S-Methyl-L-cysteine Property

Melting point:

~240 °C (dec.)

alpha 

-29.5 º (c=1,water)

Boiling point:

300.3±37.0 °C(Predicted)

Density 

1.149 (estimate)

refractive index 

-30 ° (C=2, H2O)

storage temp. 

Keep in dark place,Sealed in dry,Store in freezer, under -20°C

solubility 

Aqueous Acid (Slightly, Sonicated), Aqueous Base (Sparingly, Sonicated)

form 

Solid

pka

pK1:8.97 (25°C)

color 

White to Off-White

BRN 

1721675

LogP

0.380 (est)

CAS DataBase Reference

1187-84-4(CAS DataBase Reference)

NIST Chemistry Reference

s-Methyl-L-cysteine(1187-84-4)

Safety

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

22-24/25-36/37/39-26

WGK Germany 

3

HS Code 

29309090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

S-Methyl-L-cysteine Chemical Properties,Usage,Production

Chemical Properties

white to light beige fine crystalline powder

Uses

S-Methyl-L-cysteine is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA). It has been studied as a theurapeutic for neurodegenerative diseases including Parkinson′s.

Definition

ChEBI: A cysteine derivative that is L-cysteine in which the hydrogen attached to the sulfur is replaced by a methyl group.

Purification Methods

Likely impurities are cysteine and S-methyl-dl-cysteine. Crystallise it from H2O by adding 4volumes of EtOH. It also crystallises from MeOH with m 234-236o(dec), but after sublimation i t has m 267-270o and [] 27D -31.6o (c 1, H2O). [Rinderknecht et al. Helv Chim Acta 41 1, 10 1958, Theodoropoulos Acta Chem Scand 13 383 1959, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1904 1961, Beilstein 4 IV 3145.]