ChemicalBook > CAS DataBase List > licarin B

licarin B

Product Name
licarin B
CAS No.
51020-87-2
Chemical Name
licarin B
Synonyms
licarin B;Licarine B;(-)-Licarin B;5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole;5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole;5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole;1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-;1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI);5-((2R,3R)-7-Methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
CBNumber
CB41314632
Molecular Formula
C20H20O4
Formula Weight
324.37
MOL File
51020-87-2.mol
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licarin B Property

Boiling point:
428.5±45.0 °C(Predicted)
Density 
1.201±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
N1572
Product name
(-)-LicarinB
Packaging
20mg
Price
$250
Updated
2021/12/16
AK Scientific
Product number
Y1205
Product name
licarinB
Packaging
25mg
Price
$336
Updated
2021/12/16
Crysdot
Product number
CD11113736
Product name
LicarinB
Purity
97%
Packaging
50mg
Price
$353
Updated
2021/12/16
Chemenu
Product number
CM161067
Product name
5-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
Purity
97%
Packaging
100mg
Price
$468
Updated
2021/12/16
Crysdot
Product number
CD11113736
Product name
LicarinB
Purity
97%
Packaging
100mg
Price
$641
Updated
2021/12/16
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licarin B Chemical Properties,Usage,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from nutmeg, Lauraceae (Lauraceae) Licarin aritu Ducke trunk (yield: 0.35%) Machilus japonica Sieb.et Zucc. Ye Hongnan Machilus thunbergii Sieb.et Zucc. Bark, wood, leaves.

Uses

Licarin B has antibacterial, anti-inflammatory, sedative and anti-tumor effects.

Biological Activity

Licarin B, derived from the seeds of Myristica fragrans, is an inhibitor of NO production and improves insulin sensitivity by activating PPARγ and GLUT4 in the IRS-1/PI3K/AKT pathway.

in vitro

Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes.

Cell Viability Assay < /p>

Cell Line: 3T3-L1 cell.
Concentration: 1-500 μM.
Incubation Time: 48 h.
Result: Did not cause significant cell death up to 500 μM concentration.

Cell Viability Assay

td>
Cell Line: 3T3-L1 cell.
Concentration: 5 μM, 10 μM, 15 μM.
Incubation Time: 8 days (replaced every 2 days). 8 days (replaced every 2 days).
Result: LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation.
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target

PPAR | GLUT | PI3K | Akt | IRS-1

licarin B Preparation Products And Raw materials

Raw materials

Preparation Products

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licarin B Suppliers

China 123 India 1 United States 12 Global 136
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
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United States
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ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
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55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
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60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
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58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52925
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58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
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58
ApexBio Technology
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Email
sales@apexbt.com
Country
United States
ProdList
6251
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58
Alfa Chemistry
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Email
info@Alfa-Chemistry.com
Country
United States
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MedChemExpress
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Email
sales@medchemexpress.com
Country
United States
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Combi-Blocks Inc.
Tel
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sales@combi-blocks.com
Country
United States
ProdList
6618
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69
Biorbyt Ltd.
Tel
--
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Email
info@biorbyt.com
Country
United States
ProdList
6926
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FortopChem Technology Limited
Tel
--
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Email
sales@fortopchem.com
Country
United States
ProdList
1099
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View Lastest Price from licarin B manufacturers

Shanghai Standard Technology Co., Ltd.
Product
(-)-Licarin B 51020-87-2
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-12
Career Henan Chemical Co
Product
licarin B 51020-87-2
Price
US $1.00/kg
Min. Order
1 mg
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

51020-87-2, licarin BRelated Search:

beta-Eudesmol MONOMYRISTIN MOSLOFLAVONE ALPHA-CARYOPHYLLENE Myristic acid 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one beta-Sitosterol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol Eugenol alpha-Cyperone Hydroxyecdysone alpha-Terpineol Myristicin Artemether hydroxygenkwanin 4-[(2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-2-methoxyphenol TRIMYRISTIN

  • 1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI)
  • licarin B
  • 5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole
  • 5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole
  • 5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole
  • Licarine B
  • 1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-
  • (-)-Licarin B
  • 5-((2R,3R)-7-Methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
  • 51020-87-2
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • reagent
  • standard substance