Boc-D-Ser(Bzl)-OH
- Product Name
- Boc-D-Ser(Bzl)-OH
- CAS No.
- 47173-80-8
- Chemical Name
- Boc-D-Ser(Bzl)-OH
- Synonyms
- O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE;BOC-SER(BZL)-OH;BOC-SER(BZL);BOC-D-SER(BZL);BOC-O-BENZYL-L-SERINE;(R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid;(2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid;BOC-L-SER(BZL);(2R)-3-(benzylox;BOC-D-SER(BZL)-OH
- CBNumber
- CB5438415
- Molecular Formula
- C15H21NO5
- Formula Weight
- 295.33
- MOL File
- 47173-80-8.mol
Boc-D-Ser(Bzl)-OH Property
- Melting point:
- 58-60 °C(lit.)
- alpha
- -19 º (c=2 80% alcohol)
- Boiling point:
- 437.02°C (rough estimate)
- Density
- 1.1454 (rough estimate)
- refractive index
- -20 ° (C=2, 80% EtOH)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- almost transparency in Methanol
- pka
- 3.53±0.10(Predicted)
- form
- Powder
- color
- White
- BRN
- 2665080
- InChI
- InChI=1S/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)10-20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1
- InChIKey
- DMBKPDOAQVGTST-GFCCVEGCSA-N
- SMILES
- C(O)(=O)[C@@H](COCC1=CC=CC=C1)NC(OC(C)(C)C)=O
- CAS DataBase Reference
- 47173-80-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- HS Code
- 2924 29 70
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.53111
- Product name
- Boc-D-Ser(Bzl)-OH
- Purity
- Novabiochem?
- Packaging
- 25g
- Price
- $196
- Updated
- 2024/03/01
- Product number
- 15078
- Product name
- Boc-D-Ser(Bzl)-OH
- Purity
- ≥98.0% (HPLC)
- Packaging
- 5g
- Price
- $413
- Updated
- 2024/03/01
- Product number
- B1863
- Product name
- O-Benzyl-N-(tert-butoxycarbonyl)-D-serine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $66
- Updated
- 2024/03/01
- Product number
- B1863
- Product name
- O-Benzyl-N-(tert-butoxycarbonyl)-D-serine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $212
- Updated
- 2024/03/01
- Product number
- B22666
- Product name
- N-Boc-O-benzyl-D-serine, 99%
- Packaging
- 5g
- Price
- $180
- Updated
- 2021/12/16
Boc-D-Ser(Bzl)-OH Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Uses
N-BOC-O-Benzyl-D-serine, is an amino acid derivative used in chemical synthesis and peptide chemistry.is used in preparation of substituted naphthyl thiadiazolidinones as protein tyrosine phosphatase degraders for treating cancer and metabolic diseases.
Biological Activity
Boc-O-benzyl-D-serine is an inhibitor of the uptake of galactose and its derivatives. It has potent inhibitory activity against the uptake of galactose, glucose, and lactose. This drug is also effective in inhibiting the uptake of tetrazole, a substance that inhibits glycolysis. Boc-O-benzyl-D-serine is able to inhibit atherosclerotic lesions caused by piperidine, which has been shown to be synthesized from benzyl alcohol and piperidine. The oral administration of this compound can enhance fibroblast cells that are resistant to insulin.
Synthesis
N-Boc D-Se (500 mg, 2.43 mmol) dissolved in anhydrous DMF (4 mL) was slowly added to a dispersion of 60% NaH (204 mg, 5.1 mmol) in anhydrous DMF at 0 ° C. Stir the mixture at room temperature for 1 hour and cool to 0 ° C. Subsequently, benzyl bromide (0.29 mL, 2.43 mmol) was added and the mixture was heated to room temperature. After 4 hours of reaction, add saturated NH4Cl (1 mL) to quench the reaction. Finally, the product Boc-D-Ser(Bzl)-OH was obtained through purification.
Boc-D-Ser(Bzl)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Boc-D-Ser(Bzl)-OH manufacturers
- Product
- Boc-D-Ser(Bzl)-OH 47173-80-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2023-09-27
- Product
- Boc-D-Ser(Bzl)-OH 47173-80-8
- Price
- US $32.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-15
- Product
- Boc-D-Ser(Bzl)-OH 47173-80-8
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500kgs
- Release date
- 2021-09-23