ChemicalBook > CAS DataBase List > Angiotensin II human acetate

Angiotensin II human acetate

Product Name
Angiotensin II human acetate
CAS No.
68521-88-0
Chemical Name
Angiotensin II human acetate
Synonyms
HYPERTENSIN II;Ang II acetate;DRVYIHPF acetate;ANGIOTENSIN , HUMAN;Angiotensin Ⅱ, human;Angiotensin II xacetate;ANGIOTENSIN II ACETATE SALT;ANGIOTENSIN II ACETATE HUMAN;angiotensin ii human acetate;ANGIOTENSIN II, HUMAN, SYNTHETIC
CBNumber
CB3454530
Molecular Formula
C52H75N13O14
Formula Weight
1106.25
MOL File
68521-88-0.mol
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Angiotensin II human acetate Property

storage temp. 
−20°C
solubility 
H2O: 25 mg/mL, clear, colorless
form 
powder
color 
orange
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Safety

WGK Germany 
3
3-10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17150
Product name
Angiotensin II (human) (acetate)
Purity
≥90%
Packaging
1 mg
Price
$25
Updated
2024/03/01
Cayman Chemical
Product number
17150
Product name
Angiotensin II (human) (acetate)
Purity
≥90%
Packaging
5 mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
17150
Product name
Angiotensin II (human) (acetate)
Purity
≥90%
Packaging
10 mg
Price
$94
Updated
2024/03/01
Cayman Chemical
Product number
17150
Product name
Angiotensin II (human) (acetate)
Purity
≥90%
Packaging
25 mg
Price
$176
Updated
2024/03/01
Chem-Impex
Product number
32970
Product name
Angiotensin II acetate salt
Purity
≥ 99% (HPLC)
Packaging
5MG
Price
$30
Updated
2021/12/16
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Angiotensin II human acetate Chemical Properties,Usage,Production

Uses

Angiotensin II human acetate (Angiotensin II acetate) is a vasoconstrictor that mainly acts on the AT1 receptor. It stimulates sympathetic nervous stimulation and increases aldosterone biosynthesis and renal actions. It also induces the growth of vascular smooth muscle cells. It increases collagen type I and III synthesis in fibroblasts, weakening the vascular wall, myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis.

in vitro

Most of the known actions of Angiotensin II (Ang II) human acetate are mediated by AT1 receptors; the AT2 receptor regulates blood pressure and renal function. Angiotensin II human acetate raises blood pressure (BP) through several actions, the most important ones being vasoconstriction, sympathetic nervous stimulation, increased aldosterone biosynthesis, and renal actions. Other Angiotensin II human acetate actions include induction of growth, cell migration, and mitosis of vascular smooth muscle cells, increased synthesis of collagen type I and III in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. These actions are mediated by type 1 Ang II receptors (AT1). Angiotensin II (1 nM) induces the expression of LOX-1 and VEGF and enhances capillary formation from human coronary endothelial cells in Matrigel assay. Angiotensin II -mediated expression of LOX-1 and VEGF, capillary formation, intracellular reactive oxygen species generation, and phosphorylation of p38 as well as p44/42 mitogen-activated protein kinases were suppressed by anti-LOX-1 antibody, nicotinamide-adenine dinucleotide phosphate oxidase inhibitor apocynin and the Ang II type 1 receptor blocker Losartan, but not by the Ang II type 2 receptor blocker PD123319.

Angiotensin II human acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Angiotensin II human acetate Suppliers

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View Lastest Price from Angiotensin II human acetate manufacturers

Dorne Chemical Technology co. LTD
Product
ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT 68521-88-0
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
Shanghai Affida new material science and technology center
Product
Angiotensin II 68521-88-0
Price
US $0.00-0.00/Box
Min. Order
1Box
Purity
99
Supply Ability
50000KG/month
Release date
2024-04-26
Shandong Hanjiang Chemical Co., Ltd
Product
angiotensin 2 68521-88-0
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10T
Release date
2024-01-11

68521-88-0, Angiotensin II human acetateRelated Search:


  • ANGIOTENSIN II ACETATE SALT
  • ANGIOTENSIN II HUMAN ACETATE SALT
  • ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT
  • HYPERTENSIN II
  • ANGIOTENSIN II ACETATE HUMAN
  • ANGIOTENSIN II-FLUORESCEIN SYNTHETIC >81 %
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  • ANGIOTENSIN , HUMAN
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  • Angiotensin II xacetate
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  • DRVYIHPF acetate
  • Angiotensin Receptor,Inhibitor,Angiotensin II human,inhibit,Angiotensin II,Ang II,DRVYIHPF,Apoptosis,Angiotensin II human acetate
  • (2S,5S,8S,11S,14S,17S)-2-((1H-Imidazol-5-yl)methyl)-17-amino-5-((S)-sec-butyl)-1-((S)-2-(((S)-1-carboxy-2-phenylethyl)carbamoyl)pyrrolidin-1-yl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-isopropyl-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazanonadecan-19-oic acid xacetic acid
  • 68521-88-0
  • C52H75N13O14
  • C50H71N13O12xC2H4O2
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