ChemicalBook > CAS DataBase List > 1-(5-Chloro-2-hydroxyphenyl)ethanone

1-(5-Chloro-2-hydroxyphenyl)ethanone

Product Name
1-(5-Chloro-2-hydroxyphenyl)ethanone
CAS No.
1450-74-4
Chemical Name
1-(5-Chloro-2-hydroxyphenyl)ethanone
Synonyms
1-(5-CHLORO-2-HYDROXYPHENYL)ETHAN-1-ONE;5-CHLORO-2-HYDROXYACETOPHENONE;1-(3-chlorophenyl)-2-hydroxyethan-1-one;AKOS BB-6937;ASISCHEM D38764;SALOR-INT L497495-1EA;2-Acetyl-4-chlorophenol;oro-2'-hydroxyacetophenone;2'-hydroxy-5'-chlorophenone;2-HYDROXY-5-CHLORO ACETOPHENONE
CBNumber
CB3482191
Molecular Formula
C8H7ClO2
Formula Weight
170.59
MOL File
1450-74-4.mol
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1-(5-Chloro-2-hydroxyphenyl)ethanone Property

Melting point:
54-56 °C(lit.)
Boiling point:
126-128 °C28 mm Hg(lit.)
Density 
1.2315 (rough estimate)
refractive index 
1.5590 (estimate)
Flash point:
107-109°C/12mm
storage temp. 
Sealed in dry,Room Temperature
pka
9.72±0.18(Predicted)
BRN 
1365589
InChIKey
XTGCUDZCCIRWHL-UHFFFAOYSA-N
CAS DataBase Reference
1450-74-4(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(5-chloro-2-hydroxyphenyl)-(1450-74-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29147000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
383384
Product name
5′-Chloro-2′-hydroxyacetophenone
Purity
99%
Packaging
5g
Price
$10.88
Updated
2024/03/01
Sigma-Aldrich
Product number
383384
Product name
5′-Chloro-2′-hydroxyacetophenone
Purity
99%
Packaging
25g
Price
$28.08
Updated
2024/03/01
Alfa Aesar
Product number
A15448
Product name
5'-Chloro-2'-hydroxyacetophenone, 99%
Packaging
5g
Price
$26.1
Updated
2022/04/27
Alfa Aesar
Product number
A15448
Product name
5'-Chloro-2'-hydroxyacetophenone, 99%
Packaging
1g
Price
$12.2
Updated
2021/12/16
TRC
Product number
C381338
Product name
1-(5-Chloro-2-hydroxyphenyl)ethanone
Packaging
500mg
Price
$45
Updated
2021/12/16
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1-(5-Chloro-2-hydroxyphenyl)ethanone Chemical Properties,Usage,Production

Chemical Properties

slightly yellow crystalline powder or chunks

Uses

5′-Chloro-2′-hydroxyacetophenone (5-chloro-2- hydroxyacetophenone) may be used in the synthesis of:

  • 6-chloro-2-methyl-4H-chrome-4-one
  • 1-(2-hydroxyphenyl)-5-phenyl-2,4-pentadien-1-ones
  • 1-(2-hydroxyphenyl)-5-phenyl-2,4-pentadien-1-ones
  • 2-styrenyl allyl ether

Preparation

Preparation by Fries rearrangement of 4-chlorophenyl acetate with aluminium chloride without solvent between 110° and 200°(90–100% yield).

General Description

5′-Chloro-2′-hydroxyacetophenone (5-chloro-2- hydroxyacetophenone) on condensation with salicylhydrazide yields Schiff base, which is reported to form copper(II) complexes. Dipole moment of 5-chloro-2- hydroxyacetophenone has been evaluated in benzene solution.

