TRI-P-TOLYLPHOSPHINE

Product Name: TRI-P-TOLYLPHOSPHINE
CAS No.: 1038-95-5
Chemical Name: TRI-P-TOLYLPHOSPHINE
Synonyms: TRIS(P-TOLYL)PHOSPHINE;TRIS(4-TOLYL)PHOSPHINE;tris(4-Methylphenyl)phosphane;Tri(p-toL;AURORA KA-1142;Tri-p-tolyphosphine;TRI-4-TOLYLPHOSPHINE;TRI-P-TOLYLPHOSPHINE;TRI-P-TOYL PHOSPHINE;tris-p-tolylphosphane
CBNumber: CB4117584
Molecular Formula: C21H21P
Formula Weight: 304.37
MOL File: 1038-95-5.mol

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TRI-P-TOLYLPHOSPHINE Property

Melting point:: 144-148 °C(lit.)
Boiling point:: 399.8±41.0 °C(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: Crystals or Crystalline Powder
color: White to light yellow
Water Solubility: Insoluble in water.
Sensitive: Air Sensitive
BRN: 651045
InChI: InChI=1S/C21H21P/c1-16-4-10-19(11-5-16)22(20-12-6-17(2)7-13-20)21-14-8-18(3)9-15-21/h4-15H,1-3H3
InChIKey: WXAZIUYTQHYBFW-UHFFFAOYSA-N
SMILES: P(C1=CC=C(C)C=C1)(C1=CC=C(C)C=C1)C1=CC=C(C)C=C1
CAS DataBase Reference: 1038-95-5(CAS DataBase Reference)
EPA Substance Registry System: Phosphine, tris(4-methylphenyl)- (1038-95-5)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: SZ3880000
F: 10-23
TSCA: TSCA listed
HS Code: 29319090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 287830
Product name: Tri(p-tolyl)phosphine
Purity: 98%
Packaging: 5g
Price: $59.62
Updated: 2025/07/31

TCI Chemical

Product number: T0862
Product name: Tri(p-tolyl)phosphine
Purity: >96.0%(GC)
Packaging: 5g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: T0862
Product name: Tri(p-tolyl)phosphine
Purity: >96.0%(GC)
Packaging: 25g
Price: $98
Updated: 2025/07/31

Strem Chemicals

Product number: 15-8120
Product name: Tri-p-tolylphosphine, 98%
Packaging: 5g
Price: $60
Updated: 2024/03/01

Strem Chemicals

Product number: 15-8120
Product name: Tri-p-tolylphosphine, 98%
Packaging: 25g
Price: $235
Updated: 2024/03/01

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TRI-P-TOLYLPHOSPHINE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

suzuki reaction

Uses

Tri(p-tolyl)phosphine is used as pharmaceutical intermediate.

Application

Tri-p-tolylphosphine is commonly used in pharmaceutical manufacturing as a ligand in catalysis, particularly in palladium-catalyzed cross-coupling reactions. These reactions are crucial for forming carbon-carbon bonds in drug synthesis.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings

Synthesis

20 g Sodium (0.870 mol) was added to 125 ml toluene, then the mixture was heated up to 383 K and stirred to form fine particles of sodium, which subsequently melted. Then the temperature was lowered to 323 K. P-chlorotoluene (55.2 g /0.436 mol) and phosphorus trichloride (19.8 g / 0.144 mol) were added, keeping the temperature between 323 K and 333 K for two hours. The product was concentrated in a vacuum to gain a white solid (35.0 g, 80%) (Brown et al., 1988). The pure title compound (TRI-P-TOLYLPHOSPHINE) was obtained by crystallizing from methanol.[1]

References

[1] Tri-p-tolylphosphine. Crystallographic Communications. August 2008 64(Pt 9):o1783-o1783

TRI-P-TOLYLPHOSPHINE Preparation Products And Raw materials

Raw materials

Ethanol 5-Bromo-m-xylene Phosphorus trichloride 4-Bromotoluene Tetrahydrofuran Ethyl acetate Hydrochloric acid Dichloromethane PETROLEUM ETHER Magnesium

Preparation Products

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TRI-P-TOLYLPHOSPHINE Suppliers

Austria 1 Belgium 3 China 290 Germany 6 India 22 Japan 6 Norway 1 Russia 1 Slovakia 1 Switzerland 3 United Kingdom 11 United States 42 Global 387

Xinxiang Runyu Material Co., Ltd.

