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licarin B

Product Name
licarin B
CAS No.
51020-87-2
Chemical Name
licarin B
Synonyms
licarin B;Licarine B;(-)-Licarin B;5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole;5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole;5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole;1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-;1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI);5-((2R,3R)-7-Methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
CBNumber
CB41314632
Molecular Formula
C20H20O4
Formula Weight
324.37
MOL File
51020-87-2.mol
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licarin B Property

Boiling point:
428.5±45.0 °C(Predicted)
Density 
1.201±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
N1572
Product name
(-)-LicarinB
Packaging
20mg
Price
$250
Updated
2021/12/16
AK Scientific
Product number
Y1205
Product name
licarinB
Packaging
25mg
Price
$336
Updated
2021/12/16
Crysdot
Product number
CD11113736
Product name
LicarinB
Purity
97%
Packaging
50mg
Price
$353
Updated
2021/12/16
Chemenu
Product number
CM161067
Product name
5-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
Purity
97%
Packaging
100mg
Price
$468
Updated
2021/12/16
Crysdot
Product number
CD11113736
Product name
LicarinB
Purity
97%
Packaging
100mg
Price
$641
Updated
2021/12/16
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licarin B Chemical Properties,Usage,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from nutmeg, Lauraceae (Lauraceae) Licarin aritu Ducke trunk (yield: 0.35%) Machilus japonica Sieb.et Zucc. Ye Hongnan Machilus thunbergii Sieb.et Zucc. Bark, wood, leaves.

Uses

Licarin B has antibacterial, anti-inflammatory, sedative and anti-tumor effects.

Biological Activity

Licarin B, derived from the seeds of Myristica fragrans, is an inhibitor of NO production and improves insulin sensitivity by activating PPARγ and GLUT4 in the IRS-1/PI3K/AKT pathway.

in vitro

Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes.

Cell Viability Assay < /p>

Cell Line: 3T3-L1 cell.
Concentration: 1-500 μM.
Incubation Time: 48 h.
Result: Did not cause significant cell death up to 500 μM concentration.

Cell Viability Assay

td>
Cell Line: 3T3-L1 cell.
Concentration: 5 μM, 10 μM, 15 μM.
Incubation Time: 8 days (replaced every 2 days). 8 days (replaced every 2 days).
Result: LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation.
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target

PPAR | GLUT | PI3K | Akt | IRS-1

licarin B Preparation Products And Raw materials

Raw materials

Preparation Products

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licarin B Suppliers

Jiangsu Yongjian Pharmaceutical Technology Co., Ltd
Tel
17701422015
Email
3582572959@qq.com
Country
China
ProdList
696
Advantage
58
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
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View Lastest Price from licarin B manufacturers

Shanghai Standard Technology Co., Ltd.
Product
(-)-Licarin B 51020-87-2
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-12
Career Henan Chemical Co
Product
licarin B 51020-87-2
Price
US $1.00/kg
Min. Order
1 mg
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

51020-87-2, licarin BRelated Search:


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