1-(5-Chloro-2-hydroxyphenyl)ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(5-Chloro-2-hydroxyphenyl)ethanone Suppliers

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View Lastest Price from 1-(5-Chloro-2-hydroxyphenyl)ethanone manufacturers

Honest Joy Holdings Limited
Product
5'-Chloro-2'-hydroxyacetophenone 1450-74-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99.1%
Supply Ability
100 tons
Release date
2022-01-26
Career Henan Chemical Co
Product
1-(5-Chloro-2-hydroxyphenyl)ethanone 1450-74-4
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2018-12-24

1450-74-4, 1-(5-Chloro-2-hydroxyphenyl)ethanoneRelated Search:

6-CHLOROCHROMAN-4-ONE 6,8-DICHLORO-3-FORMYLCHROMONE 5-Chloro-2-hydroxybenzophenone (+)-Griseofulvin 1-(5-Chloro-2-hydroxyphenyl)ethanone 3',5'-DICHLORO-2'-HYDROXYACETOPHENONE 2-AMINO-6-CHLORO-3-FORMYLCHROMONE MECLOCYCLINE SULFOSALICYLATE SALT Demeclocycline hydrochloride 5-CHLORO-BENZOFURAN-3-ONE Chlortetracycline hydrochloride 5-CHLORO-2-HYDROXY-4-METHYLBENZOPHENONE 1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone,1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone, 5-Chloro-3-bromo-2-hydroxyacetophenone 2-Chloro-3',4'-dihydroxyacetophenone 2-BROMO-1-(5-CHLORO-2-HYDROXYPHENYL)ETHANONE 1-(2-Chloro-6-hydroxyphenyl)ethanone 2'-Chloro-4'-hydroxyacetophenone 1-(4-CHLORO-2-HYDROXYPHENYL)ETHANONE

  • JRH-01003, 1-(5-Chloro-2-hydroxyphenyl)ethanone, 97%
  • SALOR-INT L497495-1EA
  • 2-Acetyl-4-chlorophenol
  • 5'-Chloro-2'-Hydroxy Acetophenone 2'-Hydorxy-5'-Chloro Acetophenone
  • 2'-Hydorxy-5'-ChloroAcetophenone
  • Acetophenone, 5'-chloro-2'-hydroxy-
  • Acetophenone,5-chloro-2-hydroxy-
  • 5'-Chloro-2'-hydroxyacetophenone,99%
  • Ethanone,1-(5-chloro-2-hydroxyphenyl)-
  • 1-(3-chlorophenyl)-2-hydroxyethan-1-one
  • ASISCHEM D38764
  • 2'-HYDROXY-5'-CHLORO ACETOPHENONE
  • 2-HYDROXY-5-CHLORO ACETOPHENONE
  • 1-(5-CHLORO-2-HYDROXYPHENYL)-1-ETHANONE
  • 1-(5-CHLORO-2-HYDROXYPHENYL)ETHAN-1-ONE
  • 1-(5-CHLORO-2-HYDROXYPHENYL)ETHANONE
  • AKOS BB-6937
  • 5'-CHLORO-2'-HYDROXYACETOPHENONE
  • 5-CHLORO-2-HYDROXYACETOPHENONE
  • 5'-Chloro-2'-hydroxyacetophenone 99%
  • 5'-Chloro-2'-hydroxyacetophenone, 98%+
  • oro-2'-hydroxyacetophenone
  • 2'-hydroxy-5'-chlorophenone
  • 1-(5 CHOLRO-2-HYDROXYPHENYL)ETHANONE
  • 2-HYDROXY-5-CHLOROACETOPHENONE -99+% CA
  • 2 HYDROXY-5-CHLOROACETOPHENONE-99+%
  • 5'-Chloro-2'-hydroxyacetophenone
  • 1450-74-4
  • ClC6H3OHCOCH3
  • Organic Building Blocks
  • Ketones
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Aromatic Acetophenones & Derivatives (substituted)
  • Phenoles and thiophenoles
  • Adehydes, Acetals & Ketones
  • Chlorine Compounds
  • Phenols
  • C7 to C8
  • Carbonyl Compounds
  • Ketones