Zearalenone

Product Name: Zearalenone
CAS No.: 17924-92-4
Chemical Name: Zearalenone
Synonyms: ZEN;ZON;(s)-zearalenone;RAL;(-)-Zearalenone;[S-(E)]-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione;ZENONE;toxinf2;f-2toxin;(3S,11E)-
CBNumber: CB4131407
Molecular Formula: C18H22O5
Formula Weight: 318.36
MOL File: 17924-92-4.mol

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Zearalenone Property

Melting point:: 164-165°C
alpha: 25546 -170.5° (c = 1.0 in CH3OH)
Boiling point:: 377.53°C (rough estimate)
Density: 1.1270 (rough estimate)
refractive index: 1.6120 (estimate)
Flash point:: 6 °C
storage temp.: 2-8°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.12 mg/ml; Ethanol: 20 mg/ml
pka: 7.58±0.40(Predicted)
form: Solid
color: Off-white
Merck: 13,10169
BRN: 1350216
InChIKey: MBMQEIFVQACCCH-QBODLPLBSA-N
LogP: 3.830 (est)
CAS DataBase Reference: 17924-92-4(CAS DataBase Reference)
EPA Substance Registry System: Zearalenone (17924-92-4)

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Safety

Hazard Codes: C,Xn,F
Risk Statements: 34-62-63-36-20/21/22-11
Safety Statements: 26-36/37/39-45-36-16-36/37
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
RTECS: DM2550000
F: 10
HS Code: 29322090
Hazardous Substances Data: 17924-92-4(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CRM46916
Product name: Zearalenone solution
Purity: certified reference material, 50?μg/mL in acetonitrile, ampule of 1?mL
Packaging: 1mL
Price: $111
Updated: 2024/03/01

Sigma-Aldrich

Product number: 34126
Product name: Zearalenone solution
Purity: 100 μg/mL in acetonitrile, analytical standard
Packaging: 2ml
Price: $488
Updated: 2024/03/01

Sigma-Aldrich

Product number: 32939
Product name: Zearalenone
Purity: reference material
Packaging: 5mg
Price: $689
Updated: 2022/05/15

Cayman Chemical

Product number: 11353
Product name: Zearalenone
Purity: ≥98%
Packaging: 5mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 11353
Product name: Zearalenone
Purity: ≥98%
Packaging: 10mg
Price: $73
Updated: 2024/03/01

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Zearalenone Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

Zearalenone is a resorcylic acid lactone produced by a number of Fusarium sp.. Zearalenone acts as a non-steroidal estrogen, binding to estrogen receptor and is uterotropic. Zearalenone induces reproductive problems in animals and, in some animal models, is thought to be a primary initiator of hepatic tumours. In vivo, zearalenone undergoes metabolic reduction to the more estrogenic zearalenol. Contamination of grains, notably maize, by Fusarium species gives rise to high levels of zearalenone and is regarded as an important food quality issue for both humans and animal health.

Uses

A phytoestrogenic mycotoxin and ER activator

Uses

Estrogenic mycotoxin produced by Fusarium fungi commonly found in grains. One of a group of compounds known as resorcylic acid lactones

Definition

ChEBI: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.

General Description

White microcrystals or white powder.

Air & Water Reactions

Zearalenone may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

Zearalenone is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Zearalenone may be incompatible with alkalis.

Fire Hazard

Flash point data for Zearalenone are not available. Zearalenone is probably combustible.

Biochem/physiol Actions

Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.

Metabolic pathway

When zearalenone is subjected to microbial transformation by a fungus, Gliocladium roseum, it is converted to a 1 : 1 mixture of 1-(3,5-dihydroxyphenyl)- 10 0 -hydroxy-1-undecen-6'-one and 1-(3,5- dihydroxyphenyl)-6'-hydroxy-1-undecen-10'-one.

storage

-20°C

Zearalenone Preparation Products And Raw materials

Raw materials

Preparation Products

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Zearalenone Suppliers

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View Lastest Price from Zearalenone manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Zearalenone 17924-92-4
Price: US $0.00-0.00/KG
Min. Order: 100g
Purity: 99.0%+
Supply Ability: 100 tons
Release date: 2020-01-19

Career Henan Chemical Co

Product: Zearalenone 17924-92-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 1000kg
Release date: 2018-12-25

17924-92-4, ZearalenoneRelated Search:

Thiophanate-methyl Androstenedione Clethodim Bensulfuron methyl Methyl salicylate 2-Cyclohexen-1-one Trenbolone Zeranol Methylparaben Kresoxim-methyl Methyl acetate Quinocetone METSULFURON METHYL Zein trans-Zeatin TRANS-ZEATIN RIBOSIDE ZEARALANONE CORN OIL

(E)-(S)-2,4-DIHYDROXY-7-METHYL-7,8,9,10,13,14-HEXAHYDRO-12H-6-OXA-BENZOCYCLOTETRADECENE-5,11-DIONE

ZON

ZENONE

ZEARALENONE

(10s)-zearalenone

(e)--methyl-7-oxo

(s-(e))-xy-3-methyl

(s)-zearalenone

3,4,5,6,9,10-HEXAHYDRO-14,16-DIHYDROXY-3-METHYL-1H-2-BENZOXACYCLOTETRADECIN-1,7(8H)-DIONE

MYCOTOXIN F2

Zearalenone, froM Giberella zeae

(2E,11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,15,17-tetraene-7,13-dione

Zearalenone, >=98%

Zearalenone [S-(E)]-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione

ZEARALENONE, FUNGAL MYCOTOXIN

14,16-Dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione

Zearalenone( F-2 toxin)

Zearalenone, 98%, from Giberella zeae

[s-(e)]-xy-3-methyl

16-dihydroxy-3-methyl-7-oxo-1trans-benzoxacyclotetradec-11-en-1-on

1h-2-benzoxacyclotetradecin-1,7(8h)-dione,3,4,5,6,9,10-hexahydro-14,16-dihydro

1h-2-benzoxacyclotetradecin-1-one,3,4,5,6,7,8,9,10-octahydro-14,16-dihydroxy-3

3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1h-2-benzoxacyclotetradecin-1,

6-(10-hydroxy-6-oxo-1-undecenyl)-,mu-lactone,trans-resorcylicaci

6-(10-hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylicacidlactone

6-(10-hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylicacid-n-lactone

7(8h)-dione

compoundf-2

f-2toxin

fusariumtoxin

nci-c50226

toxinf2

trans-zearalenone

[S-(E)]-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione

zearalenone solution

3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2- benzoxacyclotetradecin-1,7(8H)-dione, FES, Compound F-2, Toxin F2

(3S,11E)-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2 -benzoxacyclotetradecin-1,7(8H)-dione

rac Zearalenone-d6

1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (3S,11E)-

Zearalenone solution,ZON

(3S,11E)-

(S,E)-14,16-dihydroxy-3-Methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione

Mycotoxin F2, Toxin F2

ZEN

Zearalenone in corn, mid level

Zearalenone Standard

Zearalenone in corn, high level

Zearalenone in corn, low level

Zearalenone Solution (100μg/ml Acetonitrile Solution)

RAL

Zearalenone Ready Made Solution

Zearalenone 100ug/ml in ACN

Zearalenone Solution in Methanol, 100μg/mL

Zearalenone Solution in Acetonitrile, 100μg/mL

(-)-Zearalenone

Zearalenone USP/EP/BP

earalenone

Zearalenone (Mycotoxin F2