Loperamide

Product Name: Loperamide
CAS No.: 106900-12-3
Chemical Name: Loperamide
Synonyms: R 58425;loperamide oxide;LoperaMide-d6 N-Oxide;Loperamide EP Impurity F;trans-Loperamide N-Oxide;Loperamide impurity-F(EP);Loperamide EP Impurity F HCl;Loperamide oxide monohydrate CRS;Loperamide USP Related Compound F;Loperamide Hydrochloride Impurity F
CBNumber: CB41179066
Molecular Formula: C29H33ClN2O3
Formula Weight: 493.04
MOL File: 106900-12-3.mol

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Loperamide Property

solubility: Practically insoluble in water, freely soluble in alcohol and in methylene chloride.
pka: 12.94±0.20(Predicted)
Stability:: Hygroscopic

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Safety

RIDADR: UN 2811 6.1 / PGIII
RTECS: TM4960200
HS Code: 2933399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000341
Product name: Loperamide oxide monohydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000341
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR2916
Product name: Loperamide Related Compound F
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 50MG
Price: $575
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP636
Product name: Loperamide N-oxide
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 25MG
Price: $273
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1370065
Product name: Loperamide oxide monohydrate
Packaging: 25mg
Price: $1490
Updated: 2024/03/01

TRC

Product number: L469460
Product name: trans-LoperamideN-Oxide
Packaging: 250mg
Price: $1040
Updated: 2021/12/16

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Loperamide Chemical Properties,Usage,Production

Chemical Properties

White or almost white powder, slightly hygroscopic.

Uses

Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.

Uses

Labelled Loperamide oxide (LOPOX). It is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.

Definition

ChEBI: Loperamide oxide is a diarylmethane.

Loperamide Preparation Products And Raw materials

Raw materials

Preparation Products

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Loperamide Suppliers

Canada 1 China 39 India 4 United Kingdom 1 United States 9 Global 54

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32079
Advantage: 58

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14332
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10404
Advantage: 58

Alfa Chemistry

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Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

NE Scientific

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Country: United States
ProdList: 5030
Advantage: 55

Riedel-de Haen AG

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Country: United States
ProdList: 6773
Advantage: 87

International Laboratory Limited

Tel: --
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Email: admin@intlab.org
Country: United States
ProdList: 5356
Advantage: 50

106900-12-3, LoperamideRelated Search:

1-(4-CHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL (R)-1-(4-CHLOROPHENYL)-1-PROPANOL fenpipramide 4-(4-CHLOROPHENYL)PIPERIDINE Alverine Trimethylamine N-oxide 4-(4-Chlorophenyl)piperidin-4-ol (Diphenyl-3,3 propyl)-1 phenyl-4 piperidine chlorhydrate [French] Loperamide Trimethylamine N-oxide dihydrate 2,2-DIPHENYLPROPYLAMINE HYDROCHLORIDE TRIETHYLAMINE N-OXIDE DIPHENAMID DESMETHYL LOPERAMIDE Loperamide

loperamide oxide

R 58425

trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide 1-oxide

trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-oxide monohydrate

Loperamide EP Impurity F

4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide N-oxide

LoperaMide-d6 N-Oxide

Loperamide impurity-F(EP)

trans-Loperamide N-Oxide

Loperamide Impurity 6（Loperamide EP Impurity F）

Loperamide oxide monohydrate CRS

1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-, 1-oxide, trans-

Loperamide EP Impurity F/ Loperamide Related Compound F (Loperamide N-Oxide)

4-[TRANS-4-(4-CHLOROPHENYL)-4-HYDROXY-1- OXIDOPIPERIDIN-1-YL]-N,N-DIMETHYL-2,2- DIPHENYLBUTANAMIDE HYDROCHLORIDE

Loperamide N-oxideQ: What is Loperamide N-oxide Q: What is the CAS Number of Loperamide N-oxide Q: What is the storage condition of Loperamide N-oxide Q: What are the applications of Loperamide N-oxide

Loperamide Related Compound F ((1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo-3,3-diphenylbu (1370065)

Loperamide Hydrochloride Impurity F

Loperamide EP Impurity F HCl

Loperamide USP Related Compound F

Loperamide Hydrochloride EP Impurity F

Loperamide EP Impurity F (Loperamide USP Related Compound F, trans-Loperamide N-Oxide)

106900-12-3

C29H27D6ClN2O3

Amines

Drug Analogues

Heterocycles

Intermediates & Fine Chemicals

Isotope Labelled Compounds

Metabolites & Impurities

Pharmaceuticals