N-[4-(-Carboxycyclohexylmethyl)]maleimide

Product Name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
CAS No.: 64987-82-2
Chemical Name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
Synonyms: Mal-Cyclohexanecarboxylicacid;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl);4-(N-MaleiMidoMethyl)cyclohexanecarboxylic acid;4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 95%;4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid;4-(Maleimidomethyl)cyclohexanecarboxylic Acid (Discontinued, see C177860);4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]Cyclohexanecarboxylic acid;Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-;4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid
CBNumber: CB41176520
Molecular Formula: C12H15NO4
Formula Weight: 237.25
MOL File: 64987-82-2.mol

More

Less

N-[4-(-Carboxycyclohexylmethyl)]maleimide Property

Melting point:: 157-158°C
Boiling point:: 433.6±18.0 °C(Predicted)
Density: 1.329±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Chloroform, Methanol
form: Solid
pka: 4.80±0.10(Predicted)
color: Pale Yellow
InChI: InChI=1S/C12H15NO4/c14-10-5-6-11(15)13(10)7-8-1-3-9(4-2-8)12(16)17/h5-6,8-9H,1-4,7H2,(H,16,17)
InChIKey: LQILVUYCDHSGEU-UHFFFAOYSA-N
SMILES: C1(C(O)=O)CCC(CN2C(=O)C=CC2=O)CC1

More

Less

Safety

HS Code: 2925.19.9100

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: M3218
Product name: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
Packaging: 1G
Price: $234
Updated: 2024/03/01

TCI Chemical

Product number: M3218
Product name: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
Packaging: 5G
Price: $819
Updated: 2024/03/01

TRC

Product number: C177860
Product name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
Packaging: 25mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC19767
Product name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
Packaging: 5G
Price: $150
Updated: 2021/12/16

AK Scientific

Product number: J95578
Product name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
Packaging: 250mg
Price: $160
Updated: 2021/12/16

More

Less

N-[4-(-Carboxycyclohexylmethyl)]maleimide Chemical Properties,Usage,Production

Description

4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Chemical Properties

White Solid

Uses

A sulfhydryl crosslinking reagent.

Uses

An amino reactive reagent.

Definition

N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.

N-[4-(-Carboxycyclohexylmethyl)]maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-[4-(-Carboxycyclohexylmethyl)]maleimide Suppliers

Americas 1 Canada 2 China 68 Europe 1 India 3 Japan 1 United Kingdom 3 United States 8 Global 87

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52925
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Medical Isotopes

Tel: --
Fax: --
Email: stohler@medicalisotopes.com
Country: United States
ProdList: 6181
Advantage: 68

NE Scientific

Tel: --
Fax: --
Country: United States
ProdList: 5030
Advantage: 55

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

BroadPharm. Inc.

Tel: --
Fax: --
Email: sales@broadpharm.com
Country: United States
ProdList: 891
Advantage: 50

More

Less

View Lastest Price from N-[4-(-Carboxycyclohexylmethyl)]maleimide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-Cyclohexanecarboxylicacid 64987-82-2
Price: US $0.00/g
Min. Order: 25g
Purity: >95.00%
Supply Ability: 25g
Release date: 2024-03-27

64987-82-2, N-[4-(-Carboxycyclohexylmethyl)]maleimideRelated Search:

Maleimido-Tri(Ethylene Glycol)-Propionic Acid Mal-PEG2-COOH Mal-PEG4-Acid Mal-PEG2-NHS ester Bis-Mal-Lysine-PEG4-TFP ester Maleimide-PEG4-NHS Ester Maleimide-PEG2-NHS Ester 3-Maleimidopropionic acid Mal-PEG2-acid Mal-Amido-PEG4-acid 2-MALEIMIDOETHYLAMINE HCL 4-MALEIMIDOBUTYRIC ACID 1h-pyrrole-2,5-dione, 1-[2-(2-aminoethoxy)ethyl]-, 2,2,2-trifluoroacetate (1:1) Maleimide-SS-amine Deruxtecan SMCC crosslinker SULFO-SMCC N-[4-(-Carboxycyclohexylmethyl)]maleimide

4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]Cyclohexanecarboxylic acid

4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 95%

4-(N-MaleiMidoMethyl)cyclohexanecarboxylic acid

4-(Maleimidomethyl)cyclohexanecarboxylic Acid (Discontinued, see C177860)

4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid

4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid

4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)

4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid

Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-

Mal-Cyclohexanecarboxylicacid

64987-82-2

Cross Linking Reagents

Maleimide Derivatives

MTS & Sulfhydryl Active Reagents

satralizumab-linker