ChemicalBook > CAS DataBase List > 6-Bromo-1-chloroisoquinoline
6-Bromo-1-chloroisoquinoline
- Product Name
- 6-Bromo-1-chloroisoquinoline
- CAS No.
- 205055-63-6
- Chemical Name
- 6-Bromo-1-chloroisoquinoline
- Synonyms
- SKL322;6-Bromo-1-chL;6-Bromo-2-chloroisoquinoline;1-Chloro-6-bromoisoquinoline;6-BROMO-1-CHLORO-ISOQUINOLINE;Isoquinoline, 6-bromo-1-chloro-;1-chloro -6-broMideisoquinoline;6-Bromo-1-chloroisoquinoline ISO 9001：2015 REACH;6-Bromo-1-chloroisoquinoline 1-Chloro-6-bromoisoquinoline
- CBNumber
- CB4109550
- Molecular Formula
- C9H5BrClN
- Formula Weight
- 242.5
- MOL File
- 205055-63-6.mol
More
Less
6-Bromo-1-chloroisoquinoline Property
- Boiling point:
- 349.5±22.0 °C(Predicted)
- Density
- 1.673
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 1.48±0.38(Predicted)
- form
- powder
- color
- Light yellow to yellow
- InChI
- InChI=1S/C9H5BrClN/c10-7-1-2-8-6(5-7)3-4-12-9(8)11/h1-5H
- InChIKey
- VOAHGGQULSSGQW-UHFFFAOYSA-N
- SMILES
- C1(Cl)C2=C(C=C(Br)C=C2)C=CN=1
More
Less
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- B682515
- Product name
- 6-Bromo-1-chloroisoquinoline
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
Apolloscientific
- Product number
- OR300053
- Product name
- 6-Bromo-1-chloroisoquinoline
- Packaging
- 1g
- Price
- $73
- Updated
- 2021/12/16
Frontier Specialty Chemicals
- Product number
- CAPOB11655
- Product name
- 6-Bromo-1-chloroisoquinoline
- Purity
- 95%
- Packaging
- 1g
- Price
- $88
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 070409
- Product name
- 6-Bromo-1-chloroisoquinoline
- Purity
- 97%
- Packaging
- 1g
- Price
- $89
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB42058
- Product name
- 6-Bromo-1-chloroisoquinoline
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
More
Less
6-Bromo-1-chloroisoquinoline Chemical Properties,Usage,Production
Chemical Properties
Yellow solid
Uses
6-Bromo-1-chloroisoquinoline has been used as a reactant in the preparation of phenylimidazoles as Smoothened antagonists.
Synthesis
N-oxide 6-bromoisoquinoline (1.82 g, 8.12 mmol) was dissolved in dry DCM (80 mL), POCl3 (1.12 ml, 1.5 eq) was added dropwise at RT. The reaction was heated to 45°C for 2 hours. After cooling down the reaction to RT, DCM and excessive POCl3 were removed under the vacuum. The crude was re-dissolved into 100mL DCM and was washed by saturated Na2CO3, water and brine. The separated organic layer was dried over Na2SO4, and concentrated to give brown solid. The crude was purified by flash column using 2% MeOH in DCM to get the pale yellow solid 6-Bromo-1-chloroisoquinoline.
References
[1] European Journal of Organic Chemistry, 2016, vol. 2016, # 8, p. 1606 - 1611
[2] Patent: WO2013/185353, 2013, A1. Location in patent: Page/Page column 27
[3] Patent: WO2014/165232, 2014, A1. Location in patent: Paragraph 0202; 0203
[4] Patent: US2015/119387, 2015, A1. Location in patent: Paragraph 0203; 0204
[5] Patent: JP2017/95498, 2017, A. Location in patent: Paragraph 0122; 0123
6-Bromo-1-chloroisoquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
6-Bromo-1-chloroisoquinoline Suppliers
- Tel
- 0592-6266840 15750707980
- sales@chemsdano.com
- Country
- China
- ProdList
- 357
- Advantage
- 57
- Tel
- 1365-13651960330 13651960330
- xiangfeixia@jspharmatech.com
- Country
- China
- ProdList
- 356
- Advantage
- 58
- Tel
- 13540909846 13882008651
- 3848291069@qq.com
- Country
- China
- ProdList
- 3001
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9309
- Advantage
- 66
- Tel
- +86-21-68182121
- Fax
- +86-21-68182121
- Country
- China
- ProdList
- 882
- Advantage
- 52
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 10-61256048 13810278579
- Fax
- +86 10 61256049
- sales@zeroschem.com
- Country
- China
- ProdList
- 1371
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- +86 (21) 6435-5022
- Country
- China
- ProdList
- 4267
- Advantage
- 65
- Tel
- 13761627472
- Fax
- 86-21-64965863
- 183009664@qq.com
- Country
- China
- ProdList
- 649
- Advantage
- 62
- Tel
- 021-20958197 20965099
- Fax
- 021-20960837
- sales@skychemical.com
- Country
- China
- ProdList
- 1183
- Advantage
- 57
- Tel
- 18030648795
- Fax
- 028-61777050
- sales@cdforestchem.com
- Country
- China
- ProdList
- 2000
- Advantage
- 58
- Tel
- +86-21-60341587
- Fax
- +86-21-61294319
- sales@topbiochem.com
- Country
- China
- ProdList
- 6175
- Advantage
