Caronic anhydride
- Product Name
- Caronic anhydride
- CAS No.
- 67911-21-1
- Chemical Name
- Caronic anhydride
- Synonyms
- 6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione;aronicanhydride;caronic anhydride;Calderon anhydride;Vanillin Impurity 4;Caronic Anhydride >WIDELY Caronic anhydride;Caronic anhydride(Cas number:67911-21-1);6,6-Dimethyl-3-oxabicyclo[3.1.]hexane-2,4-dione;6,6-Dimethyl-3-oxa-bicyclo[3.1.0]hexan-2,4-dione
- CBNumber
- CB3855588
- Molecular Formula
- C7H8O3
- Formula Weight
- 140.14
- MOL File
- 67911-21-1.mol
Caronic anhydride Property
- Melting point:
- 53-57℃
- Boiling point:
- 246°C
- Density
- 1.274
- Flash point:
- 113°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Methanol
- form
- Solid
- color
- White
- Sensitive
- Moisture Sensitive
- InChI
- InChI=1S/C7H8O3/c1-7(2)3-4(7)6(9)10-5(3)8/h3-4H,1-2H3
- InChIKey
- QKAHKEDLPBJLFD-UHFFFAOYSA-N
- SMILES
- C12C(C1(C)C)C(=O)OC2=O
- CAS DataBase Reference
- 67911-21-1(CAS DataBase Reference)
Safety
- HazardClass
- IRRITANT
- HS Code
- 2914199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C2596
- Product name
- Caronic Anhydride
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $102
- Updated
- 2025/07/31
- Product number
- C2596
- Product name
- Caronic Anhydride
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $368
- Updated
- 2025/07/31
- Product number
- C184263
- Product name
- Caronic Anhydride
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- C184263
- Product name
- Caronic Anhydride
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FC75910
- Product name
- Caronic Anhydride
- Packaging
- 10g
- Price
- $57.6
- Updated
- 2021/12/16
Caronic anhydride Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Uses
Caronic anhydride, also known as 6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione, is a pharmaceutical intermediate mainly used as a synthesis of Boceprevir, an oral protease inhibitor of hepatitis C. It is widely used in agricultural chemicals and other organic synthesis field.
Synthesis
Step 1: Ethyl dichlorochrysanthemate in ethyl acetate is ozonized at -5??C until conversion exceeds 99%. Work-up, saponification, acidification, extraction, and concentration yield 3,3-dimethyl-1,2-cyclopropanedicarboxylic acid.
Step 2: The diacid is heated with acetic anhydride and sodium acetate at 170??C to form the anhydride via dehydration. Work-up and recrystallization from toluene/petroleum ether give 6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione (Caronic anhydride).
Caronic anhydride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Caronic anhydride manufacturers
- Product
- 6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione 67911-21-1
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-07-18
- Product
- Caronic anhydride 67911-21-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-09
- Product
- Caronic anhydride 67911-21-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-18