1-HYDROXYPIPERIDINE
- Product Name
- 1-HYDROXYPIPERIDINE
- CAS No.
- 4801-58-5
- Chemical Name
- 1-HYDROXYPIPERIDINE
- Synonyms
- 1-piperidinol;piperidin-1-ol;Hydroxypiperidine;1-HYDROXYPIPERDINE;1-hydroxy-piperidin;N-HYDROXYPIPERIDINE;1-HYDROXYPIPERIDINE;Piperidine, 1-hydroxy-;Bupivacaine Impurity 27;1-HYDROXYPIPERIDINE 96+%
- CBNumber
- CB4185440
- Molecular Formula
- C5H11NO
- Formula Weight
- 101.15
- MOL File
- 4801-58-5.mol
1-HYDROXYPIPERIDINE Property
- Melting point:
- 37-39 °C
- Boiling point:
- 146-148℃ (1 Torr)
- Density
- 0.9903 (rough estimate)
- refractive index
- 1.4550 (estimate)
- Flash point:
- 78 °C
- storage temp.
- 2-8°C
- pka
- 14.19±0.20(Predicted)
- form
- low melting solid
- color
- White
- BRN
- 102726
- InChIKey
- LKPFBGKZCCBZDK-UHFFFAOYSA-N
- EPA Substance Registry System
- Piperidine, 1-hydroxy- (4801-58-5)
Safety
- WGK Germany
- 3
- RTECS
- TN6829550
- F
- 3-10
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 56207
- Product name
- 1-Hydroxypiperidine
- Purity
- ≥96.0% (GC)
- Packaging
- 1g
- Price
- $146
- Updated
- 2025/07/31
- Product number
- OR961933
- Product name
- 1-Hydroxypiperidine
- Purity
- 95%
- Packaging
- 1g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- OR961933
- Product name
- 1-Hydroxypiperidine
- Purity
- 95%
- Packaging
- 5g
- Price
- $480
- Updated
- 2021/12/16
- Product number
- CHM0006758
- Product name
- 1-HYDROXYPIPERIDINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $674.05
- Updated
- 2021/12/16
- Product number
- CD11117996
- Product name
- Piperidin-1-ol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
1-HYDROXYPIPERIDINE Chemical Properties,Usage,Production
Chemical Properties
Soluble in water, organic solvents, aqueous acids, and bases.
Uses
Base for Fmoc-based solid phase peptide synthesis
Light stabilizing agent
Uses
Base for Fmoc-based solid phase peptide synthesis1Light stabilizing agent2
Synthesis Reference(s)
The Journal of Organic Chemistry, 53, p. 5856, 1988 DOI: 10.1021/jo00260a012
Synthesis
110-89-4
4801-58-5
General procedure for the synthesis of N-hydroxypiperidine from hexahydropyridine: hexahydropyridine (5 mmol) and ChPS (5.5 mmol) were added to a round-bottomed flask under nitrogen protection, and the reaction was stirred for 1 hr at 60 °C. After completion of the reaction, the mixture was dissolved in water (5 mL) and the product was extracted with dichloromethane or ethyl acetate (5 mL each time, 3 times). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the target product N-hydroxypiperidine.
References
[1] Synlett, 2017, vol. 28, # 17, p. 2315 - 2319
[2] Tetrahedron Letters, 2001, vol. 42, # 20, p. 3419 - 3422
[3] Justus Liebigs Annalen der Chemie, 1948, vol. 559, p. 1,22, 23
[4] Chemische Berichte, 1951, vol. 84, p. 690,698
[5] Chemische Berichte, 1892, vol. 25, p. 2782
1-HYDROXYPIPERIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
1-HYDROXYPIPERIDINE Suppliers
- Tel
- --
- Fax
- --
- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from 1-HYDROXYPIPERIDINE manufacturers
- Product
- 1-HYDROXYPIPERIDINE 4801-58-5
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08