BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE

Product Name: BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
CAS No.: 122266-55-1
Chemical Name: BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE
Synonyms: NHS-SS-BIOTIN;Sulfo-SS-Biotin;Biotin-SS-NHS ester;NHS-SS-biotin,Biotin-SS-NHS;SULFOBIOTIN-X-NHS, CLEAVABLE;BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE;SULFOSUCCINIMIDYL-2-(BIOTINAMIDO)ETHYL-1,3-DITHIOPROPIONATE;SULFOSUCCINIMIDYL 2-(BIOTINAMIDE)ETHYL-1,3-DITHIOPROPIONATE;SULFOSUCCINIMIDYL 3-[[2-(BIOTINAMIDO)ETHYL] DITHIO]PROPIONATE;Propanoic acid, 3-[[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB4216304
Molecular Formula: C19H28N4O6S3
Formula Weight: 504.64
MOL File: Mol file

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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Property

storage temp.: 0-6°C
solubility: ≥28.79 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: A8006
Product name: NHS-SS-Biotin
Packaging: 100mg
Price: $100
Updated: 2021/12/16

BroadPharm

Product number: BP-22636
Product name: NHS-SS-biotin
Purity: 90%
Packaging: 100mg
Price: $290
Updated: 2021/12/16

BroadPharm

Product number: BP-22636
Product name: NHS-SS-biotin
Purity: 90%
Packaging: 1g
Price: $1470
Updated: 2021/12/16

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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Chemical Properties,Usage,Production

Description

NHS-SS-biotin is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. This biotin compound is membrane-permeable and useful for intracellular labeling. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.

Uses

NHS SS Biotin is a amine reactive biotinylation reagent that labels antibodies and other proteins and molecules that contain primary amines. NHS SS Biotin reacts efficiently with pirmary amino groups in alkaline buffers to form stable amide bonds. The disulfide bond in the spacer arm of NHS SS Biotin is also cleavable using reducing agents such as TCEP and DTT.

Biological Activity

nhs-ss-biotin (succinimidyl-2-(biotinamido)-ethyl-1,3-dithiopropionate) is a long-chain cleavable amine-reactive biotinylation reagent that has a spacer arm of 24.3 a in length due to the existence of a cross-bridge within its chemical structure. the long spacer arm creates an increased length between a covalently modified molecule and the bicyclic biotin rings that greatly enhances the ability of the molecule to bind to avidin or streptavidin probes. the nhs ester group of nhs-ss-biotin reacts with the amine groups of proteins and other molecule forming an amide bond and releasing of sulfo-nhs. nhs-ss-biotin is a water-insoluble molecule that requires the dissolution of organic solvents prior to be added to aqueous reactions.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Preparation Products And Raw materials

Raw materials

Preparation Products

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BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE Suppliers

Canada 1 China 69 Japan 1 United Kingdom 2 United States 9 Global 82

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
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CovaChem, LLC.

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Tianjin Kailiqi Biotechnology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

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Shanghai Haohong Pharmaceutical Co., Ltd.

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TargetMol Chemicals Inc.

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Zhejiang J&C Biological Technology Co.,Limited

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Hangzhou Huarong Pharm Co., Ltd.

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 029-86217788 13892832556
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ProdList: 1993
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View Lastest Price from BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-SS-NHS ester 122266-55-1
Price: US $0.00/mg
Min. Order: 50mg
Purity: >95.00%
Supply Ability: 50mg
Release date: 2024-03-21

122266-55-1, BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLERelated Search:

Azide-SS-biotin Sulfo-NHS-SS-Biotin N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE Sulfo-NHS-Biotin BIOTIN-NHS Biotin-PEG3-oxyamine BIOTINAMIDOCAPROYL HYDRAZIDE Biotin-PEG3-propionic hydrazide BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER BIOTIN HYDRAZIDE DBCO-S-S-PEG3-Biotin N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE

SULFOBIOTIN-X-NHS, CLEAVABLE

SULFOSUCCINIMIDYL 2-(BIOTINAMIDE)ETHYL-1,3-DITHIOPROPIONATE

SULFOSUCCINIMIDYL-2-(BIOTINAMIDO)ETHYL-1,3-DITHIOPROPIONATE

SULFOSUCCINIMIDYL 3-[[2-(BIOTINAMIDO)ETHYL] DITHIO]PROPIONATE

NHS-SS-BIOTIN

BIOTIN-X-NHS, WATER-SOLUBLE, CLEAVABLE

Sulfo-SS-Biotin

NHS-SS-biotin,Biotin-SS-NHS

Biotin-SS-NHS ester

Propanoic acid, 3-[[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-, 2,5-dioxo-1-pyrrolidinyl ester

122266-55-1

C19H28N4O6S3

Biotinylation Reagents