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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE

Product Name
BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
CAS No.
122266-55-1
Chemical Name
BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
Synonyms
NHS-SS-BIOTIN;Sulfo-SS-Biotin;Biotin-SS-NHS ester;NHS-SS-biotin,Biotin-SS-NHS;SULFOBIOTIN-X-NHS, CLEAVABLE;BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE;SULFOSUCCINIMIDYL-2-(BIOTINAMIDO)ETHYL-1,3-DITHIOPROPIONATE;SULFOSUCCINIMIDYL 2-(BIOTINAMIDE)ETHYL-1,3-DITHIOPROPIONATE;SULFOSUCCINIMIDYL 3-[[2-(BIOTINAMIDO)ETHYL] DITHIO]PROPIONATE;Propanoic acid, 3-[[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB4216304
Molecular Formula
C19H28N4O6S3
Formula Weight
504.64
MOL File
Mol file
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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Property

storage temp. 
0-6°C
solubility 
≥28.79 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A8006
Product name
NHS-SS-Biotin
Packaging
100mg
Price
$100
Updated
2021/12/16
BroadPharm
Product number
BP-22636
Product name
NHS-SS-biotin
Purity
90%
Packaging
100mg
Price
$290
Updated
2021/12/16
BroadPharm
Product number
BP-22636
Product name
NHS-SS-biotin
Purity
90%
Packaging
1g
Price
$1470
Updated
2021/12/16
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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Chemical Properties,Usage,Production

Description

NHS-SS-biotin is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. This biotin compound is membrane-permeable and useful for intracellular labeling. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.

Uses

NHS SS Biotin is a amine reactive biotinylation reagent that labels antibodies and other proteins and molecules that contain primary amines. NHS SS Biotin reacts efficiently with pirmary amino groups in alkaline buffers to form stable amide bonds. The disulfide bond in the spacer arm of NHS SS Biotin is also cleavable using reducing agents such as TCEP and DTT.

Biological Activity

nhs-ss-biotin (succinimidyl-2-(biotinamido)-ethyl-1,3-dithiopropionate) is a long-chain cleavable amine-reactive biotinylation reagent that has a spacer arm of 24.3 a in length due to the existence of a cross-bridge within its chemical structure. the long spacer arm creates an increased length between a covalently modified molecule and the bicyclic biotin rings that greatly enhances the ability of the molecule to bind to avidin or streptavidin probes. the nhs ester group of nhs-ss-biotin reacts with the amine groups of proteins and other molecule forming an amide bond and releasing of sulfo-nhs. nhs-ss-biotin is a water-insoluble molecule that requires the dissolution of organic solvents prior to be added to aqueous reactions.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Preparation Products And Raw materials

Raw materials

Preparation Products

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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
CovaChem, LLC.
Tel
+1815.714.8421 (direct)
Fax
+1815.315.1272
Email
tonynooner@covachem.com
Country
United States
ProdList
89
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4824
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
24969
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Hangzhou Huarong Pharm Co., Ltd.
Tel
571-86758373 +8613588754946
Fax
0086-571-81131109
Email
sales@huarongpharm.com
Country
CHINA
ProdList
3148
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
029-86217788 13892832556
Email
2440688701@qq.com
Country
China
ProdList
1993
Advantage
58
Jinan ponder chemical co. LTD
Tel
0531-0000
Email
thinklifescience@163.com
Country
China
ProdList
19689
Advantage
58
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View Lastest Price from BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-SS-NHS ester 122266-55-1
Price
US $0.00/mg
Min. Order
50mg
Purity
>95.00%
Supply Ability
50mg
Release date
2024-03-21

122266-55-1, BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLERelated Search:


  • SULFOBIOTIN-X-NHS, CLEAVABLE
  • SULFOSUCCINIMIDYL 2-(BIOTINAMIDE)ETHYL-1,3-DITHIOPROPIONATE
  • SULFOSUCCINIMIDYL-2-(BIOTINAMIDO)ETHYL-1,3-DITHIOPROPIONATE
  • SULFOSUCCINIMIDYL 3-[[2-(BIOTINAMIDO)ETHYL] DITHIO]PROPIONATE
  • NHS-SS-BIOTIN
  • BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
  • Sulfo-SS-Biotin
  • NHS-SS-biotin,Biotin-SS-NHS
  • Biotin-SS-NHS ester
  • Propanoic acid, 3-[[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-, 2,5-dioxo-1-pyrrolidinyl ester
  • 122266-55-1
  • C19H28N4O6S3
  • Biotinylation Reagents