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cannabigerol

Product Name
cannabigerol
CAS No.
25654-31-3
Chemical Name
cannabigerol
Synonyms
cannabigerol;Anaerobically;Cannabigerol(CBG);Cannabigerol (CRM);Cannabigerol (7CI);Cannabigerol solution;Cannabigerol (exempt preparation);(E)-2-(3,7-DiMethyl-2,6-octadienyl)-5-pentylresorc;Cannabigerol (CBG) Standard@1000 μg/mL in Methanol;(E)-2-(3,7-Dimethyl-2,6-octadienyl)-5-pentylresorcinol
CBNumber
CB41304730
Molecular Formula
C21H32O2
Formula Weight
316.48
MOL File
25654-31-3.mol
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cannabigerol Property

Melting point:
49-50 °C
Boiling point:
470.4±40.0 °C(Predicted)
Density 
0.987±0.06 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-20°C
solubility 
Soluble to 100 mM in ethanol and to 100 mM in DMSO
form 
White to off-white powder.
pka
9.71±0.40(Predicted)
InChI
InChI=1S/C21H32O2/c1-5-6-7-11-18-14-20(22)19(21(23)15-18)13-12-17(4)10-8-9-16(2)3/h9,12,14-15,22-23H,5-8,10-11,13H2,1-4H3/b17-12+
InChIKey
QXACEHWTBCFNSA-SFQUDFHCSA-N
SMILES
C1(O)=CC(CCCCC)=CC(O)=C1C/C=C(\C)/CC/C=C(/C)\C
LogP
7.470 (est)
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Safety

RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
HS Code 
9999999999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C-141
Product name
Cannabigerol solution
Purity
1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$215
Updated
2024/03/01
Cayman Chemical
Product number
15293
Product name
Cannabigerol
Purity
≥98%
Packaging
1mg
Price
$54
Updated
2024/03/01
Cayman Chemical
Product number
15293
Product name
Cannabigerol
Purity
≥98%
Packaging
5mg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
20164
Product name
Cannabigerol (CRM)
Packaging
1mg
Price
$141
Updated
2024/03/01
Cayman Chemical
Product number
15293
Product name
Cannabigerol
Packaging
50mg
Price
$540
Updated
2022/04/27
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cannabigerol Chemical Properties,Usage,Production

Description

Cannabigerol (CRM) (Item No. 20164) is a certified reference material categorized as a phytocannabinoid. This product is intended for research and forensic applications.

Uses

Cannabigerol is a partial agonist of CB2 and CB1 receptors (Ki values are 337 and 440 nM respectively). Cannabigerol also exhibits α2-adrenoceptor agonist activity (EC50 = 0.2 nM in mouse brain membra nes).

Definition

ChEBI: A natural product found in Cannabis sativa and Helichrysum species.

benefits

Cannabigerol (CBG) works to fight inflammation, pain, nausea and works to slow the proliferation of cancer cells. Research has shown it also significantly reduces intraocular eye pressure caused by glaucoma. Strains high in CBG will be beneficial treating conditions such as inflammatory bowel disease, Crohn's disease, and cancer.

General Description

A non-psychoactive cannabinoid found in Cannabis, Cannabigerol (CBG) reportedly has efficacy for medical conditions such as glaucoma and inflammatory bowel disease. This Certified Spiking Solution? is suitable for cannabigerol testing methods by HPLC, GC/MS or LC-MS/MS for forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.

Mechanism of action

Cannabigerol shares a similar mechanism of action with the cannabinoid cannabidiol, since it binds itself weakly to CB1R and CB2R and, in addition to blocking CB1R, antagonizes 5-HT1A receptor, activates alpha (2) adrenoceptors, and is a modulator of endocannabinoid signaling. CBG acts as a strong α2-adrenoceptor agonist (EC50?=?0.2?nM), while it is only a moderate 5-HT1AR competitive antagonist, and at high concentrations (10?μM), it antagonizes [35S] guanosine 5′-O-[gamma-thio]triphosphate (GTPγS) binding in mouse brain membranes stimulated with AEA or CP-55940[1].

target

TRPV | 5-HT Receptor | ROS | NOS | PPAR | IGF-1R | Antifection

storage

Store at -20°C

References

[1] Fabrizio Calapai. “Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives.” Evidence-based Complementary and Alternative Medicine (2022): 3336516.

cannabigerol Preparation Products And Raw materials

Raw materials

Preparation Products

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cannabigerol Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from cannabigerol manufacturers

Zhengzhou Anbu Chem Co.,Ltd
Product
cannabigerol 25654-31-3
Price
US $7.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1000KGS
Release date
2023-10-13
Xiamen Work-For-World Medicine Co.,Ltd.
Product
Cannabigerol 25654-31-3
Price
US $1.00-1.00/kg
Min. Order
1kg
Purity
95%HPLC
Supply Ability
kg
Release date
2024-03-27
Henan Aochuang Chemical Co.,Ltd.
Product
cannabigerol 25654-31-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-29

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