ChemicalBook > CAS DataBase List > 3-Hydroxyphenylboronic acid

3-Hydroxyphenylboronic acid

Product Name
3-Hydroxyphenylboronic acid
CAS No.
87199-18-6
Chemical Name
3-Hydroxyphenylboronic acid
Synonyms
AKOS BRN-0182;3-boronophenol;RARECHEM AH PB 0221;3-Hydroxyphenylboron;3-Hydroxyphenylboronic;3-hydroxyphenylboric acid;N-fluorodiphenylsulfonamide;3-HYDROXYPHENYLBORONIC ACID;M-HYDROXYPHENYLBORONIC ACID;3-HYDROXYBENZENEBORONIC ACID
CBNumber
CB4204923
Molecular Formula
C6H7BO3
Formula Weight
137.93
MOL File
87199-18-6.mol
More
Less

3-Hydroxyphenylboronic acid Property

Melting point:
210-213 °C (dec.) (lit.)
Boiling point:
370.0±44.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder, Crystals and/or Chunks
pka
pK1:8.55;pK2:10.84 (25°C)
color 
Pink to gray to tan
BRN 
3240771
InChI
InChI=1S/C6H7BO3/c8-6-3-1-2-5(4-6)7(9)10/h1-4,8-10H
InChIKey
WFWQWTPAPNEOFE-UHFFFAOYSA-N
SMILES
B(C1=CC=CC(O)=C1)(O)O
CAS DataBase Reference
87199-18-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-22
Safety Statements 
37/39-26-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29319090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
523968
Product name
3-Hydroxyphenylboronic acid
Purity
≥95.0%
Packaging
1g
Price
$54.7
Updated
2025/07/31
Sigma-Aldrich
Product number
523968
Product name
3-Hydroxyphenylboronic acid
Purity
≥95.0%
Packaging
10g
Price
$103
Updated
2025/07/31
TCI Chemical
Product number
H1185
Product name
3-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride)
Packaging
1g
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
H1185
Product name
3-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$60
Updated
2025/07/31
TRC
Product number
H952918
Product name
3-Hydroxyphenylboronic acid
Packaging
500mg
Price
$65
Updated
2021/12/16
More
Less

3-Hydroxyphenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

suzuki reaction

Uses

3-Hydroxyphenylboronic acid (3-HPBA) can be used as a reagent:

  • In Suzuki-Miyaura coupling reactions with aryl halides for the formation of C-C bond in the presence of Pd catalyst.
  • ?To synthesize boron/nitrogen-doped polymer nano/microspheres by hydrothermal polymerization with formaldehyde and ammonia.??????
  • To prepare carbon quantum dots based on 3-HPBA as selective fructose sensor.?????
  • In the development of modified electrodes for electrochemical biosensors.

Synthesis

121-43-7

591-20-8

87199-18-6

(vi) Preparation of 3-hydroxyphenylboronic acid: m-Bromophenol (8.65 g, 50 mmol) was dissolved in anhydrous tetrahydrofuran (150 mL) and sodium hydride (60%, 2.4 g, 60 mmol) was added at room temperature. After 1 hour of reaction, sec-butyl lithium (1.3 M, 50 mL, 65 mmol) was added slowly and dropwise to the reaction solution at -78 °C. Stirring was continued at this temperature for 30 min, followed by the addition of trimethyl borate (15 mL). The reaction system was gradually warmed to room temperature and maintained for 2 hours. Upon completion of the reaction, the reaction was quenched with deionized water (50 mL) and extracted with dichloromethane (2 x 100 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to afford 3-hydroxyphenylboronic acid as a white solid (4.0 g, 58% yield), and the product was used directly in the subsequent Suzuki coupling reaction without further purification.

References

[1] Patent: US2003/187022, 2003, A1

3-Hydroxyphenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-Hydroxyphenylboronic acid Suppliers

