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L-Histidine hydrochloride

Uses
Product Name
L-Histidine hydrochloride
CAS No.
1007-42-7
Chemical Name
L-Histidine hydrochloride
Synonyms
histidine hydrochloride;His HCl;H-His-OH.xHCl;Crystalline2HCl;L-Histidine hydrochloride;L-Histdine Dihydrochloride;L-HISTIDINE DIHYDROCHLORIDE;L-Histidine, hydrochloride (1:x);L-Histidine hydrochloride solution;L-Histidine hydrochloride CAS NO.1007-42-7
CBNumber
CB3714676
Molecular Formula
C6H10ClN3O2
Formula Weight
191.62
MOL File
1007-42-7.mol
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L-Histidine hydrochloride Property

Melting point:
240-245 °C (dec.)
alpha 
[α]D20 +7.0~+10.0°(c=2,HCl)
storage temp. 
Inert atmosphere,Room Temperature
Appearance
White to off-white Solid
InChI
InChI=1/C6H9N3O2.ClH/c7-5(6(10)11)1-4-2-8-3-9-4;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H/t5-;/s3
InChIKey
QZNNVYOVQUKYSC-USHJBNIQNA-N
SMILES
C(C1N=CNC=1)[C@H](N)C(=O)O.Cl |&1:6,r|
CAS DataBase Reference
1007-42-7(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
RIDADR 
UN 1789 8/PG 3
WGK Germany 
3
3-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
135005
Product name
(2S)-2-Amino-3-(1H-imidazol-4-yl)-propanoicacidhydrochloride
Purity
95%+
Packaging
1g
Price
$195
Updated
2021/12/16
Matrix Scientific
Product number
135005
Product name
(2S)-2-Amino-3-(1H-imidazol-4-yl)-propanoicacidhydrochloride
Purity
95%+
Packaging
2.500g
Price
$420
Updated
2021/12/16
Matrix Scientific
Product number
135005
Product name
(2S)-2-Amino-3-(1H-imidazol-4-yl)-propanoicacidhydrochloride
Purity
95%+
Packaging
5g
Price
$636
Updated
2021/12/16
Ambeed
Product number
A138210
Product name
H-His-OH.xHCl
Purity
97%
Packaging
10g
Price
$5
Updated
2021/12/16
Ambeed
Product number
A138210
Product name
H-His-OH.xHCl
Purity
97%
Packaging
25g
Price
$7
Updated
2021/12/16
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L-Histidine hydrochloride Chemical Properties,Usage,Production

Uses

Amino acid drugs, the main component of amino acid infusions and comprehensive amino acid preparations; used as an adjunct treatment for peptic ulcers. Also used for cardiovascular diseases such as anemia, aortitis, and heart failure; a nutritional supplement, as the body synthesizes amino acids slowly, making them quasi-essential amino acids, which can be used to fortify infant formula and post-surgical patient food.

Purification Methods

The dihydrochloride crystallises from water or aqueous EtOH and is washed with acetone, then diethyl ether. Alternatively convert it to the histidine di-(3,4-dichlorobenzenesulfonate) salt by dissolving 3,4-dichlorobenzenesulfonic acid (1.5g/10mL) in the aqueous histidine solution with warming, and then the solution is cooled in ice. The resulting crystals (m 280o dec) can be recrystallised from 5% aqueous 3,4-dichlorobenzenesulfonic acid, then dried over CaCl2 under vacuum, and washed with diethyl ether to remove Purification of Biochemicals — Amino Acids and Peptides excess reagent. The dihydrochloride can be regenerated by passing the solution through a Dowex-1 (Cl-form) ion-exchange column. The solid is obtained by evaporation of the solution on a steam bath or better in a vacuum. [Greenstein & Winitz, The Amino Acids Vol 3 p 1976 1961, Beilstein 25/16 V 366.]

L-Histidine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from L-Histidine hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
L-Histidine hydrochloride 1007-42-7
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%-101%;AJI92
Supply Ability
1000kg
Release date
2021-08-19
Hebei Chuanghai Biotechnology Co., Ltd
Product
L-Histidine hydrochloride 1007-42-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-05
Wuhan Boyuan Import & Export Co., LTD
Product
L-Histidine hydrochloride CAS NO.1007-42-7 1007-42-7
Price
US $1.00/G
Min. Order
100G
Purity
99.9%
Supply Ability
50000 tons
Release date
2018-11-06

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