2-IODO-5-METHOXYANILINE
- Product Name
- 2-IODO-5-METHOXYANILINE
- CAS No.
- 153898-63-6
- Chemical Name
- 2-IODO-5-METHOXYANILINE
- Synonyms
- 2-IODO-5-METHOXYANILINE;2-Iodo-5-methoxybenzenamine;2-Iodo-5-methoxy-phenylamine;BenzenaMine, 2-iodo-5-Methoxy-;1H-Pyrazol-5-amine,1-(3-methylethyl)-
- CBNumber
- CB4130950
- Molecular Formula
- C7H8INO
- Formula Weight
- 249.05
- MOL File
- 153898-63-6.mol
2-IODO-5-METHOXYANILINE Property
- Melting point:
- 33-36 °C(Solv: ethyl acetate (141-78-6))
- Boiling point:
- 298.4±30.0 °C(Predicted)
- Density
- 1.807±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- 2.11±0.10(Predicted)
- Appearance
- White to light brown Solid
- InChI
- InChI=1S/C7H8INO/c1-10-5-2-3-6(8)7(9)4-5/h2-4H,9H2,1H3
- InChIKey
- CYDBBGSUZRDOPE-UHFFFAOYSA-N
- SMILES
- C1(N)=CC(OC)=CC=C1I
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I708655
- Product name
- 2-Iodo-5-methoxyaniline
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- W3349
- Product name
- 2-Iodo-5-methoxyaniline
- Packaging
- 5g
- Price
- $444
- Updated
- 2021/12/16
- Product number
- HCH0049825
- Product name
- 2-IODO-5-METHOXYANILINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $852.55
- Updated
- 2021/12/16
- Product number
- HCH0049825
- Product name
- 2-IODO-5-METHOXYANILINE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1227.82
- Updated
- 2021/12/16
- Product number
- HCH0049825
- Product name
- 2-IODO-5-METHOXYANILINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1548.26
- Updated
- 2021/12/16
2-IODO-5-METHOXYANILINE Chemical Properties,Usage,Production
Synthesis
58755-70-7
153898-63-6
General procedure for the synthesis of 2-iodo-5-methoxyaniline from 4-iodo-3-nitroanisole: To a 100 mL methanol solution of 4-iodo-3-nitroanisole (5 g, 17.9 mmol) was added FeCl3 (50 mg, 0.3 mmol) and activated carbon (40 mg). The mixture was heated to reflux and hydrazine hydrate (1.75 g, 35 mmol) was added slowly and dropwise. After keeping the reaction at reflux for 8 h, it was cooled to room temperature and the reaction mixture was filtered through diatomaceous earth. The filtrate was concentrated and purified by column chromatography (eluent: hexane solution of 10% ethyl acetate) to afford 4.05 g of the target product 2-iodo-5-methoxyaniline as a light yellow oil (91% yield).1H NMR (300 MHz, CDCl3) δ 7.47 (1H, d, J = 8.7 Hz), 6.31 (1H, d, J = 2.8 Hz), 6.13 (1H, d, J = 2.8 Hz) 6.13 (1H, dd, J = 2.8, 8.7 Hz), 3.73 (3H, s).
References
[1] Angewandte Chemie - International Edition, 2011, vol. 50, # 32, p. 7354 - 7358
[2] Journal of Organic Chemistry, 2001, vol. 66, # 13, p. 4525 - 4542
[3] Patent: WO2003/106462, 2003, A1. Location in patent: Page 110
[4] Tetrahedron Letters, 2008, vol. 49, # 2, p. 363 - 366
[5] Angewandte Chemie - International Edition, 2010, vol. 49, # 48, p. 9262 - 9265
2-IODO-5-METHOXYANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-IODO-5-METHOXYANILINE Suppliers
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
View Lastest Price from 2-IODO-5-METHOXYANILINE manufacturers
- Product
- 2-IODO-5-METHOXYANILINE 153898-63-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kgs
- Release date
- 2020-01-28