ChemicalBook > CAS DataBase List > 4-Chromanone

4-Chromanone

Product Name
4-Chromanone
CAS No.
491-37-2
Chemical Name
4-Chromanone
Synonyms
CHROMAN-4-ONE;CHROMANONE;Isochromanone;2,3-Dihydro-4H-1-benzopyran-4-one;4-chormanone;4-CHROMANONE;4-Chlomanone;CHROMANONE, 4-;4-Chromanone,99%;4-Chromanone >
CBNumber
CB4191157
Molecular Formula
C9H8O2
Formula Weight
148.16
MOL File
491-37-2.mol
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4-Chromanone Property

Melting point:
35-38 °C(lit.)
Boiling point:
127-128 °C13 mm Hg(lit.)
Density 
1.1291
refractive index 
n20/D 1.575(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder, Crystals or Low Melting Mass
color 
White to yellow
Water Solubility 
Slightly soluble in water.
BRN 
124652
InChIKey
MSTDXOZUKAQDRL-UHFFFAOYSA-N
LogP
1.990 (est)
CAS DataBase Reference
491-37-2(CAS DataBase Reference)
NIST Chemistry Reference
4H-1-Benzopyran-4-one, 2,3-dihydro-(491-37-2)
EPA Substance Registry System
4H-1-Benzopyran-4-one, 2,3-dihydro- (491-37-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
33-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
2
RTECS 
DJ2981225
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
122351
Product name
4-Chromanone
Purity
97%
Packaging
10g
Price
$143
Updated
2024/03/01
TCI Chemical
Product number
C1175
Product name
4-Chromanone
Purity
>98.0%(GC)
Packaging
5g
Price
$59
Updated
2024/03/01
TCI Chemical
Product number
C1175
Product name
4-Chromanone
Purity
>98.0%(GC)
Packaging
25g
Price
$179
Updated
2024/03/01
Alfa Aesar
Product number
A11242
Product name
4-Chromanone, 98+%
Packaging
5g
Price
$51.65
Updated
2024/03/01
Alfa Aesar
Product number
A11242
Product name
4-Chromanone, 98+%
Packaging
25g
Price
$173.65
Updated
2024/03/01
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4-Chromanone Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

4-Chromanone has been used to study the substrate specificity and catalytic ability of 4-hydroxyacetophenone monooxygenase isolated from Pseudomonas fluorescens ACB

Definition

ChEBI: 4-Chromanone is a member of chromones.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 5160, 1983 DOI: 10.1021/jo00174a003

Purification Methods

It has been recrystallised from pet ether, or purified by dissolving in *C6H6 washing with H2O, drying (MgSO4), evaporating and distilling in a vacuum, then recrystallising the residue. The liquid has a pleasant lemon-like odour. The semicarbazone has m 227o. [Loudon & Razdan J Chem Soc 4299 1954.] The oxime is prepared from 3g of chromanone, 3g NH2OH.HCl in EtOH (50mL), 6g K2CO3 and refluxed on a water bath for 6hours. The solution is poured into H2O, the solid is filtered off, dried and dissolved in hot *C6H6 which on addition of pet ether yields the oxime as glistening needles m 140o. Hydrolysis of this gives very pure chromanone. The benzal derivative is prepared from 3g of chromanone and 4g PhCHO in 50mL EtOH, heated to boiling, 10mL of conc HCl are added dropwise and set aside for several days. The derivative separates and is recrystallised from EtOH to give yellow needles, m 112o [Powell J Am Chem Soc 45 2711 1923]. Reaction with Pb(OAc)4 yields the 3-acetoxy derivative m 74o (from pet ether + trace of EtOAc) [Cavill et al. J Chem Soc 4573 1954, Beilstein 17/10V 14].

4-Chromanone Preparation Products And Raw materials

Raw materials

Phosphoric acid Phenol 3-Bromopropionic acid Sodium hydroxide Phosphorus pentoxide

Preparation Products

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4-Chromanone Suppliers

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View Lastest Price from 4-Chromanone manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4-Chromanone 491-37-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-04-27
Hebei Mojin Biotechnology Co., Ltd
Product
4-Chromanone 491-37-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-07-28
Dideu Industries Group Limited
Product
4-Chromanone 491-37-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-28

491-37-2, 4-ChromanoneRelated Search:

Potassium hydrogen phthalate Oxybenzone Tetrahydro-4H-pyran-4-one Benzophenone Dihydromyrcenol Centchroman DIETHYLPROPION 6-Bromo-4-chromanone 4-CHROMANONE 6-Fluoro-4-chromanone 6-Methoxy-3-chromanone 8-Fluoro-4-chromanone 7-Fluoro-4-chromanone 6-Methoxy-4-chromanone 6-Nitro-4-chromanone 6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE 8-Methoxy-3-chromanone 7-Fluoro-3-chromanone

  • Isochromanone
  • ,3-Dihydro-2-benzopyran-4-one
  • ,3-Dihydro-4-benzopyranone
  • 2,3-dihydro-4-benzopyranone
  • 2,3-dihydro-4h-1-benzopyran-4-on
  • 2,3-Dihydro-4H-1-benzopyran-4-one
  • 4-chormanone
  • JRH-01801, Chroman-4-one, 97%
  • CHROMANONE
  • CHROMANONE, 4-
  • CHROMAN-4-ONE
  • 2,3-DIHYDRO-4H-CHROMEN-4-ONE
  • 2,3-DIHYDRO-1-BENZOPYRAN-4-ONE
  • 2,4-DIHYDRO-1-BENZOPYRAN-4-ONE
  • 4-CHROMANONE
  • 4-Chlomanone
  • ChondrotinSulfateBp98
  • 4-Chromanone, 98+%
  • 4-Chromanone,99%
  • dihydrobenz-γ-pyrone
  • 2H-1-Benzopyran-4(3H)-one
  • 2,3-dihydrochroMen-4-one
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-
  • 2,3-Dihydro-1-benzopyran-4-one, 2,3-Dihydro-4H-chromen-4-one
  • 4-Chromanone &gt
  • 4-Chromanone ISO 9001：2015 REACH
  • 491-37-2
  • Heterocyclic Building Blocks
  • KETONE
  • Building Blocks
  • Benzopyrans
  • Fused Ring Systems