2-[2-(2-methoxyethoxy)ethoxy]ethylamine

Product Name: 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
CAS No.: 74654-07-2
Chemical Name: 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
Synonyms: 2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine;MPEG3-NH2;NH3-PEG3-OME;m-PEG3-Amine;MeO-PEG3-NH2;Methyl-PEG3-amine;H2N-(CH2CH2O)3-Me;3,6,9-Trioxa-1-aminodecane;3,6,9-Trioxadecane-1-amine;2,5,8-trioxatridecane-10-aMine
CBNumber: CB3899124
Molecular Formula: C7H17NO3
Formula Weight: 163.21
MOL File: 74654-07-2.mol

More

Less

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Property

Boiling point:: 106℃ (11 Torr)
Density: 0.978±0.06 g/cm3(Predicted)
refractive index: 1.4395 (589.3 nm 20℃)
storage temp.: 2-8°C
solubility: Soluble in Water, DMSO, DCM, DMF
form: Oil
pka: 8.74±0.10(Predicted)
color: Colorless to light yellow
InChI: InChI=1S/C7H17NO3/c1-9-4-5-11-7-6-10-3-2-8/h2-8H2,1H3
InChIKey: OKUWOEKJQRUMBW-UHFFFAOYSA-N
SMILES: C(N)COCCOCCOC

More

Less

Safety

HS Code: 2922190090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 901158
Product name: 2-(2-(2-Methoxyethoxy)ethoxy) ethanamine
Purity: ≥95%
Packaging: 5G
Price: $332
Updated: 2025/07/31

TCI Chemical

Product number: M3686
Product name: m-PEG3-Amine
Purity: min. 95.0 %
Packaging: 200MG
Price: $90
Updated: 2025/07/31

TCI Chemical

Product number: M3686
Product name: m-PEG3-Amine
Purity: min. 95.0 %
Packaging: 1G
Price: $270
Updated: 2025/07/31

TRC

Product number: M220438
Product name: 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine
Packaging: 250mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M220438
Product name: 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine
Packaging: 2.5g
Price: $175
Updated: 2021/12/16

More

Less

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Chemical Properties,Usage,Production

Description

m-PEG3-amine is a PEG reagent containing an amino group (NH2). The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG3-amine whose chemical name 2-[2-(2-methoxyethoxy)ethoxy]ethylamine,it is a PROTAC bridge, belonging to the PEG class, which can be used to synthesize a series of PROTAC molecules, and can also be used for the synthesis of antibody drug conjugates (ADCs).

Synthesis

2-[2-(2-methoxyethoxy)ethoxy]ethylamine is an organic intermediate, which can be prepared from triethylene glycol monomethyl ether as raw material to prepare 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate, and then Reaction with sodium azide,and then Reacts with sodium azide to finally yield 3,6,9-trioxa-1-aminodecane.

IC 50

Cleavable Linker; PEGs

References

[1] Patent: WO2015/191433, 2015, A1. Location in patent: Paragraph 0041
[2] Chemische Berichte, 1980, vol. 113, # 5, p. 1691 - 1707
[3] Molecules, 2015, vol. 20, # 9, p. 16085 - 16102
[4] Chemistry - An Asian Journal, 2011, vol. 6, # 1, p. 149 - 156
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 48, p. 15461 - 15465

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Suppliers

China 153 Germany 1 India 2 United Kingdom 1 United States 13 Global 170

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 21193
Advantage: 58

9i LLC

Tel: +18039569191
Fax: +13026429191
Email: MWan@NiNeiLab.com
Country: United States
ProdList: 418
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

PurePEG，LLC

Tel: --
Fax: --
Email: info@purepeg.com
Country: United States
ProdList: 697
Advantage: 58

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Angene International Limited

Tel: --
Fax: --
Email: sales@angenechemical.com
Country: United States
ProdList: 100
Advantage: 50

More

Less

View Lastest Price from 2-[2-(2-methoxyethoxy)ethoxy]ethylamine manufacturers

LAURENT

Product: mPEG3-NH2 74654-07-2
Price: US $4560.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-20

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: m-PEG3-Amine 74654-07-2
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-06

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG3-amine 74654-07-2
Price: US $0.00/g
Min. Order: 25g
Purity: >98.00%
Supply Ability: 25g
Release date: 2024-03-27

74654-07-2, 2-[2-(2-methoxyethoxy)ethoxy]ethylamineRelated Search:

OCTAETHYLENE GLYCOL MONOMETHYL ETHER Methyl-PEG3-MS Methyl-PEG9-t-butyl ester 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Nonaethylene glycol HEXAETHYLENE GLYCOL MONOMETHYL ETHER BIOTIN-XX-NHS H2N-PEG24-tBu 2,5,8,11,14,17,20-Heptaoxadocosane-22-thiol Boc-1-amino-3,6-dioxa-8-octanediamine 2-(2-Methoxyethoxy)ethanamine alpha, oMega-Dipropionic acid triethylene glycol HS-PEG8-CH2CH2COOH 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane-28-thiol DODECAETHYLENE GLYCOL alpha-aMine-oMega-propionic acid octaethylene glycol N3-PEG6-tBu Amino-PEG2-acid

2-[2-(2-methoxyethoxy)ethoxy]ethylamine

2-[2-(2-Methoxyethoxy)ethoxy]ethanamine

3,6,9-Trioxadecane-1-amine

2,5,8-trioxatridecane-10-aMine

MPEG3-NH2

EthanaMine,2-[2-(2-Methoxyethoxy)ethoxy]-

3,6,9-Trioxa-1-aminodecane

Methyl-PEG3-amine

m-PEG3-Amine

NH3-PEG3-OME

2-(2-(2-Methoxyethoxy)ethoxy) ethanamine >=95%

MeO-PEG3-NH2

2-(2-(2-Methoxyethoxy)ethoxy)-eth

2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine

H2N-(CH2CH2O)3-Me

mPEG3-NH2/Ethanamine, 2-[2-(2-methoxyethoxy)ethoxy]-

74654-07-2

MeO-PEG-NH2

peg