5-FLUORO-2-HYDROXYMETHYL PYRIDINE
- Product Name
- 5-FLUORO-2-HYDROXYMETHYL PYRIDINE
- CAS No.
- 802325-29-7
- Chemical Name
- 5-FLUORO-2-HYDROXYMETHYL PYRIDINE
- Synonyms
- EOS-60647;(5-Fluoropyridin-2-yl);5-fluoro-2-Pyridinemethanol;5-Fluoropyridine-2-methanol;5-Fluoro-2-hydroxymethyl ...;(5-fluoro-2-pyridyl)methanol;(5-fluoropyridin-2-y)methanol;2-Pyridinemethanol, 5-fluoro-;(5-fluoro-2-pyridinyl)methanol;5-FLUORO-2-HYDROXYMETHYL PYRIDINE
- CBNumber
- CB3816967
- Molecular Formula
- C6H6FNO
- Formula Weight
- 127.12
- MOL File
- 802325-29-7.mol
5-FLUORO-2-HYDROXYMETHYL PYRIDINE Property
- Boiling point:
- 200.4±25.0 °C(Predicted)
- Density
- 1.262±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 13.08±0.10(Predicted)
- Appearance
- Light yellow to brown Liquid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F597410
- Product name
- 5-Fluoro-2-hydroxymethylpyridine
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 068879
- Product name
- 5-Fluoro-2-hydroxymethyl pyridine
- Purity
- >95%
- Packaging
- 500mg
- Price
- $51
- Updated
- 2021/12/16
- Product number
- 068879
- Product name
- 5-Fluoro-2-hydroxymethyl pyridine
- Purity
- >95%
- Packaging
- 1g
- Price
- $79
- Updated
- 2021/12/16
- Product number
- W8534
- Product name
- (5-Fluoropyridin-2-yl)methanol
- Packaging
- 1g
- Price
- $128
- Updated
- 2021/12/16
- Product number
- PC305009
- Product name
- 5-Fluoro-2-(hydroxymethyl)pyridine
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
5-FLUORO-2-HYDROXYMETHYL PYRIDINE Chemical Properties,Usage,Production
Uses
5-Fluoro-2-hydroxymethylpyridine
Synthesis
148541-70-2
802325-29-7
General procedure for the synthesis of (5-fluoropyridin-2-yl)methanol from ethyl 5-fluoropyridine-2-carboxylate: to a solution of ethyl 5-fluoropyridine-2-carboxylate (377 mg, 2.23 mmol) in tetrahydrofuran (6 mL) was slowly added lithium aluminum hydride (LiAlH4, 73 mg, 3.34 mmol) at 0 °C. The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, it was quenched with ice water and the organic layer was subsequently extracted with ethyl acetate. The organic layer was dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography with ethyl acetate/hexane (20:80 to 60:40) as eluent to give (5-fluoropyridin-2-yl)methanol (309 mg, 54% yield, colorless oil).
References
[1] Patent: WO2008/8398, 2008, A2. Location in patent: Page/Page column 354
[2] Patent: EP1748048, 2007, A1. Location in patent: Page/Page column 35
5-FLUORO-2-HYDROXYMETHYL PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
5-FLUORO-2-HYDROXYMETHYL PYRIDINE Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from 5-FLUORO-2-HYDROXYMETHYL PYRIDINE manufacturers
- Product
- (5-Fluoropyridin-2-yl)methanol 802325-29-7
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-17
- Product
- 5-FLUORO-2-HYDROXYMETHYL PYRIDINE 802325-29-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-FLUORO-2-HYDROXYMETHYL PYRIDINE 802325-29-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09