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HUMULONE

Product Name
HUMULONE
CAS No.
26472-41-3
Chemical Name
HUMULONE
Synonyms
HUMULONE;α-bitter acid;[R,(-)]-Humulone;HUMULONE USP/EP/BP;Humulon,alpha-Humulon;Phloroglucinol Impurity T;(R)-Humulone DISCONTINUED;α-Bitter acid, α-Lupulic acid;Humulone, mixture of homologues;(6R)-4,6-Diprenyl-3,5,6-trihydroxy-2-(1-oxo-3-methylbutyl)-2,4-cyclohexadiene-1-one
CBNumber
CB3497674
Molecular Formula
C21H30O5
Formula Weight
362.46
MOL File
26472-41-3.mol
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HUMULONE Property

Melting point:
65-66.5℃
alpha 
D20 -212° (1.0 g in 15.5 g 96% alc)
Boiling point:
414.06°C (rough estimate)
Density 
1.157±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 
1.6120 (estimate)
storage temp. 
−20°C
solubility 
DMSO : 100 mg/mL (275.89 mM; Need ultrasonic)
form 
Powder
pka
4.50±1.00(Predicted)
color 
Light yellow to yellow
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Safety

WGK Germany 
3
F 
10-23
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FH65574
Product name
Humulone
Packaging
200ug
Price
$160
Updated
2021/12/16
Biosynth Carbosynth
Product number
FH65574
Product name
Humulone
Packaging
500ug
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FH65574
Product name
Humulone
Packaging
1mg
Price
$450
Updated
2021/12/16
Biosynth Carbosynth
Product number
FH65574
Product name
Humulone
Packaging
2mg
Price
$550
Updated
2021/12/16
Biosynth Carbosynth
Product number
FH65574
Product name
Humulone
Packaging
5mg
Price
$700
Updated
2021/12/16
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HUMULONE Chemical Properties,Usage,Production

Uses

(R)-Humulone (CAS# 26471-41-3) can be used as a chemosensory receptor ligand.

Definition

ChEBI: Humulone is an optically active cyclic ketone consisting of 3,5,6-trihydroxycyclohexa-2,4-dien-1-one bearing two 3-methylbut-2-en-1-yl substituents at positions 4 and 6 as well as a 3-methylbutanoyl group at the 2-position. It has a role as an antibacterial drug, an antioxidant, a cyclooxygenase 2 inhibitor and a metabolite. It is a diketone, a triol, a cyclic ketone, an aromatic ketone and a tertiary alpha-hydroxy ketone.

target

IL Receptor | AP-1 | COX | p65 | NF-kB | IkB | VEGFR | Antifection | IKK

Purification Methods

Crystallise humulon from Et2O. It dissolves slightly in hot H2O but precipitates on cooling. It has max () 237 (13,760) and 282 (8,330) in EtOH. [Wollmer Chem Ber 49 780 1916, Carson J Am Chem Soc 73 4652 1951, Beilstein 8 II 537, 8 III 4034, 8 IV 3410.]

HUMULONE Preparation Products And Raw materials

Raw materials

Preparation Products

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HUMULONE Suppliers

China 37 India 1 Switzerland 1 United Kingdom 2 United States 6 USA 1 Global 48
EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
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info@emmx.com
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BOC Sciences
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+1-631-485-4226
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1-631-614-7828
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inquiry@bocsci.com
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Aladdin Scientific
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+1-+1(833)-552-7181
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sales@aladdinsci.com
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Alfa Chemistry
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Quality Phytochemicals LLC
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sales@qualityphytochemicalsllc.com
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United States
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INDOFINE Chemical Company, Inc.
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chemical@indofinechemical.com
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United States
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6176
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26472-41-3, HUMULONERelated Search:

ISOXANTHOHUMOL alpha-Cyperone beta-Sitosterol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Asiaticoside B poricoic acid B bakkenolide A SWERTIANOLIN APIGENIN 6-GLUCOSYL-7-O-METHYL ETHER Jaceosidin Polygalasaponin XXXI GARDENOSIDE dichotomitin caesalpin J HARRINGTONINE Isoastragaloside II poricoic acid A 3-methyl ester Poricoic acid A(F)

  • (6S)-3,5,6-trihydroxy-2-(3-methylbutanoyl)-4,6-bis(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one
  • (6R)-3,5,6-trihydroxy-2-isovaleryl-4,6-bis(3-methylbut-2-enyl)cyclohexa-2,4-dienone
  • α-bitter acid
  • Humulone, mixture of homologues
  • α-Bitter acid, α-Lupulic acid
  • (6R)-2-(3-Methylbutyryl)-3,5,6-trihydroxy-4,6-bis(3-methyl-2-butenyl)-2,4-cyclohexadiene-1-one
  • (6R)-4,6-Diprenyl-3,5,6-trihydroxy-2-(1-oxo-3-methylbutyl)-2,4-cyclohexadiene-1-one
  • [R,(-)]-3,5,6-Trihydroxy-4,6-bis(3-methyl-2-butenyl)-2-(3-methyl-1-oxobutyl)-2,4-cyclohexadien-1-one
  • [R,(-)]-Humulone
  • HUMULONE
  • 2,4-Cyclohexadien-1-one,3,5,6-trihydroxy-4,6-bis(3-methyl-2-buten-1-yl)-2-(3-methyl-1-oxobutyl)-, (6R)-
  • HUMULONE USP/EP/BP
  • (R)-Humulone DISCONTINUED
  • Phloroglucinol Impurity T
  • (R)-3,5,6-Trihydroxy-4,6-bis(3-methylbut-2-en-1-yl)-2-(3-methylbutanoyl)cyclohexa-2,4-dienone
  • Humulon,alpha-Humulon
  • 26472-41-3
  • Miscellaneous Natural Products