ChemicalBook > CAS DataBase List > 5-FLUORO-2-HYDROXYMETHYL PYRIDINE

5-FLUORO-2-HYDROXYMETHYL PYRIDINE

Product Name
5-FLUORO-2-HYDROXYMETHYL PYRIDINE
CAS No.
802325-29-7
Chemical Name
5-FLUORO-2-HYDROXYMETHYL PYRIDINE
Synonyms
EOS-60647;(5-Fluoropyridin-2-yl);5-fluoro-2-Pyridinemethanol;5-Fluoropyridine-2-methanol;5-Fluoro-2-hydroxymethyl ...;(5-fluoro-2-pyridyl)methanol;(5-fluoropyridin-2-y)methanol;2-Pyridinemethanol, 5-fluoro-;(5-fluoro-2-pyridinyl)methanol;5-FLUORO-2-HYDROXYMETHYL PYRIDINE
CBNumber
CB3816967
Molecular Formula
C6H6FNO
Formula Weight
127.12
MOL File
802325-29-7.mol
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5-FLUORO-2-HYDROXYMETHYL PYRIDINE Property

Boiling point:
200.4±25.0 °C(Predicted)
Density 
1.262±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
13.08±0.10(Predicted)
Appearance
Light yellow to brown Liquid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F597410
Product name
5-Fluoro-2-hydroxymethylpyridine
Packaging
250mg
Price
$50
Updated
2021/12/16
Matrix Scientific
Product number
068879
Product name
5-Fluoro-2-hydroxymethyl pyridine
Purity
>95%
Packaging
500mg
Price
$51
Updated
2021/12/16
Matrix Scientific
Product number
068879
Product name
5-Fluoro-2-hydroxymethyl pyridine
Purity
>95%
Packaging
1g
Price
$79
Updated
2021/12/16
AK Scientific
Product number
W8534
Product name
(5-Fluoropyridin-2-yl)methanol
Packaging
1g
Price
$128
Updated
2021/12/16
Apolloscientific
Product number
PC305009
Product name
5-Fluoro-2-(hydroxymethyl)pyridine
Packaging
1g
Price
$130
Updated
2021/12/16
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5-FLUORO-2-HYDROXYMETHYL PYRIDINE Chemical Properties,Usage,Production

Uses

5-Fluoro-2-hydroxymethylpyridine

Synthesis

148541-70-2

802325-29-7

General procedure for the synthesis of (5-fluoropyridin-2-yl)methanol from ethyl 5-fluoropyridine-2-carboxylate: to a solution of ethyl 5-fluoropyridine-2-carboxylate (377 mg, 2.23 mmol) in tetrahydrofuran (6 mL) was slowly added lithium aluminum hydride (LiAlH4, 73 mg, 3.34 mmol) at 0 °C. The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, it was quenched with ice water and the organic layer was subsequently extracted with ethyl acetate. The organic layer was dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography with ethyl acetate/hexane (20:80 to 60:40) as eluent to give (5-fluoropyridin-2-yl)methanol (309 mg, 54% yield, colorless oil).

References

[1] Patent: WO2008/8398, 2008, A2. Location in patent: Page/Page column 354
[2] Patent: EP1748048, 2007, A1. Location in patent: Page/Page column 35

5-FLUORO-2-HYDROXYMETHYL PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-FLUORO-2-HYDROXYMETHYL PYRIDINE Suppliers

Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
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64
Nan Jing Dirise Chemcial Co.,LTD
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025-52161033 15312098939
Fax
025-83254025
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sales@njdrschem.com
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China
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
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18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
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China
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8669
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ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
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China
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4999
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NovoChemy Ltd.
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021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
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Shanghai Topbiochem Technology Co., Ltd
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021-58170097
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info@topbiochem.com
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China
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Shanghai Jian Chao Chemical Technology Co., Ltd.
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150-2103-5486 18017383231
Fax
qq:2817624287
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983544897@qq.com
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China
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SuZhou ShiYa Biopharmaceuticals, Inc.
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86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
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China
ProdList
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9ding chemical ( Shanghai) Limited
Tel
4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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SynAsst Chemical.
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021-60343070
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021-35122006
Country
China
ProdList
12740
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View Lastest Price from 5-FLUORO-2-HYDROXYMETHYL PYRIDINE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
(5-Fluoropyridin-2-yl)methanol 802325-29-7
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-FLUORO-2-HYDROXYMETHYL PYRIDINE 802325-29-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-FLUORO-2-HYDROXYMETHYL PYRIDINE 802325-29-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09