5-Bromo-1-tetralone

Product Name: 5-Bromo-1-tetralone
CAS No.: 68449-30-9
Chemical Name: 5-Bromo-1-tetralone
Synonyms: 5-BROMOTETRALONE;5-BROMO-1-TETRALONE;5-Bromo-tetral-1-on;5-BROMO-A-TETRALONE;5-bromotetralin-1-one;5-broMo-1,2,3,4-tetrahy;5-Bromo-1-tetralone?New;5-Bromo-3,4-dihydro-2H-naphthalen-1-one;5-BROMO-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE;5-BROMO-3,4-DIHYDRO-1(2H)-NAPHTHALENONE
CBNumber: CB3700428
Molecular Formula: C10H9BrO
Formula Weight: 225.08
MOL File: 68449-30-9.mol

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5-Bromo-1-tetralone Property

Melting point:: 47-48 °C(Solv: methanol (67-56-1))
Boiling point:: 105-110 °C(Press: 0.3 Torr)
Density: 1.511±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): .15 mg/ml
form: A crystalline solid
color: Yellow to brown
InChI: InChI=1S/C10H9BrO/c11-9-5-1-4-8-7(9)3-2-6-10(8)12/h1,4-5H,2-3,6H2
InChIKey: DMXOUYZZHVHEQR-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C(Br)=CC=C2)CCC1
CAS DataBase Reference: 68449-30-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
HS Code: 2909309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10007134
Product name: 5-Bromotetralone
Purity: >98%
Packaging: 50mg
Price: $12
Updated: 2023/01/06

Cayman Chemical

Product number: 10007134
Product name: 5-Bromotetralone
Purity: >98%
Packaging: 100mg
Price: $21
Updated: 2023/01/06

Cayman Chemical

Product number: 10007134
Product name: 5-Bromotetralone
Purity: >98%
Packaging: 250mg
Price: $46
Updated: 2024/03/01

Cayman Chemical

Product number: 10007134
Product name: 5-Bromotetralone
Purity: >98%
Packaging: 500mg
Price: $74
Updated: 2024/03/01

TRC

Product number: B415330
Product name: 5-Bromo-1-tetralone
Packaging: 100mg
Price: $45
Updated: 2021/12/16

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5-Bromo-1-tetralone Chemical Properties,Usage,Production

Description

5-Bromotetralone is a synthetic intermediate useful for pharmaceutical synthesis.

Uses

5-Bromotetralone (5-Bromo-3,4-dihydro-2H-naphthalen-1-one) is a synthetic intermediate useful for pharmaceutical synthesis.

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 4226, 1984 DOI: 10.1021/jo00196a024

Synthesis

529-34-0

32281-97-3

68449-30-9

7-Bromo-3,4-dihydro-2H-1-naphthalenone and 5-bromo-1-tetrahydronaphthalenone were synthesized using 1-tetralone as starting material with reference to the methodology reported by Cornelius, L.A.M. and Combs, D.W. in Synthetic Communications 1994, 24, 2777-2788. The procedure was as follows: the isomers in the reaction mixture were separated by silica gel fast chromatography (using a Biotage Flash 75 system with an elution solvent ratio of 20:1 hexane/methyl tert-butyl ether) to afford 5-bromo-1-tetralone (11.59 g, 51% yield) and 7-bromo-1-tetralone (9.45 g, 42% yield), respectively.

References

[1] Patent: WO2005/95326, 2005, A2. Location in patent: Page/Page column 110-111
[2] Patent: WO2004/94384, 2004, A2. Location in patent: Page 63-64
[3] Patent: WO2004/94413, 2004, A1. Location in patent: Page 63-64
[4] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 1, p. 29 - 35
[5] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 16, p. 4405 - 4409

5-Bromo-1-tetralone Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-1-tetralone Suppliers

China 119 Germany 1 India 2 Switzerland 1 United Kingdom 5 United States 19 Global 147

Service Chemical Inc.

Tel: --
Fax: --
Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

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View Lastest Price from 5-Bromo-1-tetralone manufacturers

Henan Fengda Chemical Co., Ltd

Product: 5-Bromo-3,4-dihydro-1(2H)-naphthalenone 68449-30-9
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-31

Shanghai Rlavie Technology Co ltd

Product: 5-Bromo-1-tetralone 68449-30-9
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%minHPLC
Supply Ability: 50kgs/month
Release date: 2021-11-14

Career Henan Chemical Co

Product: 5-Bromo-1-tetralone 68449-30-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-24

68449-30-9, 5-Bromo-1-tetraloneRelated Search:

3-Bromoanisole Dihydromyrcenol 4'-Bromoacetophenone 1-Bromonaphthalene 2-Bromoacetophenone Decahydronaphthalene 1-Tetralone Nabumetone 1,2,3,4-Tetrahydronaphthalene beta-Tetralone Bromine 6-BROMO-2-TETRALONE 98%,6-Bromo-2-tetralone, 98 %,6-BROMO-2-TETRALONE 5,7-dibromo-2-tetralone 5-BROMO-2-TETRALONE 7-BROMO-1-TETRALONE,7-BROMO-ALPHA-TETRALONE,7-bromo-à-tetralone 7-BROMO-2-TETRALONE 8-Bromo-1-tetralone,8-Bromo-α-Tetralone 2-Bromo-1-tetralone

5-BROMO-1-TETRALONE

5-BROMOTETRALONE

5-BROMO-3,4-DIHYDRO-1(2H)-NAPHTHALENONE

5-BROMO-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE

5-Bromo-3,4-dihydro-2H-naphthalen-1-one

5-BROMO-A-TETRALONE

5-broMo-1,2,3,4-tetrahydronaphthalen-1-one

5-Bromo-1-tetralone, 5-Bromo-1-oxo-1,2,3,4-tetrahydronaphthalene

5-Bromo-tetral-1-on

5-broMo-1,2,3,4-tetrahy

1(2H)-Naphthalenone, 5-bromo-3,4-dihydro-

5-bromotetralin-1-one

5-Bromo-1-tetralone?New

68449-30-9

Benzocycles

CHIRAL CHEMICALS