Boc-D-Ser(Bzl)-OH

Product Name: Boc-D-Ser(Bzl)-OH
CAS No.: 47173-80-8
Chemical Name: Boc-D-Ser(Bzl)-OH
Synonyms: O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE;BOC-SER(BZL)-OH;BOC-SER(BZL);BOC-D-SER(BZL);BOC-O-BENZYL-L-SERINE;(R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid;(2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid;BOC-L-SER(BZL);(2R)-3-(benzylox;BOC-D-SER(BZL)-OH
CBNumber: CB5438415
Molecular Formula: C15H21NO5
Formula Weight: 295.33
MOL File: 47173-80-8.mol

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Boc-D-Ser(Bzl)-OH Property

Melting point:: 58-60 °C(lit.)
alpha: -19 º (c=2 80% alcohol)
Boiling point:: 437.02°C (rough estimate)
Density: 1.1454 (rough estimate)
refractive index: -20 ° (C=2, 80% EtOH)
storage temp.: Sealed in dry,Room Temperature
solubility: almost transparency in Methanol
pka: 3.53±0.10(Predicted)
form: Powder
color: White
BRN: 2665080
InChI: InChI=1S/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)10-20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1
InChIKey: DMBKPDOAQVGTST-GFCCVEGCSA-N
SMILES: C(O)(=O)[C@@H](COCC1=CC=CC=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference: 47173-80-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 24/25-36-26
WGK Germany: 3
HS Code: 2924 29 70
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.53111
Product name: Boc-D-Ser(Bzl)-OH
Purity: Novabiochem?
Packaging: 25g
Price: $196
Updated: 2024/03/01

Sigma-Aldrich

Product number: 15078
Product name: Boc-D-Ser(Bzl)-OH
Purity: ≥98.0% (HPLC)
Packaging: 5g
Price: $413
Updated: 2024/03/01

TCI Chemical

Product number: B1863
Product name: O-Benzyl-N-(tert-butoxycarbonyl)-D-serine
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $66
Updated: 2024/03/01

TCI Chemical

Product number: B1863
Product name: O-Benzyl-N-(tert-butoxycarbonyl)-D-serine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $212
Updated: 2024/03/01

Alfa Aesar

Product number: B22666
Product name: N-Boc-O-benzyl-D-serine, 99%
Packaging: 5g
Price: $180
Updated: 2021/12/16

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Boc-D-Ser(Bzl)-OH Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

N-BOC-O-Benzyl-D-serine, is an amino acid derivative used in chemical synthesis and peptide chemistry.is used in preparation of substituted naphthyl thiadiazolidinones as protein tyrosine phosphatase degraders for treating cancer and metabolic diseases.

Biological Activity

Boc-O-benzyl-D-serine is an inhibitor of the uptake of galactose and its derivatives. It has potent inhibitory activity against the uptake of galactose, glucose, and lactose. This drug is also effective in inhibiting the uptake of tetrazole, a substance that inhibits glycolysis. Boc-O-benzyl-D-serine is able to inhibit atherosclerotic lesions caused by piperidine, which has been shown to be synthesized from benzyl alcohol and piperidine. The oral administration of this compound can enhance fibroblast cells that are resistant to insulin.

Synthesis

N-Boc D-Se (500 mg, 2.43 mmol) dissolved in anhydrous DMF (4 mL) was slowly added to a dispersion of 60% NaH (204 mg, 5.1 mmol) in anhydrous DMF at 0 ° C. Stir the mixture at room temperature for 1 hour and cool to 0 ° C. Subsequently, benzyl bromide (0.29 mL, 2.43 mmol) was added and the mixture was heated to room temperature. After 4 hours of reaction, add saturated NH4Cl (1 mL) to quench the reaction. Finally, the product Boc-D-Ser(Bzl)-OH was obtained through purification.

