ChemicalBook > CAS DataBase List > 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- Product Name
- 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- CAS No.
- 1434-54-4
- Chemical Name
- 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- Synonyms
- pcn;sc4674;U-14975;16-alpha-cyanopregnenolone;pregnenolone-16α-carbonitrile;Pregnenolone 16α-carbonitrile;5-PREGNEN-16α-CYANO-3β-OL-20-ONE;PREGNENOLONE-16ALPHA-CARBONITRILE;16α-Cyano-3β-hydroxypregn-5-en-20-one;5-pregnen-3B-ol-20-one-16A-carbonitrile
- CBNumber
- CB4150567
- Molecular Formula
- C22H31NO2
- Formula Weight
- 341.49
- MOL File
- 1434-54-4.mol
More
Less
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Property
- Melting point:
- 225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2))
- Boiling point:
- 508.5±50.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- Flash point:
- 93 °C
- storage temp.
- 2-8°C
- solubility
- Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
- form
- White to off-white solid.
- pka
- 14.95±0.70(Predicted)
- color
- White to off-white
- EPA Substance Registry System
- Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)
More
Less
Safety
- WGK Germany
- 3
- RTECS
- TU4536500
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- P0543
- Product name
- 5-Pregnen-3β-ol-20-one-16α-carbonitrile
- Purity
- ≥97%
- Packaging
- 50mg
- Price
- $83.5
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P0543
- Product name
- 5-Pregnen-3β-ol-20-one-16α-carbonitrile
- Purity
- ≥97%
- Packaging
- 100mg
- Price
- $150
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 16343
- Product name
- Pregnenolone Carbonitrile
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $40
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 16343
- Product name
- Pregnenolone Carbonitrile
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $64
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P0543
- Product name
- 5-Pregnen-3β-ol-20-one-16α-carbonitrile
- Purity
- ≥97%
- Packaging
- 250mg
- Price
- $290
- Updated
- 2024/03/01
More
Less
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Chemical Properties,Usage,Production
Uses
Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
Definition
ChEBI: Pregnenolone 16alpha-carbonitrile is an aliphatic nitrile. It is functionally related to a pregnenolone.
Biochem/physiol Actions
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
1434-54-4, 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILERelated Search:
CYCLOPENTANECARBONITRILE
2-METHYLDECANONITRILE
N-DODECYL CYANIDE
Dodecanenitrile
N-OCTYL CYANIDE
3-METHYLDODECANONITRILE
ORANILE
Decanonitrile
ISOCAPRONITRILE
3-Methylbutanenitrile
OCTANENITRILE
Pregnenolone
6-METHYLHEPTANENITRILE
7-OCTENENITRILE
16-ALPHA-METHYLPREGNENOLONE
3-METHYLVALERONITRILE
2-PROPYLVALERONITRILE
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE