4-AMINO-3,5-DIIODOPYRIDINE
- Product Name
- 4-AMINO-3,5-DIIODOPYRIDINE
- CAS No.
- 98136-86-8
- Chemical Name
- 4-AMINO-3,5-DIIODOPYRIDINE
- Synonyms
- 3,5-Diiodopyridin-4-amine;4-AMINO-3,5-DIIODOPYRIDINE;3,4-diiodo-4-aminopyridine;3,5-diiodo-4-aminopyridine;4-Pyridinamine, 3,5-diiodo-;Pyridine,4-aMino-3,5-diiodo-;4-AMINO-3,5-DIIODOPYRIDINE ISO 9001：2015 REACH
- CBNumber
- CB4129112
- Molecular Formula
- C5H4I2N2
- Formula Weight
- 345.91
- MOL File
- 98136-86-8.mol
4-AMINO-3,5-DIIODOPYRIDINE Property
- Melting point:
- 135-136℃
- Boiling point:
- 408.1±45.0 °C(Predicted)
- Density
- 2.679
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 5.42±0.24(Predicted)
- form
- solid
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- VBP00076
- Product name
- 3,5-Diiodopyridin-4-amine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $179
- Updated
- 2025/07/31
- Product number
- A632038
- Product name
- 4-Amino-3,5-diiodopyridine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- A632038
- Product name
- 4-Amino-3,5-diiodopyridine
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 187991
- Product name
- 3,5-Diiodopyridin-4-amine
- Packaging
- 1g
- Price
- $136
- Updated
- 2021/12/16
- Product number
- OR9959
- Product name
- 4-Amino-3,5-diiodopyridine
- Packaging
- 5g
- Price
- $169
- Updated
- 2021/12/16
4-AMINO-3,5-DIIODOPYRIDINE Chemical Properties,Usage,Production
Synthesis
504-24-5
98136-86-8
General procedure for the synthesis of 3,5-diiodo-4-aminopyridine from 4-aminopyridine: 500 mL of methanol, 3000 mL of water, 94.11 g (1.0 mol) of 4-aminopyridine, 224.10 g (1.35 mol) of potassium iodide, and 149.80 g (0.70 mol) of potassium iodate were added sequentially to the reaction flask. 160 mL of hydrochloric acid was slowly added dropwise with controlled titration rate, and the titration process lasted for 3 hours. After the dropwise addition, the reaction was continued for 1 hour. Subsequently, 50 mL of an aqueous solution containing 17.73 g (0.20 mol) of sodium chlorite was added dropwise. After the dropwise addition was completed, the reaction process was monitored by HPLC and the reaction was continued for 0.5 hours. Upon completion of the reaction, the reaction solution was diluted with 4000 mL of water, and then 6000 mg of trichloromethane was added in three portions as an extractant. The organic phase was washed sequentially with an aqueous solution containing sodium thiosulfate and an aqueous solution of sodium bicarbonate, separated and dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product of 3,5-diiodo-4-aminopyridine in gray color. The crude product was recrystallized with a mixed solvent of ethanol and water to give 318.23 g of white crystalline solid in 92.0% yield.
References
[1] Patent: CN104262242, 2016, B. Location in patent: Paragraph 0030; 0031
[2] Tetrahedron Letters, 2007, vol. 48, # 11, p. 1983 - 1986
4-AMINO-3,5-DIIODOPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-AMINO-3,5-DIIODOPYRIDINE Suppliers
- Tel
- +49 5662 408730
- Fax
- +49 5662 4087320
- info@synchem.de
- Country
- Germany
- ProdList
- 4705
- Advantage
- 70
View Lastest Price from 4-AMINO-3,5-DIIODOPYRIDINE manufacturers
- Product
- 4-AMINO-3,5-DIIODOPYRIDINE 98136-86-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-01
- Product
- 4-AMINO-3,5-DIIODOPYRIDINE 98136-86-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25