8-Bromo-1-naphthoic acid
- Product Name
- 8-Bromo-1-naphthoic acid
- CAS No.
- 1729-99-3
- Chemical Name
- 8-Bromo-1-naphthoic acid
- Synonyms
- Azvudine Impurity 12;8-BROMO-1-NAPHTHOIC ACID;8-Bromo-1-naphthoicacid98%;8-BROMO-1-NAPHTHOIC ACID: TECH.;8-Bromonaphthalene-1-carboxylic acid;8-Bromo-naphthalen-1-carboxylic acid;8-Bromo-1-naphthalenecarboxylic acid;1-Naphthalenecarboxylicacid, 8-bromo-;8-Bromonaphthalene-1-carboxylic acid, 8-Bromo-1-carboxynaphthalene
- CBNumber
- CB4166027
- Molecular Formula
- C11H7BrO2
- Formula Weight
- 251.08
- MOL File
- 1729-99-3.mol
8-Bromo-1-naphthoic acid Property
- Melting point:
- 162-164
- Boiling point:
- 421.2±18.0 °C(Predicted)
- Density
- 1.648±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.02±0.10(Predicted)
- Appearance
- Off-white to yellow Solid
- InChI
- InChI=1S/C11H7BrO2/c12-9-6-2-4-7-3-1-5-8(10(7)9)11(13)14/h1-6H,(H,13,14)
- InChIKey
- DMEZDDHJCUHENA-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)=C2C(C=CC=C2Br)=CC=C1
- CAS DataBase Reference
- 1729-99-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39-24/25
- Hazard Note
- Irritant
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S696854
- Product name
- 8-BROMO-1-NAPHTHOIC ACID
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $113
- Updated
- 2025/07/31
- Product number
- S696854
- Product name
- 8-BROMO-1-NAPHTHOIC ACID
- Purity
- AldrichCPR
- Packaging
- 250MG
- Price
- $106
- Updated
- 2023/06/20
- Product number
- B700430
- Product name
- 8-Bromo-1-naphthoicAcid
- Packaging
- 500mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 2621-9-Y6
- Product name
- 8-Bromo-1-naphthoic acid
- Purity
- 98.0%
- Packaging
- 250mg
- Price
- $87
- Updated
- 2021/12/16
- Product number
- 2621-9-Y6
- Product name
- 8-Bromo-1-naphthoic acid
- Purity
- 98.0%
- Packaging
- 1g
- Price
- $164
- Updated
- 2021/12/16
8-Bromo-1-naphthoic acid Chemical Properties,Usage,Production
Synthesis
6314-27-8
1729-99-3
Under stirring conditions, 1.0 g (2.70 mmol) of dehydrated-8-hydroxymercuric-1-naphthalenecarboxylic acid 26 was added to a mixture of 1.0 mL (67 mmol) acetic acid and 0.40 mL (22.2 mmol) H2O, and the suspension was stirred for 10 min at 0 °C. Subsequently, 0.89 g (8.66 mmol) of NaBr dissolved in 3.2 mL of water and 0.43 g (2.70 mmol) of bromine were added sequentially and the reaction system was slowly heated to 100 °C. After completion of the reaction, it was cooled to room temperature and the mixture was poured into ice and filtered to give 0.57 g (84% yield) of 8-bromo-1-naphthalenecarboxylic acid as a cream-colored solid with a melting point of 173-174 °C (literature value: 174-175 °C). The product was characterized by 1H NMR (500 MHz, DMSO-d6) and 13C NMR (125.77 MHz, DMSO-d6) with the following data: 1H NMR δ 7.49 (t, J = 7.8 Hz, 1H), 7.61 (t, J = 7.3 Hz, 1H), 7.68 (d, J = 7.0 Hz, 1H), 7.96 (d, J = 7.3 Hz, 1H), 8.07 (d, J=8.0 Hz, 1H), 8.11 (d, J=8.0 Hz, 1H), 13.32 (s, 1H); 13C NMR δ119.3,126.3,127.6,128.0,128.3,129.4,131.2,133.6,133.9,135.7, 171.3.
References
[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 6, p. 2067 - 2081
[2] Journal of Organic Chemistry, 1983, vol. 48, # 17, p. 2926 - 2928
8-Bromo-1-naphthoic acid Preparation Products And Raw materials
Raw materials
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View Lastest Price from 8-Bromo-1-naphthoic acid manufacturers
- Product
- 8-Bromo-1-naphthoic acid 1729-99-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 8-Bromo-1-naphthoic acid 1729-99-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09