Obtusifolin

Product Name: Obtusifolin
CAS No.: 477-85-0
Chemical Name: Obtusifolin
Synonyms: 10-dibromo-;Obtusifolin;Obtusifolin-RM;10-Dibromodecane;Obtusifolin, 10 mM in DMSO;Obtusifolin (anthraquinone);Obtusifolin ISO 9001：2015 REACH;2,8-Dihydroxy-1-Methoxy-3-Methylanthraquinone;Anthraquinone, 2,8-dihydroxy-1-methoxy-3-methyl-;2,8-dihydroxy-1-methoxy-3-methylanthracene-9,10-dione
CBNumber: CB41179369
Molecular Formula: C16H12O5
Formula Weight: 284.26
MOL File: 477-85-0.mol

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Obtusifolin Property

Melting point:: 242-243℃
Boiling point:: 528.0±50.0 °C(Predicted)
Density: 1.448±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: 2-8°C
solubility: DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.12 mg/ml
form: A solid
pka: 6.60±0.20(Predicted)
color: Yellow to orange

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL83880
Product name: Obtusifolin
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $453
Updated: 2025/07/31

Usbiological

Product number: 300707
Product name: Obtusifolin
Packaging: 10mg
Price: $490
Updated: 2021/12/16

ApexBio Technology

Product number: N2213
Product name: Obtusifolin
Packaging: 20mg
Price: $450
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259406
Product name: Obtusifolin
Purity: 99%
Packaging: 10mg
Price: $499.8
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259406
Product name: Obtusifolin
Purity: 99%
Packaging: 20mg
Price: $571.2
Updated: 2021/12/16

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Obtusifolin Chemical Properties,Usage,Production

Chemical Properties

Orange-yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Cassia seed.

Uses

Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway[1]. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein[2].

Definition

ChEBI: Obtusifolin is a dihydroxyanthraquinone.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

IC 50

NF-κB

References

[1] Choi BS, et al. Obtusifolin isolated from the seeds of Cassia obtusifolia regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via affecting NF-κB pathway. Phytother Res. 2019 Apr;33(4):919-928. DOI:10.1002/ptr.6284
[2] Hsu YL, et al. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein. J Agric Food Chem. 2014 Dec 10;62(49):11933-40. DOI:10.1021/jf5042905

Obtusifolin Preparation Products And Raw materials

Raw materials

Preparation Products

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Obtusifolin Suppliers

China 149 United States 10 Global 159

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Cheng Du Pufeide Biotechnology Co., Ltd.

Tel: 028-82610909 13388174823
Fax: 8171-1798
Email: scglp@glp-china.com
Country: China
ProdList: 1064
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

ALB Technology Limited

Tel: 702-983-3769
Fax: 702-983-3769
Email: sales@albtechnology.com
Country: United States
ProdList: 2993
Advantage: 55

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
Advantage: 55

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View Lastest Price from Obtusifolin manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Obtusifolin 477-85-0
Price: US $25.00/ASSAYS
Min. Order: 100ASSAYS
Purity: 99.5%
Supply Ability: 100 mt
Release date: 2024-11-19

Shaanxi Dideu Medichem Co. Ltd

Product: Obtusifolin 477-85-0
Price: US $1.00-22.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100000KG
Release date: 2024-08-06

Shanghai Standard Technology Co., Ltd.

Product: Obtusifolin 477-85-0
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-13

477-85-0, ObtusifolinRelated Search:

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9,10-Anthracenedione, 2,8-dihydroxy-1-methoxy-3-methyl-

Anthraquinone, 2,8-dihydroxy-1-methoxy-3-methyl-

Obtusifolin (anthraquinone)

Obtusifolin

2,8-Dihydroxy-1-Methoxy-3-Methylanthraquinone

2,8-dihydroxy-1-methoxy-3-methylanthracene-9,10-dione

Obtusifolin ISO 9001：2015 REACH

10-dibromo-

10-Dibromodecane

Obtusifolin-RM

Obtusifolin, 10 mM in DMSO

477-85-0

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract