ChemicalBook > CAS DataBase List > 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER

2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER

Product Name: 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER
CAS No.: 197376-47-9
Chemical Name: 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER
Synonyms: Ethyl 2-Chloropyridine-5-acetate;Ethyl 6-Chloropyridine-3-acetate;2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL;ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE;Ethyl 2-(6-chloropyridin-3-yl)acetate;2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER;6-Chloro-3-pyridineacetic acid ethyl ester;3-Pyridineacetic acid, 6-chloro-, ethyl ester;2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER ISO 9001：2015 REACH
CBNumber: CB3758232
Molecular Formula: C9H10ClNO2
Formula Weight: 199.63
MOL File: 197376-47-9.mol

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2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER Property

Boiling point:: 285.8±25.0 °C(Predicted)
Density: 1.217±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -0.34±0.10(Predicted)
Appearance: Colorless to light yellow Liquid
InChI: InChI=1S/C9H10ClNO2/c1-2-13-9(12)5-7-3-4-8(10)11-6-7/h3-4,6H,2,5H2,1H3
InChIKey: HNMKCAOYIPYXRD-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=CC=C1CC(OCC)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B126528
Product name: ethyl2-(6-chloropyridin-3-yl)acetate
Packaging: 50mg
Price: $110
Updated: 2021/12/16

AK Scientific

Product number: J52123
Product name: 2-Chloropyridine-5-aceticacidethylester
Packaging: 1g
Price: $100
Updated: 2021/12/16

AK Scientific

Product number: J52123
Product name: 2-Chloropyridine-5-aceticacidethylester
Packaging: 10g
Price: $500
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0319598
Product name: 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER
Purity: 95.00%
Packaging: 5MG
Price: $505.15
Updated: 2021/12/16

Ambeed

Product number: A110060
Product name: Ethyl6-Chloropyridine-3-acetate
Purity: 95%
Packaging: 250mg
Price: $27
Updated: 2021/12/16

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2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

64-17-5

39891-13-9

197376-47-9

The general procedure for the synthesis of ethyl 2-(6-chloropyridin-3-yl)acetate from ethanol and 2-chloropyridine-5-acetic acid was as follows: to an ethanolic solution of 6-chloro-3-pyridineacetic acid (1 g, 5.83 mmol) was slowly added concentrated sulfuric acid (1.6 mL). The reaction mixture was heated to reflux and kept for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated in a rotary evaporator to remove most of the ethanol. The concentrated residue was dissolved in ethyl acetate and subsequently washed with saturated sodium bicarbonate solution to neutralize the residual acid. The organic phase was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give the crude product. Finally, the crude product was purified by silica gel column chromatography to afford ethyl 2-(6-chloropyridin-3-yl)acetate (1.1 g, 95% yield).

References

[1] Patent: WO2013/13817, 2013, A1. Location in patent: Page/Page column 99
[2] Patent: WO2013/13815, 2013, A1. Location in patent: Page/Page column 147
[3] Patent: US2013/29961, 2013, A1. Location in patent: Paragraph 0664
[4] Patent: US2013/29962, 2013, A1. Location in patent: Paragraph 0815
[5] Chemical Communications, 2015, vol. 51, # 84, p. 15446 - 15449

2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER manufacturers

Dideu Industries Group Limited

Product: 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL 197376-47-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-06

Career Henan Chemical Co

Product: 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER 197376-47-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-09

197376-47-9, 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTERRelated Search:

6-CYANONICOTINIC ACID 3-(3-PYRIDYL)ACRYLIC ACID 4-(N,N-DIMETHYLAMINO)PHENYLBORONIC ACID, PINACOL ESTER 2-CYANO-3-PYRIDINECARBOXYLIC ACID METHYL ESTER 4-Ethoxy-5-nitro-α-chloropyridine-2-acetic acid ethyl ester α-Chloro-3-nitro-6-chloropyridine-2-acetic acid ethyl ester (6-CHLORO-PYRIDIN-3-YL)-OXO-ACETIC ACID ETHYL ESTER 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER ETHYL 3-PYRIDYLACETATE 3-Pyridylacetic acid methyl pyridine-3-acetate 2-CHLOROPYRIDINE-5-ACETIC ACID

Ethyl 2-(6-chloropyridin-3-yl)acetate

ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE

6-Chloro-3-pyridineacetic acid ethyl ester

2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER

3-Pyridineacetic acid, 6-chloro-, ethyl ester

Ethyl 6-Chloropyridine-3-acetate

2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER ISO 9001：2015 REACH

Ethyl 2-Chloropyridine-5-acetate

2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL

197376-47-9

pyridine series

Pyridine

Pyridines