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HEXAHYDROCURCUMIN

Product Name
HEXAHYDROCURCUMIN
CAS No.
36062-05-2
Chemical Name
HEXAHYDROCURCUMIN
Synonyms
HEXAHYDROCURCUMIN;Hexahydrocurcumin-RM;Hexahydrocurcumin, BR;5-dimethyl ether Gallic Acid;5-dimethoxy-4-hydroxy Benzoic Acid;5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone;1,7-Bis(4-hydroxy-3-methoxyphenyl)-5-hydroxyheptan-3-one;1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-3-heptanone;5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan-3-one;3-Heptanone, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-
CBNumber
CB41412369
Molecular Formula
C21H26O6
Formula Weight
374.43
MOL File
36062-05-2.mol
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HEXAHYDROCURCUMIN Property

Melting point:
80-82℃
Boiling point:
622.6±55.0 °C(Predicted)
Density 
1.226
Flash point:
218℃
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly), DCM, DMSO
form 
Solid
pka
10.02±0.20(Predicted)
color 
Pale Yellow
BRN 
2486876
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB01366
Product name
Hexahydrocurcumin
Purity
≥95% (HPLC)
Packaging
1MG
Price
$124
Updated
2024/03/01
Sigma-Aldrich
Product number
SMB01366
Product name
Hexahydrocurcumin
Purity
≥95% (HPLC)
Packaging
10MG
Price
$744
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL82559
Product name
Hexahydrocurcumin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$975
Updated
2024/03/01
Sigma-Aldrich
Product number
69727
Product name
Hexahydrocurcumin
Purity
analytical standard
Packaging
10mg
Price
$835
Updated
2024/03/01
Cayman Chemical
Product number
11714
Product name
Hexahydrocurcumin
Purity
≥95%
Packaging
1mg
Price
$86
Updated
2024/03/01
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HEXAHYDROCURCUMIN Chemical Properties,Usage,Production

Description

Hexahydrocurcumin is a natural product and glucuronide metabolite of curcumin that has anti-inflammatory, antioxidant, and anticancer properties. It reduces prostaglandin E2 (PGE2) production stimulated by phorbol 12-myristate 13-acetate (PMA; ) by 37% in human colonic epithelial cells when used at a concentration of 20 μM. Hexahydrocurcumin (3.125-25 μM) inhibits overproduction of nitric oxide induced by LPS in RAW 264.7 macrophage cells in a concentration-dependent manner. It does not affect LPS-induced cytokine release but inhibits LPS-induced iNOS and COX-2 upregulation and NF-κB activation when used at a concentration of 50 μM. Hexahydrocurcumin prevents the formation of aberrant crypt foci in a dimethylhydrazine rat model of colon cancer and potentiates the effect of 5-fluorouracil .

Uses

Hexahydrocurcumin is an intermediate in the synthesis of Gingerenone A (G387500) which is an antifungal and antiparasitic diarylheptenone that is isolated from Zingiber officinale (more commonly known as ginger), a medicinal plant that is used to treat inflammation and musculoskeletal disorders.

Definition

ChEBI: Hexahydrocurcumin is a diarylheptanoid.

target

PGE | NOS | COX

HEXAHYDROCURCUMIN Preparation Products And Raw materials

Raw materials

Preparation Products

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HEXAHYDROCURCUMIN Suppliers

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View Lastest Price from HEXAHYDROCURCUMIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Hexahydrocurcumin 36062-05-2
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-09
Henan Aochuang Chemical Co.,Ltd.
Product
HEXAHYDROCURCUMIN 36062-05-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13

36062-05-2, HEXAHYDROCURCUMINRelated Search:

Phosphorus pentachloride CHEBULAE FRUCTUS IMMATURUS DEMETHOXYCURCUMIN BIS(4-HYDROXYCINNAMOYL)METHANE 5"-MethoxyhexahydrocurcuMin (3S,5S)-1,7-BIS(4-HYDROXY-3-METHOXYPHENYL)HEPTANE-3,5-DIOL FLLL31 DihydrocurcuMin Curcumin ASC-J9 Tetrahydrocurcumin TetrahydrocucuMin Hexahydropyridazin

  • HEXAHYDROCURCUMIN
  • 5-Hydroxy-1-(4-hydroxy-3-Methoxycyclohexyl)-7-(4-hydroxy-3-Methoxyphenyl)heptan-3-one
  • (RS)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone
  • 1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-3-heptanone
  • 1,7-Bis(4-hydroxy-3-methoxyphenyl)-5-hydroxyheptan-3-one
  • 5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone
  • Hexahydrocurcumin, BR
  • 3-Heptanone, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-
  • 5-dimethoxy-4-hydroxy Benzoic Acid
  • 5-dimethyl ether Gallic Acid
  • 5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan-3-one
  • Hexahydrocurcumin-RM
  • 36062-05-2