Boc-D-Ser(Bzl)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-D-Ser(Bzl)-OH Suppliers

Americas 1 Belgium 1 China 187 Europe 2 France 1 Germany 5 Hungary 1 India 9 Ireland 1 Japan 10 Switzerland 5 United Kingdom 7 United States 43 Global 273

Sichuan HongRi Pharma-Tech Co., Ltd

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Energy Chemical

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GL Biochem (Shanghai) Ltd

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View Lastest Price from Boc-D-Ser(Bzl)-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-D-Ser(Bzl)-OH 47173-80-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-27

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Boc-D-Ser(Bzl)-OH 47173-80-8
Price: US $32.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-05-15

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Boc-D-Ser(Bzl)-OH 47173-80-8
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-09-23

47173-80-8, Boc-D-Ser(Bzl)-OHRelated Search:

Benzyl chloride D-Serine Benzyl benzoate L-Homoserine tert-Butanol Boc-Ser(tBu)-OH N-Carbobenzyloxyglycine Benzyl bromide DL-Serine Benzyltriethylammonium chloride Benzyl alcohol L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE Boc-Aib-OH D-Cycloserine Benzyltrimethylammonium chloride Boc-O-benzyl-L-serine, N-(tert-Butoxycarbonyl)-O-benzyl-L-serine,N-BOC-O-Benzyl-L-serine,N-T-BOC-O-BENZYL-L-SERINE CRYSTALLINE BOC-GLY-LEU-OH Boc-His(Trt)-OH

(2R)-2-(tert-butoxycarbonylamino)-3-(phenylmethoxy)propanoic acid

(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(phenylmethoxy)propanoic acid

(2R)-2-[(tert-butoxy-oxomethyl)amino]-3-(phenylmethoxy)propanoic acid

(2R)-3-(benzyloxy)-2-(tert-butoxycarbonylamino)propionic acid

L-Serine, N-((1,1-dimethylethoxy)carbonyl)-O-(phenylmethyl)-

Boc-D-Ser(Bzl)-OH, >=98%

BOC-D-SERINE(BZL)-OH

BOC-D-SER(BZL)-OH

BOC-SER(BZL)-OH

BOC-SER(BZL)

BOC-SERINE(BZL)-OH

BOC-(S)-2-AMINO-3-BENZYLOXYPROPIONIC ACID

BOC-O-BENZYL-D-SERINE

BOC-O-BENZYL-L-SERINE

BOC-(R)-2-AMINO-3-BENZYLOXYPROPIONIC ACID

BOC-L-SER(BZL)-OH

BOC-L-SERINE (BZL)

BOC-L-SER(BZL)

O-Benzyl-N-(tert-butoxycarbonyl)-D-serine

Boc-O-benzyl-D-serine≥ 99.5% (HPLC)

NALPHA-tert-Butoxycarbonyl-O-benzyl-D-serine

N-BOC-O-Benzyl-D-serine,98%

N-t-BOC-O-Benzyl-D-serine

N-Boc-O-Benzyl-D-ser

Boc-D-Ser(Bzl)-OH Boc-O-benzyl-D-Serine

N-Boc-O-benzyl-D-serine Boc-D-Ser(Bzl)-OH

(R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid

T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE

T-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE

TBOC-L-SERINE (BZL)

N-ALPHA-T-BOC-O-BENZYL-L-SERINE

N-ALPHA-T-BOC-O-BENZYL-D-SERINE

N-ALPHA-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE

N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE

N-ALPHA-TERT-BOC-O-BENZYL-L-SERINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE

N-BOC-O-BENZYL-D-SERINE

Boc-DL-Ser(Bzl)-OH

O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE

N-TERT-BUTOXYCARBONYL-O-BENZYL-D-SERINE

N-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE

(Tert-Butoxy)Carbonyl D-Ser(Bzl)-OH

(2R)-3-(benzylox

BOC-D-SER(BZL)

(2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid

O-Benzyl-N-Boc-D-serine

O-Benzyl-N-(tert-butoxycarbonyl)-D-serine &gt

D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-

N-[(1,1-Dimethylethoxy)carbonyl]-O-(phenylmethyl)-D-serine

(s)-(+)-3-Benzyloxy-2-(Boc-amino)-1-propanol

BOC-D-Ser(OBZL)-OH

47173-80-8

47473-80-8

47173-80-6

C15H20NO5

Specialty Synthesis

Peptide Synthesis