cannabigerol

ChemicalBook > CAS DataBase List > cannabigerol

Product Name: cannabigerol
CAS No.: 25654-31-3
Chemical Name: cannabigerol
Synonyms: cannabigerol;Anaerobically;Cannabigerol(CBG);Cannabigerol (CRM);Cannabigerol (7CI);Cannabigerol solution;Cannabigerol (exempt preparation);(E)-2-(3,7-DiMethyl-2,6-octadienyl)-5-pentylresorc;Cannabigerol (CBG) Standard@1000 μg/mL in Methanol;(E)-2-(3,7-Dimethyl-2,6-octadienyl)-5-pentylresorcinol
CBNumber: CB41304730
Molecular Formula: C21H32O2
Formula Weight: 316.48
MOL File: 25654-31-3.mol

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cannabigerol Property

Melting point:: 49-50 °C
Boiling point:: 470.4±40.0 °C(Predicted)
Density: 0.987±0.06 g/cm3(Predicted)
Flash point:: 9℃
storage temp.: -20°C
solubility: Soluble to 100 mM in ethanol and to 100 mM in DMSO
form: White to off-white powder.
pka: 9.71±0.40(Predicted)
InChI: InChI=1S/C21H32O2/c1-5-6-7-11-18-14-20(22)19(21(23)15-18)13-12-17(4)10-8-9-16(2)3/h9,12,14-15,22-23H,5-8,10-11,13H2,1-4H3/b17-12+
InChIKey: QXACEHWTBCFNSA-SFQUDFHCSA-N
SMILES: C1(O)=CC(CCCCC)=CC(O)=C1C/C=C(\C)/CC/C=C(/C)\C
LogP: 7.470 (est)

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Safety

RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany: 1
HS Code: 9999999999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C-141
Product name: Cannabigerol solution
Purity: 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $215
Updated: 2024/03/01

Cayman Chemical

Product number: 15293
Product name: Cannabigerol
Purity: ≥98%
Packaging: 1mg
Price: $54
Updated: 2024/03/01

Cayman Chemical

Product number: 15293
Product name: Cannabigerol
Purity: ≥98%
Packaging: 5mg
Price: $107
Updated: 2024/03/01

Cayman Chemical

Product number: 20164
Product name: Cannabigerol (CRM)
Packaging: 1mg
Price: $141
Updated: 2024/03/01

Cayman Chemical

Product number: 15293
Product name: Cannabigerol
Packaging: 50mg
Price: $540
Updated: 2022/04/27

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cannabigerol Chemical Properties,Usage,Production

Description

Cannabigerol (CRM) (Item No. 20164) is a certified reference material categorized as a phytocannabinoid. This product is intended for research and forensic applications.

Uses

Cannabigerol is a partial agonist of CB2 and CB1 receptors (Ki values are 337 and 440 nM respectively). Cannabigerol also exhibits α2-adrenoceptor agonist activity (EC50 = 0.2 nM in mouse brain membra nes).

Definition

ChEBI: A natural product found in Cannabis sativa and Helichrysum species.

benefits

Cannabigerol (CBG) works to fight inflammation, pain, nausea and works to slow the proliferation of cancer cells. Research has shown it also significantly reduces intraocular eye pressure caused by glaucoma. Strains high in CBG will be beneficial treating conditions such as inflammatory bowel disease, Crohn's disease, and cancer.

General Description

A non-psychoactive cannabinoid found in Cannabis, Cannabigerol (CBG) reportedly has efficacy for medical conditions such as glaucoma and inflammatory bowel disease. This Certified Spiking Solution^? is suitable for cannabigerol testing methods by HPLC, GC/MS or LC-MS/MS for forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.

Mechanism of action

Cannabigerol shares a similar mechanism of action with the cannabinoid cannabidiol, since it binds itself weakly to CB1R and CB2R and, in addition to blocking CB1R, antagonizes 5-HT1A receptor, activates alpha (2) adrenoceptors, and is a modulator of endocannabinoid signaling. CBG acts as a strong α2-adrenoceptor agonist (EC50?=?0.2?nM), while it is only a moderate 5-HT1AR competitive antagonist, and at high concentrations (10?μM), it antagonizes [35S] guanosine 5′-O-[gamma-thio]triphosphate (GTPγS) binding in mouse brain membranes stimulated with AEA or CP-55940[1].

target

storage

Store at -20°C

References

[1] Fabrizio Calapai. “Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives.” Evidence-based Complementary and Alternative Medicine (2022): 3336516.

cannabigerol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from cannabigerol manufacturers

Zhengzhou Anbu Chem Co.,Ltd

Product: cannabigerol 25654-31-3
Price: US $7.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000KGS
Release date: 2023-10-13

Xiamen Work-For-World Medicine Co.,Ltd.

Product: Cannabigerol 25654-31-3
Price: US $1.00-1.00/kg
Min. Order: 1kg
Purity: 95%HPLC
Supply Ability: kg
Release date: 2024-03-27

Henan Aochuang Chemical Co.,Ltd.

Product: cannabigerol 25654-31-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-29

25654-31-3, cannabigerolRelated Search:

Hydroxytyrosol Cannabidivarol Hydroxytyrosol Acetate Ellagic acid Chebulinic acid 10-Gingerol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one 3,4-Dimethoxybenzyl alcohol chebulagic acid Chebulic Acid 3,4-Dimethoxybenzoic acid CANNABIDIOL Sodium phosphate dibasic dodecahydrate cannabigerol

cannabigerol

Cannabigerol (exempt preparation)

Cannabigerol solution

2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol

Cannabigerol (CRM)

2-[(2E)-3,7-Dimethyl-2,6-octadienyl]-5-pentylresorcinol

2-[(E)-3,7-Dimethyl-2,6-octadienyl]-5-pentyl-1,3-benzenediol

1,3-Benzenediol, 2-[(2E)-3,7-diMethyl-2,6-octadien-1-yl]-5-pentyl-

(E)-2-(3,7-DiMethyl-2,6-octadienyl)-5-pentyl-1,3-benzenediol

(E)-2-(3,7-DiMethyl-2,6-octadienyl)-5-pentylresorc

2-[(2E)-3,7-DiMethyl-2,6-octadien-1-yl]-5-pentyl-1,3-benzenediol

2-[(2E)-3,7-DiMethyl-2,6-octadienyl]-5-pentyl-1,3-benzenediol

(E)-2-(3,7-Dimethyl-2,6-octadienyl)-5-pentylresorcinol

Cannabigerol(CBG)

Cannabigerol (CBG) Standard@1000 μg/mL in Methanol

Anaerobically

CannabigerolQ: What is Cannabigerol Q: What is the CAS Number of Cannabigerol

Cannabigerol (7CI)

colorectal,5-hydroxytryptamine Receptor,Adrenergic Receptor,ROS,anti-cancer,viability,Cannabinoid Receptor,mRNA,Inhibitor,5-HT Receptor,Transient receptor potential channels,CHOP,Apoptosis,Cannabigerol,inhibit,TRP Channel,cancer,Serotonin Receptor,Beta Receptor

2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5-pentylbenzene-1,3-diol

25654-31-3