENONE Suppliers

China 112 Germany 2 India 2 United Kingdom 3 United States 14 USA 1 Global 134

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

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View Lastest Price from LUPENONE manufacturers

Career Henan Chemical Co

Product: LUPENONE 1617-70-5
Price: US $1.00/KG
Min. Order: 1 mg
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-25

1617-70-5, LUPENONERelated Search:

Madecassoside Madecassic acid dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate roburic acid Terrestrosin K Terrestrosin D Carboxyatractyloside Pachymic acid Betulonicacid LUPENONE Δ1-Lupenone Betulonicacidmethylester N-[3-OXO-LUP-20(29)-EN-28-OYL]AMINOACETIC ACID N-[3-OXO-LUP-20(29)-EN-28-OYL]-3-AMINOPROPIONIC ACID METHYL ESTER N-[3-OXO-LUP-20(29)-EN-28-OYL]AMINOACETIC ACID METHYL ESTER Lupenone I LUPENONE(REAGENT / STANDARD GRADE) N-[3-OXO-LUP-20(29)-EN-28-OYL]-3-AMINOPROPIONIC ACID

Aids-082905

LUPENONE

18-LUPEN-3-ONE

-en-3-one

Lup-20(29)

LUPENONE(RG)

5α-Lup-20(29)-en-3-one

Lup-20(29)-en-3-one

Lupa-20(29)-ene-3β-one

Lupa-20(30)-ene-3-one

(1R,3Ar,4S,5ar,5br,7ar,11ar,11br,13ar,13br)-1-isopropenyl-3A,5A,5B,8,8,11A-hexamethyl-eicosahydro-cyclopenta[A]chrysen-9-one

Aids082905

(1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysen-9-one

(1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-Hexamethyl-1-(prop-1-en-2-yl)icosahydro-9H-cyclopenta[a]chrysen-9-one

1617-70-5

1657-70-5

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