ChemicalBook > CAS DataBase List > ansamitocin P-3

ansamitocin P-3

Product Name
ansamitocin P-3
CAS No.
66584-72-3
Chemical Name
ansamitocin P-3
Synonyms
Maytansinol isobutyrate;Tam-330;Tam 330;Nsc292222;MTA/CBR32;ANSAMITOCIN P-3;Ansamitosin P 3;Anasamitocin P-3;US-DMF No.: 034434;Ansamitocin p-3 90%
CBNumber
CB42130228
Molecular Formula
C32H43ClN2O9
Formula Weight
635.14
MOL File
66584-72-3.mol
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ansamitocin P-3 Property

Melting point:
190-192℃
Boiling point:
833.1±65.0 °C(Predicted)
Density 
1.29
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO: 100 mg/mL (157.45 mM);Ethanol: 55 mg/mL (86.60 mM)
pka
9.82±0.70(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
Water: Insoluble
InChIKey
OPQNCARIZFLNLF-VLSFGAMINA-N
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Safety

Hazard Codes 
Xn
Risk Statements 
20/22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
OQ2293000
HS Code 
2941900000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A2836
Product name
Ansamitocin P-3 from Actinosynnema pretiosum
Purity
≥90% (HPLC)
Packaging
1mg
Price
$366.1
Updated
2025/07/31
Usbiological
Product number
260184
Product name
Ansamitocin P3
Packaging
25mg
Price
$432
Updated
2021/12/16
AK Scientific
Product number
3448AH
Product name
AnsamitocinP-3
Packaging
1mg
Price
$115
Updated
2021/12/16
AK Scientific
Product number
3448AH
Product name
AnsamitocinP-3
Packaging
10mg
Price
$181
Updated
2021/12/16
ChemScene
Product number
CS-1568
Product name
AnsamitocinP-3
Purity
>98.0%
Packaging
50mg
Price
$540
Updated
2021/12/16
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ansamitocin P-3 Chemical Properties,Usage,Production

Description

Ansamitocin P 3 is a macrocyclic antitumor antibiotic that works by depolymerizing microtubules in both interphase and mitosis, and perturbs chromosome segregation.

Uses

Ansamitocin P-3 is an antitumor agent that binds to cell division protein FtsZ in Actinosynnema pretiosum.

Definition

ChEBI: A polyketide antibiotic that is isolated from Actinosynnema pretiosum and also exhibits antitumour activity.

IC 50

Maytansinoids

ansamitocin P-3 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ansamitocin P-3 manufacturers

Henan Bao Enluo International TradeCo.，LTD
Product
ansamitocin P-3 66584-72-3
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500t/month
Release date
2023-06-27
Zhuozhou Wenxi import and Export Co., Ltd
Product
Ansamitocin P-3" 66584-72-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Dideu Industries Group Limited
Product
ansamitocin P-3 66584-72-3
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-18

66584-72-3, ansamitocin P-3Related Search:

Maytansinol alpha-Cyperone beta-Eudesmol beta-Sitosterol MOSLOFLAVONE Hydroxyecdysone 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Artemether alpha-Terpineol hydroxygenkwanin (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one ANSAMITOCIN P-3

  • 2'-De(acetylmethylamino)-2'-methylmaytansine
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  • ANTIBIOTIC C 15003P3;MAYTANSINOL ISOBUTYRATE
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  • Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)
  • 11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2-methylpropanoate
  • Ansamitocin p-3, 10 mM in DMSO
  • Ansamitocin p-3 90%
  • (14S,16S,32R,33S,2R,4S,10Z,12E,14R)-86-Chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl isobutyrate
  • 66584-72-3
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