ChemicalBook > CAS DataBase List > 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI)

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI)

Product Name
1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI)
CAS No.
147081-59-2
Chemical Name
1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI)
Synonyms
-tert-Butyl 3-(methylamino);1-N-Boc-(S)-(methylamino)-pyrrolidine;1-N-Boc-3-(S)-(Methylamino) pyrrolidine;ert-butyl(3S)-3-(methylamino)pyrrolidine-1-carboxylate;tert-butyl (S)-3-(methylamino)pyrrolidine-1-carboxylate;tert-Butyl-(3S)-3-(methylamino)pyrrolidine-1-carboxylate;(3S)-(Methylamino)pyrrolidine-1-carboxylic acid tert-butyl ester;1,1-Dimethylethyl (3S)-3-(methylamino)-1-pyrrolidinecarboxylate.;(3S)-3-(Methylamino)-1-pyrrolidinecarboxylic acid tert-butyl ester;(3S)-3-(Methylamino)-1-Pyrrolidinecarboxylicacid 1,1-imethylethyl ester
CBNumber
CB41297481
Molecular Formula
C10H20N2O2
Formula Weight
200.28
MOL File
147081-59-2.mol
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1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI) Property

Boiling point:
269℃
Density 
1.03
Flash point:
117℃
storage temp. 
2-8°C(protect from light)
pka
10.02±0.20(Predicted)
Appearance
Colorless to light yellow Liquid
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B810408
Product name
(S)-tert-Butyl3-(methylamino)pyrrolidine-1-carboxylate
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
B810408
Product name
(S)-tert-Butyl3-(methylamino)pyrrolidine-1-carboxylate
Packaging
500mg
Price
$110
Updated
2021/12/16
TRC
Product number
B810408
Product name
(S)-tert-Butyl3-(methylamino)pyrrolidine-1-carboxylate
Packaging
1g
Price
$175
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB142634
Product name
(S)-tert-Butyl 3-(methylamino)pyrrolidine-1-carboxylate
Packaging
250mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
122573
Product name
(S)-1-Boc-3-(methylamino)pyrrolidine
Purity
97.0%
Packaging
1g
Price
$78
Updated
2021/12/16
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1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI) Chemical Properties,Usage,Production

Synthesis

892390-43-1

147081-59-2

To a stirred solution of (3S)-3-(formylamino)pyrrolidine-1-carboxylic acid tert-butyl ester (2.29 g, 10 mmol) in tetrahydrofuran (35 ml) at 0°C was slowly added a tetrahydrofuran solution of 1 M borane (32 ml, 32 mmol). The reaction mixture was stirred at room temperature for 18 h. The reaction was quenched with methanol (10 ml) followed by vacuum concentration. The resulting white solid was redissolved in methanol (30 ml) and heated to reflux for 18 hours. Finally, the solvent was removed by vacuum evaporation to afford (S)-1-Boc-3-(methylamino)pyrrolidine as a light yellow oil (2.45 g, 12.2 mmol, 100% yield). The product was characterized by 1HNMR (400 MHz, CDCl3): δ 1.45 (s, 9H), 1.47-1.77 (m, 2H), 1.71 (m, 1H), 2.03 (m, 1H), 2.43 (s, 3H), 3.04-3.26 (m, 1H), 3.29-3.58 (m, 2H); LRMS m/z ELSD- apci+ 201 [mh]+.

References

[1] Patent: WO2006/64336, 2006, A2. Location in patent: Page/Page column 43-44

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI) manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI) 147081-59-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26

147081-59-2, 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI)Related Search:

(S)-tert-butyl 4-(1-aminoethyl)piperidine-1-carboxylate (S)-1-Boc-3-hydroxymethyl-piperazine (S)-1-Boc-3-(hyroxymethyl)piperidine N-Boc-cis-4-Fmoc-Amino-L-proline (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (2S,4S)-BOC-4-(BOC-AMINO)-PROLINE 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI) (S)-1-BOC-3-N-(PYRIDIN-4-YLMETHYL)-AMINO-PYRROLIDINE (S)-1-BOC-3-ACETAMIDOPYRROLIDINE (S)-(+)-N-BOC-3-N-FMOC-AMINOPYRROLIDINE& (3R,4S)-1-Boc-4-Fmoc-amino-3-pyrrolidinecarboxylic acid (S,S)-3-BOC-3,6-DIAZABICYCLO[3.2.0]HEPTANE (1S,4S)-5-T-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE-2-CARBOXAMIDE tert-butyl (3S)-3-[(5-amino-6-chloropyrimidin-4-yl)amino]pyrrolidine-1-carboxylate tert-butyl (3R,4R)-3-hydroxy-4-(methylamino)pyrrolidine-1-carboxylate trans-3-Benzylamino-1-Boc-4-hydroxypyrrolidine (3AS,6AS)-TERT-BUTYL HEXAHYDROPYRROLO[3,2-B]PYRROLE-1(2H)-CARBOXYLATE TERT-BUTYL (3AS,6AS)-HEXAHYDROPYRROLO[3,4-B]PYRROLE-5(1H)-CARBOXYLATE

  • 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI)
  • (3S)-3-(Methylamino)-1-Pyrrolidinecarboxylicacid 1,1-imethylethyl ester
  • tert-Butyl-(3S)-3-(methylamino)pyrrolidine-1-carboxylate
  • 1-N-Boc-3-(S)-(Methylamino) pyrrolidine
  • 1-N-Boc-(S)-(methylamino)-pyrrolidine
  • -tert-Butyl 3-(methylamino)
  • 1-Pyrrolidinecarboxylicacid,3-(MethylaMino)-,1,1-diMethylethylester,(3S)-
  • (3S)-3-(Methylamino)-1-pyrrolidinecarboxylic acid tert-butyl ester
  • tert-butyl (S)-3-(methylamino)pyrrolidine-1-carboxylate
  • ert-butyl(3S)-3-(methylamino)pyrrolidine-1-carboxylate
  • 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(3S)-(9CI) USP/EP/BP
  • (3S)-(Methylamino)pyrrolidine-1-carboxylic acid tert-butyl ester
  • 1,1-Dimethylethyl (3S)-3-(methylamino)-1-pyrrolidinecarboxylate.
  • 147081-59-2
  • AMINOACID