Tel: 166-166-37336996 15690792173
Fax: 0373-7759608
Email: chenxi.song@runvmat.com
Country: China
ProdList: 285
Advantage: 55

Puyang Huicheng Electronic Material Co. Ltd.

Tel: 0393-8910800 18339358320
Fax: 0393-8912775
Email: info@huichengchem.com
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BeiJing Greenchem Technology Co.,Ltd.

Tel: 131-21959385 18804271668
Fax: 010-62925455
Email: chemrocking@bjgreenchem.com
Country: China
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Jiangxi Sunway Chemical Co., Ltd.

Tel: 15888611133; 13566409786;18605760166
Email: trade@jxswchem.com
Country: China
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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

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Fax: 86-21-61259102
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Beijing Donghualituo Techonlogy Development Co.,Ltd.

Tel: 010-88425576
Fax: (+86)-10-88425546
Email: sales@dhltchem.com
Country: China
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INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
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Country: China
ProdList: 1995
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

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View Lastest Price from TRI-P-TOLYLPHOSPHINE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Tri-p-tolylphosphine 1038-95-5
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Shanghai UCHEM Inc.

Product: Tri-p-tolylphosphine 1038-95-5
Price: US $7.00-62.00/g
Min. Order: 5g
Purity: 0.98
Supply Ability: 100kg
Release date: 2023-12-07

Shaanxi Dideu Medichem Co. Ltd

Product: Tri-p-tolylphosphine 1038-95-5
Price: US $1.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-01-14

1038-95-5, TRI-P-TOLYLPHOSPHINERelated Search:

Tributyl(2-phenylethenyl)stannane DICHLOROTRIS(TRIPHENYLPHOSPHINE)RUTHENIUM(II) METHYLTRIBUTYLPHOSPHONIUM IODIDE Tributylphosphine TRI-N-BUTYLPHOSPHINE OXIDE TRIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]PHOSPHINE Triphenylphosphine TRIS(PENTAFLUOROPHENYL)BORANE TRIS(PENTAFLUOROPHENYL)PHOSPHINE Tris(nonylphenyl) phosphite TRIS(2-METHOXYPHENYL)PHOSPHINE PHOSPHOROUS ACID TRIS(4-METHYLPHENYL) ESTER TRIMESITYLPHOSPHINE TRI-P-TOLYLPHOSPHINE TRIS[4-(PERFLUOROOCTYL)PHENYL]PHOSPHINE TRIS(4-TRIFLUOROMETHYLPHENYL)PHOSPHINE Dibromobis(tri-o-tolylphosphine)palladium(II), Pd 12% Tri(o-tolyl)phosphine

Three pairs of benzyl phosphonic

Tri(<i>p</i>-tolyl)phosphine

Tri(p-tolyl)phosphine 98%

LABOTEST-BB LTBB005429

AURORA KA-1142

TRI-4-TOLYLPHOSPHINE

TRIS(P-TOLYL)PHOSPHINE

TRI-P-TOLYLPHOSPHINE

TRIS(4-METHYLPHENYL)PHOSPHINE

TRIS(4-TOLYL)PHOSPHINE

PHOSPHORUS TRI-P-TOLYL

Phosphine, tri-p-tolyl-

Phosphine, tris(p-tolyl)-

tri-(4-Methylphenyl)phosphine

Tri-para-tolylphosphine

tris(4-methylphenyl)-phosphin

Tris(p-methylphenyl)phosphine

tris(p-tolyl)-phosphin

Tri(p-toL

Tri-p-tolyphosphine

Tris(p-tolyl)phosphine, 98+%

Tri-p-tolylphosphine,98%

TRI-P-TOYL PHOSPHINE

TRIS(P-TOLYL)PHOSPHINE (TPTP)

Tri-p-tolylphosphine,95%

tris(4-Methylphenyl)phosphane

Phosphine,tris(4-Methylphenyl)-

Tri(p-tolyl)phosphine &gt

Tri-p-tolylphosphine, 98%, for synthesis

tris-p-tolylphosphane

Three phenylmethylphosphine

Tris(p-toluene)phosphine

1038-95-5

1038-95-7

1038-95-6

pCH3C6H43P

Catalysis and Inorganic Chemistry

Phosphine Ligands

Phosphorus Compounds

Basic Phosphine LigandsCatalysis and Inorganic Chemistry

Catalysis and Inorganic Chemistry

Cross-Coupling

Phosphine Ligands

Phosphorus Compounds

Phosphine Ligands

Synthetic Organic Chemistry

organophosphorus ligand

Achiral Phosphine

Aryl Phosphine