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2-Octyl-1-dodecanol

Product Name
2-Octyl-1-dodecanol
CAS No.
5333-42-6
Chemical Name
2-Octyl-1-dodecanol
Synonyms
1-Dodecanol, 2-octyl-;OCTYL DODECANOL;2-OctyL;exxal20;BASF OD;eutanolg;Guerbet20;rilanitg20;9-Icosanol;JARCOL 1-20
CBNumber
CB4164735
Molecular Formula
C20H42O
Formula Weight
298.55
MOL File
5333-42-6.mol
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2-Octyl-1-dodecanol Property

Melting point:
−1-1 °C(lit.)
Boiling point:
234-238 °C/33 mmHg(lit.)
Density 
0.838 g/mL at 25 °C(lit.)
vapor pressure 
0.1Pa at 148.85℃
refractive index 
n20/D 1.453(lit.)
Flash point:
113 °C
storage temp. 
2-8°C
solubility 
Practically insoluble in water, miscible with ethanol (96 per cent).
pka
15.03±0.10(Predicted)
color 
Colourless
Water Solubility 
10μg/L at 23℃
InChIKey
LEACJMVNYZDSKR-UHFFFAOYSA-N
LogP
8.63 at 20℃
EPA Substance Registry System
2-Octyldodecanol (5333-42-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
nwg
RTECS 
JR4240000
HS Code 
2905199095
Toxicity
skn-rat 100 mg/24H MOD CTOIDG 94(8),41,79
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
464481
Product name
2-Octyl-1-dodecanol
Purity
97%
Packaging
25ml
Price
$60.4
Updated
2024/03/01
TCI Chemical
Product number
O0429
Product name
2-n-Octyl-1-dodecanol
Purity
>90.0%(GC)
Packaging
25mL
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
O0429
Product name
2-n-Octyl-1-dodecanol
Purity
>90.0%(GC)
Packaging
500mL
Price
$291
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR1155
Product name
Octyldodecanol
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
1g
Price
$97.5
Updated
2024/03/01
Sigma-Aldrich
Product number
O0101000
Product name
Octyldodecanol
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
o0101000
Price
$153
Updated
2024/03/01
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2-Octyl-1-dodecanol Chemical Properties,Usage,Production

Chemical Properties

Octyldodecanol occurs as a clear, colorless, or yellowish, oily liquid.

Chemical Properties

2-Octyl-1-dodecanol is clear, colourless or yellowish, oily liquid.

Uses

2-Octyldodecane-1-ol have been used as a emulsion stabilizer for polymer matrix patches.

Uses

2-Octyl-1-dodecanol may be used to investigate its interaction with the hexameric capsules of resorcin[4]arene. It has been used as diluent in a extractant screening study for the recovery of putrescine (butylene-1,4-diamine, BDA) and cadaverine (pentylene-1,5-diamine, PDA) from aqueous solutions (fermentation broths) by liquid-liquid extraction.

Uses

2-Octyl-1-dodecanol have been used as a emulsion stabilizer for polymer matrix patches.

Production Methods

2-Octyl-1-dodecanol is produced by the condensation of two molecules of decyl alcohol. It also occurs naturally in small quantities in plants.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Pharmaceutical Applications

Octyldodecanol is widely used in cosmetics and pharmaceutical applications as an emulsifying and opacifying agent. It is primarily used in topical applications because of its lubricating and emollient properties.
Octyldodecanol has been used in the preparation of oil/water microemulsions investigated as the vehicle for the dermal administration of drugs having no or low skin penetration.Octyldodecanol has also been evaluated as a solvent for naproxen when applied topically.Studies of estimated permeability coefficient suggest that octyldodecanol could be a potential dermal permeation enhancer.

Safety Profile

An eye and severe skin irritant.When heated to decomposition it emits acrid smoke andirritating vapors.

Safety

Octyldodecanol is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as nontoxic and nonirritant at the levels employed as an excipient.
In acute oral toxicity studies in rats fed 5 g/kg of undiluted octyldodecanol, no deaths were observed.In an acute dermal toxicity study, intact and abraded skin sites of guinea pigs were treated with 3 g/kg of undiluted octyldodecanol under occlusive patches; no deaths occurred and no gross skin lesions were observed.Octyldodecanol caused either no ocular irritation or minimal, transient irritation in the eyes of rabbits.However, some sources describe undiluted octyldodecanol as an eye and severe skin irritant.

storage

The bulk material should be stored in a well-closed container in a cool, dry place, protected from light. In the original unopened container, octyldodecanol can be stored for 2 years protected from moisture at below 30°C.

Incompatibilities

2-Octyl-1-dodecanol is generally compatible with most materials encountered in cosmetic and pharmaceutical formulations.

Regulatory Status

Included in the FDA Inactive Ingredients Database (topical, transdermal, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

2-Octyl-1-dodecanol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Octyl-1-dodecanol Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from 2-Octyl-1-dodecanol manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2-Octyl-1-dodecanol 5333-42-6
Price
US $50.00-30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Month
Release date
2024-04-28
Shaanxi Haibo Biotechnology Co., Ltd
Product
2-Octyl-1-dodecanol 5333-42-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-31
Henan Fengda Chemical Co., Ltd
Product
2-Octyl-1-dodecanol 5333-42-6
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28

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