ChemicalBook > CAS DataBase List > Rabeprazole

Rabeprazole

Product Name
Rabeprazole
CAS No.
117976-89-3
Chemical Name
Rabeprazole
Synonyms
Rebeprazole;CS-1363;NSC24156;ly-307640;NSC 24156;NSC-24156;RABEPRAZOLE;Rabeprazole USP/EP/BP;Rabeprazole-IP/USP/IHS;Rabeprazole, LY 307640
CBNumber
CB3680731
Molecular Formula
C18H21N3O3S
Formula Weight
359.44
MOL File
117976-89-3.mol
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Rabeprazole Property

Melting point:
99-100° (dec)
Boiling point:
603.9±65.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.57±0.10(Predicted)
color 
Light Brown to Very Dark Brown
BCS Class
1,3
Stability:
Hygroscopic
CAS DataBase Reference
117976-89-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26-37/39
Hazardous Substances Data
117976-89-3(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
R070540
Product name
Rabeprazole
Packaging
500mg
Price
$875
Updated
2021/12/16
Biosynth Carbosynth
Product number
IM57864
Product name
Rabeprazole
Packaging
10g
Price
$550
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
61545
Product name
Rabeprazole
Packaging
50mg
Price
$610
Updated
2021/12/16
ApexBio Technology
Product number
B3467
Product name
Rabeprazole
Packaging
10mM(in 1mL DMSO)
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
IM57864
Product name
Rabeprazole
Packaging
2g
Price
$180
Updated
2021/12/16
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Rabeprazole Chemical Properties,Usage,Production

Description

Rabeprazole, a proton pump inhibitor (PPI), effectively lowers stomach acid production to alleviate conditions such as gastroesophageal reflux disease (GERD), ulcers, and other issues caused by excessive acid production. It belongs to the benzimidazole derivative family, sharing a structural similarity with omeprazole, another PPI. Rabeprazole hampers the activity of the gastric proton pump responsible for acid production. By binding to the pump, it obstructs the release of hydrogen ions into the stomach, ultimately reducing acid production. Furthermore, rabeprazole exhibits various biochemical and physiological effects. A study conducted on rats revealed that rabeprazole effectively decreases the gastric proton pump′s activity, leading to a decrease in gastric acid secretion.

Uses

Rabeprazole is used to treat hyperacidity. It is a proton pump inhibitor that helps heal gastrointestinal ulcers, treats gastroesophageal reflux disease, and also treats hypersecretory disorders.

Definition

ChEBI: Rabeprazole is a member of benzimidazoles, a sulfoxide and a member of pyridines. It has a role as an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor and an anti-ulcer drug. It is a conjugate acid of a rabeprazole(1-).

brand name

Aciphex (Eisai Medical Research) .

Side effects

The more common side effects of rabeprazole can include: headache. pain in the abdomen (stomach area) sore throat.
The serious side effects of rabeprazole can include: has stomach cramps, bloated feeling, watery and severe diarrhea which may also be bloody sometimes, fever, nausea or vomiting, or unusual tiredness or weakness. This medicine may increase your risk of having fractures of the hip, wrist, and spine.

Dosage

Rabeprazole is usually taken once a day. Follow all directions on the prescription label and read all dosing instructions or instruction sheets. Use the medication exactly as directed.Rabeprazole is only suitable for short-term use, usually 4 to 8 weeks. If you need additional treatment time, your doctor may recommend a second course of treatment.

Rabeprazole Preparation Products And Raw materials

Raw materials

Preparation Products

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Rabeprazole Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8850
Advantage
52
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6818
Advantage
65
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
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View Lastest Price from Rabeprazole manufacturers

Sinoway Industrial co., ltd.
Product
Rabeprazole 117976-89-3
Price
US $6.00-0.60/G/Bag
Min. Order
1G/Bag
Purity
99% up, High Density
Supply Ability
20 tons
Release date
2023-12-25
Shaanxi Dideu Medichem Co. Ltd
Product
Rabeprazole 117976-89-3
Price
US $1.00-1.00/Kg/Bag
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-30
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Rabeprazole 117976-89-3
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kg
Release date
2021-11-02

117976-89-3, RabeprazoleRelated Search:


  • 2-[[4-(3-methoxypropoxy)-3-methyl-pyridin-2-yl]methylsulfinyl]-1h-benzoimidazole
  • 2-[[(3-METHYL-4-(3-METHOXYPROPOXY)-2-PYRIDINYL)METHYL]SULPHINYL]-1H-BENZIMIDAZOLE
  • 2-(CHOLROMETHYL)-4-(3-METHOXYPROPOXY)-3-METHYLPYRIDINE
  • ly-307640
  • 1H-Benzimidazole,2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-
  • 1H-1,3-benzimidazol-2-yl [4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl sulfoxide-sodium salt
  • 2-[[[3-Methyl-4-(3-methoxypropoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
  • 2-[[[4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]-1H-benzimidazole
  • 2-[3-Methyl-4-(3-methoxypropoxy)-2-pyridinylmethylsulfinyl]-1H-benzimidazole
  • Rebeprazole
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  • 2-(((4-(3-Methoxypropoxy)-3-Methylpyridin-2-yl)Methyl)sulfinyl)-1H-benzo[d]iMidazole
  • Rabeprazole Sodium (200 mg) (Sodium 2-[(R)-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]benzimidazol-1-ide hydrate)
  • RABEPRAZOLE
  • CS-1363
  • Rabeprazole, LY 307640
  • 2-({[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methane}sulfinyl)-1H-1,3-benzodiazole
  • Rabeprazole USP/EP/BP
  • 2-[[(4-(3-Methoxypropoxy)- 3-methyl-2-pyridinyl)-2- methyl]sulfinyl] -1H-benzimidazole
  • Rabeprazole-IP/USP/IHS
  • NSC 24156
  • NSC24156
  • NSC-24156
  • Diclofop Impurity 10 (Diclocymet)
  • RABEPRAZOLE 6.25%, 6.89%, 8.5%, 13.33%, 15%, 22.5% PELLETS
  • 117976-89-3
  • 117986-89-3
  • C18H21N3O3S
  • Rabeprazole
  • API's
  • Active Pharmaceutical Ingredients
  • APIs