Americas 1 Belgium 2 China 267 Europe 4 France 1 Germany 9 India 10 Japan 2 Jordan 1 Russia 1 Slovakia 1 Switzerland 1 Ukraine 1 United Kingdom 13 United States 44 Global 358
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Acros Organics USA
Tel
--
Fax
--
Email
eveleth@fisherchem.com
Country
United States
ProdList
3846
Advantage
81
AOBChem USA
Tel
--
Fax
--
Email
sales@aobchem.com
Country
United States
ProdList
3487
Advantage
50
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
Pure Chemistry Scientific Inc
Tel
--
Fax
--
Email
sales@purechems.com
Country
United States
ProdList
2321
Advantage
50
Angene International Limited
Tel
--
Fax
--
Email
sales@angenechemical.com
Country
United States
ProdList
100
Advantage
50
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
Louston International
Tel
--
Fax
--
Email
sales@louston.com
Country
United States
ProdList
525
Advantage
58
HDH Pharma, Inc.
Tel
--
Fax
--
Email
catalog@hdhpharma.com
Country
United States
ProdList
6248
Advantage
62
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Boron Molecular Inc.
Tel
--
Fax
--
Email
sales@boronmolecular-usa.com
Country
United States
ProdList
996
Advantage
65
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
AstaTech, Inc
Tel
--
Fax
--
Email
sales@astatechinc.com
Country
United States
ProdList
6371
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
GL CHEMTEC INTERNATIONAL LIMITED
Tel
--
Fax
--
Email
products@glchemtec.ca
Country
United States
ProdList
216
Advantage
66
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Bio-Vin Research Laboratories
Tel
--
Fax
--
Email
sales@biovinresearch.com
Country
United States
ProdList
6210
Advantage
64
Aagile Labs Division of Tyger Scientific
Tel
--
Fax
--
Email
tygersci@yahoo.com
Country
United States
ProdList
6568
Advantage
68
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
Advantage
38
Syntech Labs
Tel
--
Fax
--
Email
info@syntechlabs.com
Country
United States
ProdList
730
Advantage
43
Digital Specialty Chemicals, Inc.
Tel
--
Fax
--
Email
sales@digitalchem.com
Country
United States
ProdList
710
Advantage
85
Cuschem, Inc.
Tel
--
Fax
--
Country
United States
ProdList
353
Advantage
42
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
Ryscor Science Inc.
Tel
--
Fax
--
Email
sales@ryscor.com
Country
United States
ProdList
394
Advantage
68
Optimachem
Tel
--
Fax
--
Email
dmills@optimachem.com
Country
United States
ProdList
255
Advantage
66
Asymchem Laboratories, Inc.
Tel
--
Fax
--
Email
info@asymchem.com
Country
United States
ProdList
1315
Advantage
69
Charkit Chemical Corporation
Tel
--
Fax
--
Email
sales@charkit.com
Country
United States
ProdList
2993
Advantage
65
Ennova MedChem Group Inc., formerly Arch Corporation
Tel
--
Fax
--
Email
sales@ennovamedchem.com
Country
United States
ProdList
1218
Advantage
42
More
Less

View Lastest Price from 3-Hydroxyphenylboronic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
3-Hydroxyphenylboronic acid 87199-18-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-25
Henan Fengda Chemical Co., Ltd
Product
3-Hydroxyphenylboronic acid 87199-18-6
Price
US $34.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Hebei Xinsheng New Material Technology Co., LTD.
Product
3-Hydroxyphenylboronic acid 87199-18-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
30000 Kg
Release date
2023-11-30

87199-18-6, 3-Hydroxyphenylboronic acidRelated Search:

3,5-Dihydroxybenzoic acid 2,3,4-Trihydroxybenzoic acid Folic acid 4-Hydroxybenzaldehyde Phenylboronic acid Glycine Ethyl 2-(Chlorosulfonyl)acetate 4-Methoxyphenol Methylparaben 4'-Hydroxyacetophenone Triclosan 4-Hydroxybenzoic acid Citric acid Ascoric Acid 2-FORMYL-4,5-METHYLENEDIOXYPHENYLBORONIC ACID 3,4-Dimethoxyphenylboronic acid QUINOLINE-3-BORONIC ACID PINACOLATE 3-Methoxyphenylboronic acid

  • 3-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride)
  • 3-Hydroxyphenylboronic acid ,98%
  • 3-Hydroxyphenylboronic acid,97%
  • N-fluorodiphenylsulfonamide
  • 3-Hydroxyphenylboronic acid, May contain varying amounts of anhydride, 97%
  • m-Hydroxybenzeneboronic acid
  • 3-Hydroxyphenylboronic acid >=95.0%
  • B-(3-hydroxy-phenyl)boronic acid
  • BORONICACID, B-(3-HYDROXYPHENYL)-
  • 3-Hydroxybenzeneboronic Acid 3-Boronophenol
  • 3-HYDROXYBENZENEBORONIC ACID
  • 3-HYDROXYPHENYLBORONIC ACID
  • AKOS BRN-0182
  • RARECHEM AH PB 0221
  • M-HYDROXYPHENYLBORONIC ACID
  • 3-Boronophenol~3-Hydroxyphenylboronic acid
  • 3-Hydroxybenzeneboronicacid,97%
  • 3-Hydroxyphenylboronic
  • 3-boronophenol
  • 3-hydroxyphenylboric acid
  • 3-HYDROXYPHENYLBORONIC ACID 97%
  • 3-Hydroxybenzeneboronic acid 98%
  • 3-Hydroxyphenylboron
  • 3-Hydroxyphenylboronic acid - [H3740]
  • 87199-18-6
  • 97199-18-6
  • HOC6H4BOH2
  • Organometallic Reagents
  • Boronic Acids
  • Boronic Acids and Derivatives
  • Aryl
  • Substituted Boronic Acids
  • blocks
  • BoronicAcids
  • Boronate Ester
  • Potassium Trifluoroborate
  • Boronic Acids & Esters
  • Phenyls & Phenyl-Het
  • Organic acids
  • Boronic Acid
  • B (Classes of Boron Compounds)
  • Boronic Acids
  • Boronic Acids & Esters
  • Phenyls & Phenyl-Het
  • Boronic Acids
  • Boronic Acids and Derivatives
  • Aryl
  • Organoborons