ChemicalBook > CAS DataBase List > Cefozopran hydrochloride

Cefozopran hydrochloride

Product Name: Cefozopran hydrochloride
CAS No.: 113981-44-5
Chemical Name: Cefozopran hydrochloride
Synonyms: Czop;D02233;Firstcin (tn);Cefozopran hydrochlo;Cefozopran Impurity 1;SCE-2787 hydrochloride;Cefozopran hydrochloride;Cefozopran Hydrochloride RS;Cefozopran hydrochloride (jp15);Cefozopran hydrochloride USP/EP/BP
CBNumber: CB41074592
Molecular Formula: C19H18ClN9O5S2
Formula Weight: 551.98
MOL File: 113981-44-5.mol

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Cefozopran hydrochloride Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: Solid
color: White to light yellow
Water Solubility: Water : ≥ 52 mg/mL (94.20 mM)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-3504
Product name: Cefozopran(hydrochloride)
Packaging: 50mg
Price: $211
Updated: 2021/12/16

ChemScene

Product number: CS-3504
Product name: Cefozopran(hydrochloride)
Packaging: 100mg
Price: $319
Updated: 2021/12/16

Ambeed

Product number: A522832
Product name: Cefozopranhydrochloride
Purity: 98%
Packaging: 10mg
Price: $19
Updated: 2021/12/16

Ambeed

Product number: A522832
Product name: Cefozopranhydrochloride
Purity: 98%
Packaging: 50mg
Price: $33
Updated: 2021/12/16

Crysdot

Product number: CD31004489
Product name: Cefozopranhydrochloride
Purity: 98+%
Packaging: 100mg
Price: $253
Updated: 2021/12/16

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Cefozopran hydrochloride Chemical Properties,Usage,Production

Uses

Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms[1][2].

Antimicrobial activity

Cefazolam hydrochloride is suitable for Staphylococcus, Streptococcus, Enterococcus, Peptostreptococcus, Escherichia coli, Enterobacter, Serratia, Klebsiella, Citrobacter, Proteus, Pseudomonas, Influenza Bacillus, Acinetobacter, Bacteroidetes, septicemia caused by sensitive bacteria to cefazolam hydrochloride, trauma infection, respiratory system, urinary system and abdominal cavity, pelvic purulent inflammation, ophthalmology and ENT inflammation, etc.

Biological Activity

Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. As an antibiotic, it has broad-spectrum antibacterial activity and can inhibit most Gram-negative and Gram-positive bacteria.

in vitro

Cefozopran (SCE-2787) is a fourth-generation cephalosporin that has good activity against gram-positive organisms including methicillin-susceptible staphylococci, enterococci, and viridans group streptococci; and against gram-negative organisms including hemophilus influenza. Moreover, cefozopran has comparatively good activity against enterococci and P. aeruginosa , which are refractory to other cephalosporins.

in vivo

Cefozopran (SCE-2787) (5-80 mg/kg; sc; twice a day for 5 days; four-week-old ICR male mice) is effective against acute respiratory tract infections caused by Kiebsiella pneumonia DT-S. In the model of chronic respiratory tract infection caused by K. pneumoniae 27, Cefozopran (20-80 mg/kg; sc; twice a day for 7 days; five-week-old CBA/J female mice) is as effective as Ceftazidime.

IC 50

β-lactam

References

[1] Sato T, et al. A prospective, randomized study comparing cefozopran with piperacillin-tazobactam plus ceftazidime as empirical therapy for febrile neutropenia in children with hematological disorders. Pediatr Blood Cancer. 2008;51(6):774-777. DOI:10.1002/pbc.21692
[2] Iizawa Y, et al. Therapeutic effect of cefozopran (SCE-2787), a new parenteral cephalosporin, against experimental infections in mice. Antimicrob Agents Chemother. 1993;37(1):100-105. DOI:10.1128/AAC.37.1.100

Cefozopran hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cefozopran hydrochloride manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Cefozopran hydrochloride 113981-44-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 300 MT
Release date: 2020-05-23

Career Henan Chemical Co

Product: Cefozopran hydrochloride 113981-44-5
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,50kg
Release date: 2020-01-16

Cangzhou Wanyou New Material Technology Co.,Ltd

Product: Cefozopran hydrochloride 113981-44-5
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kgs
Release date: 2019-07-30

113981-44-5, Cefozopran hydrochlorideRelated Search:

5-Chlorovaleric acid Cetirizine dihydrochloride 2,1,3-Benzothiadiazole Acetaminophen Diphenhydramine Hydrochloride Glycine ALTRENOGEST Diphenolic acid 4-(Diethylamino)salicylaldehyde Acetamide Thioacetamide Topotecan hydrochloride 1-AdaMantanethylaMine Cefozopran DIACETAMIDE 2-Mercapto-5-methyl-1,3,4-thiadiazole Tris(hydroxymethyl)aminomethane DL-α-Tocopherol

Cefozopran hydrochloride

(6R,7R)-7-[[(2E)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin-4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride

Cefozopran hydrochloride (jp15)

Czop

D02233

Firstcin (tn)

Cefozopran hydrochlo

SCE-2787 hydrochloride

Cefozopran hydrochloride USP/EP/BP

1-(((6R,7R)-7-((Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)imidazo[1,2-b]pyridazin-1-ium chloride

Cefozopran Impurity 1

Cefozopran Hydrochloride RS

113981-44-5

C19H17N9O5S2HCl

Cefozopran Hydrochloride and its intermediates