ChemicalBook > CAS DataBase List > 3,5-Dichlorobenzoic acid

3,5-Dichlorobenzoic acid

Product Name
3,5-Dichlorobenzoic acid
CAS No.
51-36-5
Chemical Name
3,5-Dichlorobenzoic acid
Synonyms
3,5-dichlorobenzoic;3.5-Dichlorobe;BUTTPARK 45\07-34;RARECHEM AL BO 0040;3,5-DICHLOROBENZIC ACID;3,5-dichloro-benzoicaci;3,5-Dichlorbenzoesaeure;3,5-DICHLOROBENZOIC ACID;BENZOIC ACID, 3,5-DICHLORO-;3,5-Dichlorobenzoicacid,99%
CBNumber
CB3760057
Molecular Formula
C7H4Cl2O2
Formula Weight
191.01
MOL File
51-36-5.mol
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3,5-Dichlorobenzoic acid Property

Melting point:
184-187 °C (lit.)
Boiling point:
273.68°C (rough estimate)
Density 
1.4410 (rough estimate)
refractive index 
1.4590 (estimate)
storage temp. 
Sealed in dry,Room Temperature
pka
3.46±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
Water Solubility 
147.1mg/L(temperature not stated)
BRN 
2044776
InChI
InChI=1S/C7H4Cl2O2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,(H,10,11)
InChIKey
CXKCZFDUOYMOOP-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(Cl)=CC(Cl)=C1
CAS DataBase Reference
51-36-5(CAS DataBase Reference)
NIST Chemistry Reference
3,5-Dichlorobenzoic acid(51-36-5)
EPA Substance Registry System
3,5-Dichlorobenzoic acid (51-36-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
DG7350000
HazardClass 
IRRITANT
HS Code 
29163990
Toxicity
mouse,LD50,intraperitoneal,237mg/kg (237mg/kg),BEHAVIORAL: REGIDITYBEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY),Journal of Medicinal Chemistry. Vol. 11, Pg. 1020, 1968.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D57507
Product name
3,5-Dichlorobenzoic acid
Purity
97%
Packaging
25g
Price
$70.8
Updated
2024/03/01
TCI Chemical
Product number
D0341
Product name
3,5-Dichlorobenzoic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
D0341
Product name
3,5-Dichlorobenzoic Acid
Purity
>98.0%(T)
Packaging
500g
Price
$370
Updated
2024/03/01
Alfa Aesar
Product number
A15168
Product name
3,5-Dichlorobenzoic acid, 99%
Packaging
5g
Price
$36.65
Updated
2024/03/01
Alfa Aesar
Product number
A15168
Product name
3,5-Dichlorobenzoic acid, 99%
Packaging
25g
Price
$126.65
Updated
2024/03/01
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3,5-Dichlorobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

White to beige powder

Uses

3,5-Dichlorobenzoic acid is used in organic synthesis and pesticide and pharmaceutical intermediates. It can be used to synthesize 3,5-Dichloro-N-(4-hydroxyphenethyl)benzamide and (3,5-Dichlorophenyl)-(4-fluorophenyl)methanone.

Definition

ChEBI: 3,5-dichlorobenzoic acid is a chlorobenzoic acid that is benzoic acid in which the ring hydrogens at positions 3 and 5 are substituted by chloro groups. It has a role as a herbicide and a metabolite. It is a chlorobenzoic acid and a dichlorobenzene. It derives from a benzoic acid. It is a conjugate acid of a 3,5-dichlorobenzoate.

Preparation

Synthesis of 3,5-dichlorobenzoic acid: 200 parts of ethanol is slowly added to a solution, heated to 70°C, of the diazonium salt prepared as described in Example 1 from 412 parts of 3,5-dichloroanthranilic acid; elimination of nitrogen immediately takes place with evolution of heat. The mixture is stirred for another 15 minutes and 350 parts (92% of theory) of 3,5-dichlorobenzoic acid having a melting point of 176° to 178°C is isolated as described in Example 1.

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 455, 1951 DOI: 10.1021/ja01145a145

Purification Methods

Crystallise the acid from EtOH and sublime it in a vacuum. [Beilstein 9 IV 1008.] Aromatic acid impurities (to <0.05%) can be removed via the (±)--methylbenzylamine salt as described for 2,4-dichlorobenzoic acid [Ley & Yates Organic Process Research & Development 12 120 2008.]

3,5-Dichlorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Dicamba 3-Chlorobenzoic acid
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3,5-Dichlorobenzoic acid Suppliers

Americas 1 Belgium 3 China 288 Europe 3 France 1 Germany 8 India 23 Japan 4 Slovakia 1 South Korea 1 Switzerland 4 Ukraine 2 United Kingdom 21 United States 54 Global 414
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View Lastest Price from 3,5-Dichlorobenzoic acid manufacturers

Speranza Chemical Co., Ltd.
Product
3,5-Dichlorobenzoic acid 51-36-5
Price
US $20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
300MT/year
Release date
2021-02-03
Wuhan Boyuan Import & Export Co., LTD
Product
3,5-Dichlorobenzoic acid 51-36-5
Price
US $16.00-10.00/kg
Min. Order
1kg
Purity
99.50%
Supply Ability
10kg
Release date
2023-06-29
Honest Joy Holdings Limited
Product
3,5-Dichlorobenzoic acid 51-36-5
Price
US $0.00/KG
Min. Order
1KG
Purity
97.2%
Supply Ability
100 tons
Release date
2022-02-18

51-36-5, 3,5-Dichlorobenzoic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate 4-Nitrobenzoic acid Benzoic acid Estradiol benzoate 1,2-Dichloro-4-(chloromethyl)benzene 4-Aminobenzoic acid Citric acid Folic acid 4-Hydroxybenzoic acid Ascoric Acid 3,4-DICHLOROBENZOIC ACID ETHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Tetrachlorophthalic anhydride Chlorthal Dacthal 3,5-Dichloro-4-hydroxybenzoic acid METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 2,3-DICHLOROBENZOIC ACID

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  • 3,5- Dichlorobenzoic acid (DBA)
  • 3,5-Dichlorbenzoesaeure
  • 3,5-Pyrole Dicarboxalic acid
  • 51-36-5
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  • Carbonyl Compounds
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