ChemicalBook > CAS DataBase List > SB 269970 HYDROCHLORIDE

SB 269970 HYDROCHLORIDE

Product Name
SB 269970 HYDROCHLORIDE
CAS No.
201038-74-6
Chemical Name
SB 269970 HYDROCHLORIDE
Synonyms
CS-776;SB269970HCl;SB-269970;SB 269970;SB 269970 hydrochlor;SB269970 (SB-269970A);SB 269970 HYDROCHLORIDE;(R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol;Phenol, 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]-;(R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine;Pyrrolidine, 1-((3-hydroxyphenyl)sulfonyl)-2-(2-(4-methyl-1-piperidinyl)ethyl)-, (R)-
CBNumber
CB3490266
Molecular Formula
C18H28N2O3S
Formula Weight
352.49
MOL File
201038-74-6.mol
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SB 269970 HYDROCHLORIDE Property

Boiling point:
512.9±56.0 °C(Predicted)
Density 
1.188
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: 22 mg/mL
form 
solid
pka
8.88±0.10(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1612
Product name
SB-269970 hydrochloride
Purity
≥98%(HPLC)
Packaging
10
Price
$225
Updated
2021/12/16
Tocris
Product number
1612
Product name
SB-269970 hydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$933
Updated
2021/12/16
TRC
Product number
S155005
Product name
SB269970
Packaging
25mg
Price
$305
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008953
Product name
(2R)-1-[(3-HYDROXYPHENYL)SULFONYL]-2 -(2-(4-METHYL-1-PIPERIDINYL)ETHYL)PYRROLIDINE
Purity
95.00%
Packaging
10MG
Price
$721.59
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008953
Product name
(2R)-1-[(3-HYDROXYPHENYL)SULFONYL]-2 -(2-(4-METHYL-1-PIPERIDINYL)ETHYL)PYRROLIDINE
Purity
95.00%
Packaging
50MG
Price
$1327.97
Updated
2021/12/16
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SB 269970 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

SB 269970 is a selective and potent SR-7 antagonist.

Definition

ChEBI: 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]phenol is a sulfonamide.

Biological Activity

Potent and selective 5-HT 7 receptor antagonist (pK i values are 8.9, 7.2 and 6.0 for 5-HT 7A , 5-HT 5A and 5-HT 1B and < 6.0 for 5-HT 1A , 5-HT 1D , 5-HT 1E , 5-HT 1F , 5-HT 2A , 5-HT 2B , 5-HT 2C , 5-HT 4 and 5-HT 6 receptors respectively). Brain penetrant in vivo .

SB 269970 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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SB 269970 HYDROCHLORIDE Suppliers

China 58 Europe 1 Germany 2 Switzerland 1 The Netherlands 1 United Kingdom 1 United States 7 Global 71
3B Pharmachem (Wuhan) International Co.,Ltd.
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201038-74-6, SB 269970 HYDROCHLORIDERelated Search:

Dimethylamine hydrochloride SB216763 Sb-742457 MMP-2/MMP-9 INHIBITOR IV SB 242084 (hydrochloride) SB 415286 SB 202190 SB 431542 5-[2-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-1H-inden-1-one oxime SB1317 6-[2-tert-Butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline 4'-CHLORO-3-METHOXYCINNAMANILIDE SB-705498 SB 203580 SB242235 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride Ispinesib SB 269970 HYDROCHLORIDE

  • CS-776
  • SB-269970;SB 269970
  • SB 269970 HYDROCHLORIDE
  • SB269970HCl
  • (2R)-1-[(3-HYDROXYPHENYL)SULFONYL]-2-[2-(4-METHYL-1-PIPERIDINYL)ETHYL]PYRROLIDINE HYDROCHLORIDE
  • Pyrrolidine, 1-((3-hydroxyphenyl)sulfonyl)-2-(2-(4-methyl-1-piperidinyl)ethyl)-, (R)-
  • (R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine
  • (R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol
  • Phenol, 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]-
  • SB 269970 hydrochlor
  • SB269970 (SB-269970A)
  • 201038-74-6
  • Serotonin receptor