5-Methoxyindole
- Product Name
- 5-Methoxyindole
- CAS No.
- 1006-94-6
- Chemical Name
- 5-Methoxyindole
- Synonyms
- 5-METHOXY-1H-INDOLE;Methoxyindole 99% indol-5-yl methyl ether;5-methoxy-indol;Femedol;NSC 521752;AKOS JY2082918;5-METHOXYINDOLE;methoxy-5indole;5-MethoxyindoleF;Methoxy-5 indole
- CBNumber
- CB4223553
- Molecular Formula
- C9H9NO
- Formula Weight
- 147.17
- MOL File
- 1006-94-6.mol
5-Methoxyindole Property
- Melting point:
- 52-55 °C (lit.)
- Boiling point:
- 176-178 °C/17 mmHg (lit.)
- Density
- 1.1135 (rough estimate)
- refractive index
- 1.5310 (estimate)
- Flash point:
- 176-178°C/17mm
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform, Methanol
- form
- Crystalline Powder
- pka
- 16.70±0.30(Predicted)
- color
- White to light brownish
- Water Solubility
- insoluble
- Sensitive
- Light Sensitive
- BRN
- 116722
- InChIKey
- DWAQDRSOVMLGRQ-UHFFFAOYSA-N
- CAS DataBase Reference
- 1006-94-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 1H-Indole, 5-methoxy-(1006-94-6)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25-37/39
- WGK Germany
- 3
- RTECS
- NL9500000
- F
- 8
- Hazard Note
- Irritant
- HazardClass
- IRRITANT, KEEP COLD, LIGHT SENSITIVE
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M14900
- Product name
- 5-Methoxyindole
- Purity
- 99%
- Packaging
- 1g
- Price
- $26
- Updated
- 2024/03/01
- Product number
- M14900
- Product name
- 5-Methoxyindole
- Purity
- 99%
- Packaging
- 5g
- Price
- $35.4
- Updated
- 2024/03/01
- Product number
- M0731
- Product name
- 5-Methoxyindole
- Purity
- >99.0%(GC)
- Packaging
- 1g
- Price
- $42
- Updated
- 2024/03/01
- Product number
- M0731
- Product name
- 5-Methoxyindole
- Purity
- >99.0%(GC)
- Packaging
- 5g
- Price
- $72
- Updated
- 2024/03/01
- Product number
- B25290
- Product name
- 5-Methoxyindole, 99%
- Packaging
- 1g
- Price
- $36.65
- Updated
- 2024/03/01
5-Methoxyindole Chemical Properties,Usage,Production
Chemical Properties
white to light brownish crystalline powder
Uses
5-Methoxyindole (cas# 1006-94-6) is a compound useful in organic synthesis. It can be used to synthesis 1-(Phenylsulfonyl)-5-methoxy-1H-indole.
Preparation
The synthesis of 5-methoxyindole from 5-methoxy-2-oxindole: Conversion of 5-methoxy-2-oxindole to 5-methoxyindole was accomplishedby the chlorination of 5-methoxy-2-oxindole with triphenylphosphine-carbontetrachloride in acetonitrile followed by the catalytic reduction of a chlorine atom in 66% total yield.
Definition
ChEBI: 5-methoxyindole is a member of indoles.
Reactions
5-methoxyindole was treated with sodium hydroxide and phenylsulfonyl chloride in the presence of a catalytic amount of tetrabutylammonium bromide to afford 1-(phenylsulfonyl)indole and 5-methoxy-1-(phenylsufonyl)indole in excellent yields of 100%.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 26, p. 1405, 1989 DOI: 10.1002/jhet.5570260533
The Journal of Organic Chemistry, 58, p. 5558, 1993 DOI: 10.1021/jo00072a052
Tetrahedron Letters, 27, p. 837, 1986 DOI: 10.1016/S0040-4039(00)84114-3
Purification Methods
Crystallise 5-methoxyindole from cyclohexane pet ether or pet ether/Et2O. [Saito & Kikugawa J Heterocycl Chem 16 1325 1979, Beilstein 21 III/IV 765, 21/3 V 18.]
5-Methoxyindole Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from 5-Methoxyindole manufacturers
- Product
- 5-Methoxyindole 1006-94-6
- Price
- US $40.00-35.00/kg
- Min. Order
- 25kg
- Purity
- 99.9（%）
- Supply Ability
- 5000kg/month
- Release date
- 2024-03-29
- Product
- 5-Methoxyindole 1006-94-6
- Price
- US $129.00-645.00/g
- Min. Order
- 1g
- Purity
- 0.99
- Supply Ability
- 25kg
- Release date
- 2023-11-16
- Product
- 5-Methoxyindole 1006-94-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-06