ChemicalBook > CAS DataBase List > Enoticumab
Enoticumab
- Product Name
- Enoticumab
- CAS No.
- 1192578-27-0
- Chemical Name
- Enoticumab
- Synonyms
- Enoticumab;Enoticumab (anti-DLL4);Research Grade Enoticumab;Research Grade Enoticumab (DHJ65302)
- CBNumber
- CB08080857
- Formula Weight
- 0
- MOL File
- Mol file
More
Less
Enoticumab Property
- form
- Liquid
- color
- Colorless to light yellow
More
Less
Enoticumab Chemical Properties,Usage,Production
Uses
Enoticumab (REGN421, SAR153192) is an IgG1κ antibody targeting human Dll4. DLL4 is a ligand of the Notch signaling pathway and regulates fatty acid uptake through non-transcriptional regulation of macropinocytosis-dependent long-chain fatty acid uptake. Specific in vivo activity of Enoticumab in an ovarian xenograft model. EGN421 (2.5 mg/kg once weekly) resulted in 86% and 83% tumor growth inhibition in mouse subcutaneous TOV-112D or intraperitoneal A2780 human tumor xenograft models, respectively[1].
References
[1] Kuhnert F, Chen G, Thurston G. Potent anti-tumor activity of blocking stromal Dll4 in ovarian xenograft models[J]. Cancer Research, 2013, 73(8_Supplement): 5091-5091.
Enoticumab Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Enoticumab Suppliers
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8000
- Advantage
- 62
- Tel
- 15817493340
- 981810490@qq.com
- Country
- China
- ProdList
- 1566
- Advantage
- 58
- Tel
- 027-65317797 15926423062
- Fax
- QQ:422450190
- 422450190@qq.com
- Country
- China
- ProdList
- 10308
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58
- Tel
- 027-65279366 18108604356
- products@biolabreagent.com
- Country
- China
- ProdList
- 9868
- Advantage
- 58
- Tel
- 13720134139 086-15871494362 13720134139
- orders@jknbiochem.com
- Country
- China
- ProdList
- 6762
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11973
- Advantage
- 58
- Tel
- 0731-13823398 15111215862
- 313359644@qq.com
- Country
- China
- ProdList
- 4161
- Advantage
- 58
- Tel
- 17316404525 17316404525
- 209533805@qq.com
- Country
- China
- ProdList
- 9763
- Advantage
- 58
1192578-27-0, EnoticumabRelated Search:
Siplizumab
h5G1.1-scFv
Research Grade Clivatuzumab (DHD14205)
Crovalimab
Ongericimab
Lanadelumab
Budigalimab
Tregalizumab
Nirsevimab
Sotevtamab