- 58
- Tel
- 021-54849683 13601642561
- Fax
- +86-21-54375689
- sales@keepontech.com
- Country
- China
- ProdList
- 998
- Advantage
- 59
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 021-61552785
- Fax
- 021-55660885
- sales@shshiji.com
- Country
- China
- ProdList
- 9546
- Advantage
- 55
- Tel
- +86 (21) 6715-7650
- Fax
- +86 (21) 6715-7651
- sheepchem@163.com
- Country
- China
- ProdList
- 994
- Advantage
- 60
- Tel
- 18171398856 2968382473
- Fax
- 0086-21-50758330
- service@runpharm.com
- Country
- China
- ProdList
- 716
- Advantage
- 55
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- 021-54880687
- Fax
- 021-54880687
- Country
- China
- ProdList
- 511
- Advantage
- 55
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- 422131432@qq.com
- Country
- China
- ProdList
- 9979
- Advantage
- 55
- Tel
- +86 (21) 5471-7132
- Fax
- +86 (21) 5471-6993
- Country
- China
- ProdList
- 344
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- +86 13590492756
- Fax
- +86 (0)21 57626234
- michael.he@sensechemicals.com
- Country
- China
- ProdList
- 426
- Advantage
- 58
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9476
- Advantage
- 58
- Tel
- 400-8592883
- Fax
- 0731-82251112
- sales@huatengsci.com
- Country
- China
- ProdList
- 5872
- Advantage
- 58
- Tel
- 18957373295
- Fax
- -
- Country
- China
- ProdList
- 1580
- Advantage
- 58
- Tel
- 025-66028182 18626450290
- yftan@aikonchem.com
- Country
- China
- ProdList
- 16679
- Advantage
- 50
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 21-58226973 18917146209
- Fax
- +86-21-51685790
- Joseph@novapharmas.com
- Country
- China
- ProdList
- 476
- Advantage
- 55
- Tel
- 010-60400365-8001 15910885229
- Fax
- 010-60400361
- service@bellenchem.com
- Country
- China
- ProdList
- 4514
- Advantage
- 60
- Tel
- 13770809694
- Fax
- +86 25 56203983
- googlexu_0114@sina.com
- Country
- China
- ProdList
- 990
- Advantage
- 58
- Tel
- 028-85434334 18108076537
- Fax
- QQ：245797092
- market@gianthx.com
- Country
- China
- ProdList
- 4505
- Advantage
- 56
- Tel
- 13817485796
- Fax
- QQ:895624079
- tim@wisacheampharm.com
- Country
- China
- ProdList
- 3593
- Advantage
- 58
- Tel
- 021-64340559 13651849907;
- Fax
- 021- 64345308
- xinyu_shi@jwypharmlab.com.cn
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- Fax
- -
- eric_feng1954@126.com
- Country
- China
- ProdList
- 9248
- Advantage
- 55
- Tel
- 021-34979681; 17701870669
- Fax
- 021-34979681
- 41513101@qq.com
- Country
- China
- ProdList
- 1785
- Advantage
- 55
- Tel
- 021-58088081 Q2635253576
- Fax
- QQ3382968513
- hailey@shsendpharm.com
- Country
- China
- ProdList
- 1984
- Advantage
- 55
- Tel
- 13812573443
- Fax
- -
- tongbenwan22@163.com
- Country
- China
- ProdList
- 1980
- Advantage
- 55
- Tel
- 021-20960837,QQ1332204249
- Fax
- 021-20960837
- sales@skychemical.com
- Country
- China
- ProdList
- 3341
- Advantage
- 55
- Tel
- 0371-86658258
- Fax
- 0371-60996044
- info@coreychem.com
- Country
- China
- ProdList
- 10453
- Advantage
- 58
- Tel
- 021-31761238 13167072949
- Fax
- 021-31761238
- 3146446224@qq.com
- Country
- China
- ProdList
- 1379
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 021-20242659 18930833303
- Fax
- +86 (21) 2024-2659
- Sales@changyanchem.cn
- Country
- China
- ProdList
- 5001
- Advantage
- 55
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
More
Less
View Lastest Price from 6-Bromo-1-chloroisoquinoline manufacturers
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 6-Bromo-1-chloroisoquinoline 205055-63-6
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-24
Hebei Yanxi Chemical Co., Ltd.
- Product
- 6-Bromo-1-chloroisoquinoline 205055-63-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-11-27
Career Henan Chemical Co
- Product
- 6-Bromo-1-chloroisoquinoline 205055-63-6
- Price
- US $8.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10tons
- Release date
- 2018-12-25
205055-63-6, 6-Bromo-1-chloroisoquinolineRelated Search:
1-chloroisoquinoline-4-carboxylic acid
1-chloro-5-fluoroisoquinoline
1-chloro-7-methoxyisoquinoline
8-Bromo-1-chloroisoquinoline
8-Bromoisoquinoline
Chlorobromoisocyanurate
5-Bromoisoquinoline
BCDMH
Isoquinoline
4-Bromoisoquinoline
7-Bromoisoquinoline
6-Bromoisoquinoline
1-Chloroisoquinoline
Difluorochloromethane
Bromine
Bromochloromethane
6-Bromo-1,3-dichloroisoquinoline
6-Bromo-1-chloroisoquinoline