ChemicalBook > CAS DataBase List > 3,5-Bis(trifluoromethyl)bromobenzene
3,5-Bis(trifluoromethyl)bromobenzene
- Product Name
- 3,5-Bis(trifluoromethyl)bromobenzene
- CAS No.
- 328-70-1
- Chemical Name
- 3,5-Bis(trifluoromethyl)bromobenzene
- Synonyms
- 1-BROMO-3,5-BIS(TRIFLUOROMETHYL)BENZENE;3,5-BIS(TRIFLUOROMETHYL)-1-BROMOBENZENE;1,3-BIS(TRIFLUOROMETHYL)-5-BROMOBENZENE;3,5-Bis(trifluoromethyl)phenyl bromide;MBT-BR;1,3-Bis(trifL;1-BROMO-3,5-BIS;)-5-bromobenzene;TRIFLUOROMETHYL BROMOBENZENE;3,5-Bis(trifluoromethly)b...
- CBNumber
- CB4137843
- Molecular Formula
- C8H3BrF6
- Formula Weight
- 293
- MOL File
- 328-70-1.mol
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3,5-Bis(trifluoromethyl)bromobenzene Property
- Melting point:
- −16 °C(lit.)
- Boiling point:
- 154 °C(lit.)
- Density
- 1.699 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.427(lit.)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Sparingly)
- form
- Liquid
- Specific Gravity
- 1.699
- color
- Clear colorless to slightly yellow
- Water Solubility
- Immiscible with water.
- BRN
- 2123669
- InChIKey
- CSVCVIHEBDJTCJ-UHFFFAOYSA-N
- CAS DataBase Reference
- 328-70-1(CAS DataBase Reference)
- NIST Chemistry Reference
- 3,5-Bis(trifluoromethyl)bromobenzene(328-70-1)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 37/39-26-36-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29036990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 290157
- Product name
- 1,3-Bis(trifluoromethyl)-5-bromobenzene
- Purity
- 99%
- Packaging
- 10g
- Price
- $60.41
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 290157
- Product name
- 1,3-Bis(trifluoromethyl)-5-bromobenzene
- Purity
- 99%
- Packaging
- 50g
- Price
- $149.41
- Updated
- 2025/07/31
TCI Chemical
- Product number
- B1753
- Product name
- 1-Bromo-3,5-bis(trifluoromethyl)benzene
- Purity
- >98.0%(GC)
- Packaging
- 10g
- Price
- $16
- Updated
- 2025/07/31
TCI Chemical
- Product number
- B1753
- Product name
- 1-Bromo-3,5-bis(trifluoromethyl)benzene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $29
- Updated
- 2025/07/31
TRC
- Product number
- B412888
- Product name
- 3,5-Bis(trifluoromethyl)bromobenzene
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
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3,5-Bis(trifluoromethyl)bromobenzene Chemical Properties,Usage,Production
Chemical Properties
clear colourless to slightly yellow liquid
Uses
1,3-Bis(trifluoromethyl)-5-bromobenzene is used to prepare the tetrakis[3,5-bis(trifluoromethyl)phenyl]borate ion, which acts as a stabilizing counterion for electrophilic organic and organometallic cations.
Synthesis Reference(s)
The Journal of Organic Chemistry, 68, p. 3695, 2003 DOI: 10.1021/jo026903n
Synthesis
402-31-3
328-70-1
Example 1: 1,3-bis(trifluoromethyl)benzene (1 kg) was slowly added to concentrated sulfuric acid (4 kg) while stirring the reaction mixture. The mixture was cooled to 5°C and 1,3-dibromo-5,5-dimethylglycolide (DBDMH, 668g) was added in batches over a period of 4 hours while maintaining the temperature between 0°C and 10°C. After completion of the reaction, the mixture was allowed to stand and layered to separate the organic phase. The organic phase was washed sequentially with water and dilute sodium bisulfite solution to remove residual acid and oxidants. Finally, the organic phase was purified by fractional distillation to afford 3,5-bis(trifluoromethyl)bromobenzene (1100 g, 99% purity, 80% yield).
References
[1] Journal of Organic Chemistry, 2003, vol. 68, # 9, p. 3695 - 3698
[2] Journal of Organic Chemistry USSR (English Translation), 1991, vol. 27, # 1.2, p. 108 - 112
[3] Zhurnal Organicheskoi Khimii, 1991, vol. 27, # 1, p. 125 - 129
[4] Tetrahedron Letters, 1998, vol. 39, # 52, p. 9621 - 9622
[5] Synlett, 1999, # 8, p. 1245 - 1246
3,5-Bis(trifluoromethyl)bromobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Bis(trifluoromethyl)bromobenzene manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- 3,5-Bis(trifluoromethyl)bromobenzene 328-70-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-04
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- 3,5-Bis(trifluoromethyl)bromobenzene 328-70-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-12
Speranza Chemical Co., Ltd.
- Product
- 1-bromo-3,5-bis(trifluoromethyl)benzene 328-70-1
- Price
- US $50.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 20 tons
- Release date
- 2019-12-24
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