N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol

Product Name: N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol
CAS No.: 82689-20-1
Chemical Name: N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol
Synonyms: Boc-K(Z)-OL;Boc-L-Lys(Z)-ol;Boc-Lys(Cbz)-Ol;Boc-L-Lysinol(Z);Boc-L-Lys(Cbz)-OL;Boc-Lysinol(Z)-OH;N-BOC-N'-CBZ-lysine;Na-Boc-Ne-Z-L-lysinol≥ 98% (HPLC);N-alpha-Boc-N-epsilon-Cbz-L-lysinol;(S)-Benzyl tert-butyl (6-hydroxyhexane-1,5-diyl)dicarbaMate
CBNumber: CB41511068
Molecular Formula: C19H30N2O5
Formula Weight: 366.45
MOL File: 82689-20-1.mol

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N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol Property

Melting point:: 62-63℃
Boiling point:: 551.4±50.0 °C(Predicted)
Density: 1.122±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 12.06±0.46(Predicted)
InChI: InChI=1S/C19H30N2O5/c1-19(2,3)26-18(24)21-16(13-22)11-7-8-12-20-17(23)25-14-15-9-5-4-6-10-15/h4-6,9-10,16,22H,7-8,11-14H2,1-3H3,(H,20,23)(H,21,24)/t16-/m0/s1
InChIKey: MLAPMZGXJGUYNO-INIZCTEOSA-N
SMILES: C(OCC1=CC=CC=C1)(=O)NCCCC[C@H](NC(OC(C)(C)C)=O)CO

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B656925
Product name: Boc-Lysinol(Z)
Packaging: 5g
Price: $330
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0002467
Product name: BOC-L-LYSINOL(Z)
Purity: 95.00%
Packaging: 5MG
Price: $495.92
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 37545
Product name: Boc-Lysinol(Z)
Packaging: 5G
Price: $550
Updated: 2021/12/16

Iris Biotech GmbH

Product number: BAL1040
Product name: Boc-L-Lys(Z)-ol
Packaging: 5G
Price: $607.5
Updated: 2021/12/16

Chem-Impex

Product number: 03200
Product name: Nα-Boc-Nε-Z-L-lysinol,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 25G
Price: $666.4
Updated: 2021/12/16

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N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Boc-Lysinol(Z) is used to prepare N-(iminoethyl)lysinol derivs. as nitric oxide synthase inhibitors.

Synthesis

2389-45-9

82689-20-1

GENERAL METHODS: To a solution of N-Boc-N'-Cbz-L-lysine (10 mmol) in THF (10 mL) was added DIPEA (11 mmol, 1.42 mL) and EtOAc solution of 50% T3P (20 mmol, 6.36 mL) at 0 °C with stirring for about 10 min. Then NaBH4 aqueous solution (10 mmol, 388 mg, dissolved in 0.3 mL H2O) was slowly added to the reaction mixture at the same temperature, and the progress of the reaction was monitored by TLC until the reaction was completed. After completion of the reaction, the solvent was removed by evaporation under reduced pressure and the crude product was extracted with EtOAc. The organic phase was washed sequentially with 5% aqueous citric acid (10 mL × 2), 5% aqueous Na2CO3 (10 mL × 2), water and saturated saline. The organic layer was dried over anhydrous Na2SO4 and concentrated under reduced pressure to give (S)-tert-butylbenzyl (6-hydroxyhexane-1,5-diyl) dicarbamate.

References

[1] Tetrahedron Asymmetry, 2015, vol. 26, # 21-22, p. 1273 - 1280
[2] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5059 - 5063
[3] Synlett, 1999, # 8, p. 1239 - 1240
[4] Chemical and Pharmaceutical Bulletin, 1982, vol. 30, # 5, p. 1921 - 1924
[5] Tetrahedron Letters, 1991, vol. 32, # 7, p. 923 - 926

N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol Preparation Products And Raw materials

Raw materials

Preparation Products

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N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol Suppliers

China 47 Germany 1 India 3 Japan 1 United Kingdom 2 United States 5 Global 59

Shanghai Sunway Pharmaceutical Technology Co., Ltd

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View Lastest Price from N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-Lys(Cbz)-Ol 82689-20-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-01-17

Career Henan Chemical Co

Product: N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol 82689-20-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10tons
Release date: 2020-02-18

Sichuan Jiaying Lai Technology Co.,LTD

Product: Boc-Lys(Cbz)-Ol 82689-20-1
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-21

82689-20-1, N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinolRelated Search:

N-Boc-N'-Cbz-L-lysine Boc-His(Trt)-OH Boc-D-Ser(Bzl)-OH N-BOC-O-Benzyl-L-serine N-Boc-N'-(2-chlorobenzyloxycarbonyl)-L-lysine BOC-LYS(Z)-OH DCHA BOC-LYS(Z)(ISOPROPYL)-OH BOC-LYS(Z)-OSU BOC-LYS(2-CHLORO-Z)-OH T-BUTYLAMINE NALPHA-(T-BUTOXYCARBONYL)-N-EPS-(CARBOB& BOC-L-LYS(2-CL-Z)-O-CH2-PHI-CH2-COOH BOC-LYS(4-NITRO-Z)-OH BOC-LYS(2-CHLORO-Z)-OSU BOC-L-MELYS(Z)-OH BOC-LYS(2-BROMO-Z)-OH N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol N-α-Boc-N-ε-Z-L-lysine N-carboxyanhydride BOC-LYS(2-CL-Z)-OL

(S)-Benzyl tert-butyl (6-hydroxyhexane-1,5-diyl)dicarbaMate

N-alpha-Boc-N-epsilon-Cbz-L-lysinol

Boc-L-Lys(Z)-ol

N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysinol

Boc-Lysinol(Z)-OH

Benzyl [(5S)-5-[[(tert-butyloxy)carbonyl]amino]-6-hydroxyhexyl]carbamate

Boc-L-Lysinol(Z)

Boc-L-Lys(Cbz)-OL

Na-Boc-Ne-Z-L-lysinol≥ 98% (HPLC)

Boc-Lys(Cbz)-Ol

Benzyl [(5S)-5-[[(tert-butyloxy)carbonyl]amino]-6-hydroxyhex

Boc-K(Z)-OL

Carbamic acid, N-[(5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-6-hydroxyhexyl]-, phenylmethyl ester

Benzyl tert-butyl (6-hydroxyhexane-1,5-diyl)(S)-dicarbamate

N-BOC-N'-CBZ-lysine

82689-20-1

Amino Acids