ChemicalBook > CAS DataBase List > 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester

4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester

Product Name
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester
CAS No.
155405-80-4
Chemical Name
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester
Synonyms
X6;PMD;Pemedolac intermediate;Pemetrexed Impurity 13;PeMetrexed disodiuM INT-3;PeMetrexed Acid Methyl Ester;Pemetrexed Acid Methyl Ester Impurity;4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrroL;4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5...;Methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)
CBNumber
CB41012505
Molecular Formula
C16H16N4O3
Formula Weight
312.32
MOL File
155405-80-4.mol
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4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester Property

Melting point:
>220 °C
Density 
1.44
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Very Slightly, Heated)
form 
Solid
pka
11.21±0.20(Predicted)
color 
Off-White to Pale Beige
InChI
InChI=1S/C16H16N4O3/c1-23-15(22)10-5-2-9(3-6-10)4-7-11-8-18-13-12(11)14(21)20-16(17)19-13/h2-3,5-6,8H,4,7H2,1H3,(H4,17,18,19,20,21)
InChIKey
GDEKSBCRJKAARB-UHFFFAOYSA-N
SMILES
C(OC)(=O)C1=CC=C(CCC2C3C(=O)NC(N)=NC=3NC=2)C=C1
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Safety

HS Code 
2933.99.8290
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2426
Product name
Methyl 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$28
Updated
2023/01/07
TCI Chemical
Product number
M2426
Product name
Methyl 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$104
Updated
2024/03/01
TRC
Product number
A604950
Product name
4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoicAcidMethylEster
Packaging
100mg
Price
$145
Updated
2021/12/16
AK Scientific
Product number
W3385
Product name
Methyl 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate
Packaging
10g
Price
$192
Updated
2021/12/16
Matrix Scientific
Product number
090843
Product name
Methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo-[2,3-d]pyrimidin-5-yl)ethyl)benzoate
Purity
95+%
Packaging
250mg
Price
$243
Updated
2021/12/16
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4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Pink Solid

Uses

An intermediate in the preparation of Pemetrexed Disodium (P219500) and its derivatives as anticancer agents.

4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester Suppliers

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View Lastest Price from 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester manufacturers

Career Henan Chemical Co
Product
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester 155405-80-4
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-07-26

155405-80-4, 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl esterRelated Search:

Methyl 4-cyanobenzoate Ethanol Methyl 4-formylbenzoate Ethylparaben Ethyl formate Methyl 2-iodobenzoate Ethyl cyanoacetate Methyl benzoate Ethyl pyruvate Ethyl acetate ISOXADIFEN-ETHYL Methylparaben Ethyl acrylate Methyl 4-(4-hydroxybut-1-ynyl)benzoate Methyl 4-(4-oxobutyl)benzoate 4-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester 2,4-Diamino-6-hydroxypyrimidine N-[4-[3-(2,6-DiaMino-1,4-dihydro-4-oxo-5-pyriMidinyl)-3-oxopropyl]benzoyl]-L-glutaMic Acid

  • Methyl 4-[2-(2-Amino-4,7-dihydro-4-oxo-3<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-5-yl)ethyl]benzoate
  • Pemedolac intermediate
  • 2-Amino-4,7-dihydro-5-[2-[4-(methoxycarbonyl)phenyl]ethyl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine
  • PMD
  • Methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Methyl Ester
  • Benzoic acid,4-[2-(2-aMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]-,Methyl ester
  • 4-[2-(2-AMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoic Acid Methyl Ester
  • methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate
  • X6
  • Methyl 4-(2-(2-aMino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl)benzoate
  • Methyl 4-[2-(2-AMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoate
  • PeMetrexed Acid Methyl Ester
  • 4-[2-(2-AMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl] Ethyl benzoate
  • PeMetrexed disodiuM INT-3
  • 4-[2-(2-AMino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoic a
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid methyl ester
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-6-yl)ethyl] benzoic acid methyl ester
  • Pemetrexed Impurity 13
  • Methyl4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate&gt
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrroL
  • 4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-1H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)ETHYL]BENZOIC ACID METHYL ESTER CAS 155405-80-4
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5...
  • Methyl 4-[2-(2- amino -4,7- dihydro -4- oxo -1H- pyrrole [2,3-d] pyrimidine -5- yl) ethyl] benzoate
  • 4-(2-(2-amino-4,7-dihydro-4-oxo-3h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate
  • Methyl 4- [2- (2-amino-4,7-dihydro-4-ox-1H-pyrrole [2,3-d] pyrimidin-5-yl) ethyl] benzoate
  • Pemetrexed Acid Methyl Ester Impurity
  • Methyl 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate, ≥ 98.0%
  • 155405-80-4
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