ChemicalBook > CAS DataBase List > Budigalimab
Budigalimab
- Product Name
- Budigalimab
- CAS No.
- 2098225-93-3
- Chemical Name
- Budigalimab
- Synonyms
- Budigalimab;Budigalimab (anti-PD-1);Research Grade Budigalimab;Research Grade Budigalimab (DHH02210)
- CBNumber
- CB38081097
- Formula Weight
- 0
- MOL File
- Mol file
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Budigalimab Property
- form
- Liquid
- color
- Colorless to light yellow
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Budigalimab Chemical Properties,Usage,Production
Uses
Budigalimab (ABBV 181; PR 1648817) is a humanized, recombinant IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. Budigalimab has an Fc mutation that reduces the inhibition of Fc receptor interactions and effector factors. Budigalimab can block the binding of PD-1 and PD-L1, which has anti-tumor activity. Budigalimab can be used in the study of solid tumors[1].
References
[1] Powderly J, et al. Model Informed Dosing Regimen and Phase I Results of the Anti-PD-1 Antibody Budigalimab (ABBV-181). Clin Transl Sci. 2021 Jan;14(1):277-287. DOI:10.1111/cts.12855
Budigalimab Preparation Products And Raw materials
Raw materials
Preparation Products
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Budigalimab Suppliers
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